Archive for the ‘research’ Category

Bartonella Infective Endocarditis With Dissemination: A Case Report & Literature Review

https://www.ncbi.nlm.nih.gov/m/pubmed/30155407/

Bartonella henselae infective endocarditis with dissemination: A case report and literature review in Southeast Asia.

Noopetch P, et al. IDCases. 2018.

Abstract

Bartonella is among the most common causes of culture-negative infective endocarditis, with B. henselae being one of the most frequently reported species. The clinical presentation of Bartonella endocarditis is similar to that of subacute bacterial endocarditis caused by other bacteria and the diagnosis can be challenging since the organism is difficult to isolate using standard microbiologic culture techniques. In clinical practice, Bartonella endocarditis is usually diagnosed based on serology. To date, only a handful of cases of infective endocarditis caused by Bartonella have been reported in Thailand. Here, we report the case of 51-year-old Thai male with B. henselae endocarditis with dissemination to the lungs, bones, subcutaneous tissue (below dermis, and is primarily loose connective tissue and lobules of fat), epididymis (coiled tube at the back of the testes), and lymph nodes with a successful outcome.

________________

**Comment**

Please notice the dissemination to lungs, bones, testes, lymph nodes, and area below skin.  Bartonella does not play nice.

This right here is an example of why Lyme/MSIDS patients can suffer so.  Nobody is considering the implications of Bartonella with Lyme.  

For more:  https://madisonarealymesupportgroup.com/2018/05/07/fox-news-bartonella-is-the-new-lyme-disease/

https://madisonarealymesupportgroup.com/2016/01/03/bartonella-treatment/

https://madisonarealymesupportgroup.com/2018/09/07/bartonella-infectious-endocarditis-associated-with-cryoglobulinemia-multifocal-proliferative-glomerulonephritis/

https://madisonarealymesupportgroup.com/2017/01/04/endocarditis-consider-bartonella/

https://madisonarealymesupportgroup.com/2017/05/11/bartonella-henselae-in-children-with-congenital-heart-disease/

https://madisonarealymesupportgroup.com/2018/09/20/humana-bartonellosis-perspectives-of-a-veterinary-internist/

Hotter Bodies Better at Fighting Disease

http://www.greenmedinfo.com/blog/hotter-bodies-better-fighting-disease

Hotter Bodies Better at Fighting Disease

Having a “hot body” has more benefits than ever before, thanks to new scientific findings on the role that elevated body temperature plays in helping fight infections and ward-off disease

A 2018 study examining the role that temperature plays in the body’s inflammatory response has demonstrated that the hotter our body temperature, the more effective our immune system becomes at fighting tumors, healing wounds, and fighting infections.

Researchers at the Universities of Warwick and Manchester in the UK recently published the paper entitled, Temperature regulates NF-κB dynamics and function through timing of A20 transcription,[1] in the Proceedings of the National Academy of Sciences of the USA. Acknowledging that inflammation is often accompanied by changes in body temperature, researchers sought to close the gap of information on how these phenomena may be linked.

Using an experimentation method incorporating mathematical modeling, researchers from the University’s Mathematics Institute partnered with biologists, infectious disease specialists, epidemiologists and other scientists to better understand these systemic interactions. These models were used to calculate cellular responses to inflammation, such as how small increases in body temperature affect specific genes, including keyinflammatory regulators.

Biologists focused on the actions of a protein called ‘Nuclear Factor kappa B’ (NF-κB). When inflammation markers are in the bloodstream, NF-κB proteins “switch on” by moving into and out of the nucleus of cells, turning genes on and off in response to inflammation. This cellular-signaling works on a biological clock, with cells activated for a period of time to respond to the perceived source of inflammation. A healthy NF-κB response allows the body to effectively suppress tumors and infections, and aids in rapid wound-healing. An uncontrolled NF-κB response is associated with inflammatory diseases such as psoriasis, rheumatoid arthritis, and Crohn’s disease.

Mathematical models were used to test the correlation of the rate of this NF-κB “clock” to changes in body temperature. Researchers discovered that if the body temperature is lower than normal, around 94℉, the NF-κB clock slows down. This has the effect of slowing the body’s response rate to wounds and infections. When the body temperature is higher than normal (>98.6℉), as in the case of fever, the NF-κB clock speeds up and continues to increase with each degree of uptick in body temperature. This increased physiological response to inflammation is associated with rapid wound healing, fewer and shorter infections, and even anti-cancer benefits.

Researchers correctly predicted that a protein called A20 holds a critical key in this process. When A20, the central gatekeeper in inflammation and immunity,[2] was removed from cells during experimentation, the NF-κB clock lost its correlative link with body temperature. This link helps explain why our bodies cycle through normal changes in body temperature (+/- 1.5 degrees) over the course of a 24-hour day.

Lead mathematician David Rand, Professor of Mathematics and member of the University of Warwick’s Zeeman Institute for Systems Biology and Infectious Disease Epidemiology, commented:

“The lower body temperature during sleep might provide a fascinating explanation into how shift work, jet lag or sleep disorders cause increased inflammatory disease.”

Researchers concluded that cellular response to inflammation may be “mechanistically and functionally regulated by temperature,” clearing the way for new drugs that control inflammation by more precisely targeting the A20 protein.

Professor Mike White, lead biologist from the University of Manchester, noted that these findings validate our understanding of why

“influenza and cold epidemics tend to be worse in the winter when temperatures are cooler,” and that “mice living at higher temperatures suffer less from inflammation and cancer.” Said White: “These changes may now be explained by altered immune responses at different temperatures.”

Bring the Heat to Boost Immunity

Fever is a normal part of a healthy immune response that is often met by over-reaction. Fever is produced when we come into contact with toxins, E. coli bacterium, for example, that introduce pyrogens into the bloodstream. Pyrogens are toxins that infect the body and stimulate a fever-response. The immune system identifies pyrogens as threats, alerting the hypothalamus to signal the body to generate and retain heat in the form of a fever.

Medication designed to suppress a therapeutic fevercan do more harm than good. According to Harvard Medical School, an adult has a fever when his or her temperature exceeds 100.4℉. A fever is not considered medically urgent until it exceeds 104℉,[3] at which point measures should be taken to cool the body and seek immediate medical attention.

Pyrogens signal the immune system when a dangerous toxin has entered the bloodstream. But what about microtoxins that we are exposed to everyday? Persistent organic pollutants such as chemical fertilizers from agro-runoff are in the soil, air, and water of most places in America. Heavy metals loosed from the Earth by industrial operations become airborne and seep into soil and water tables. Plasticizers like phthalates are found in umbilical cord tissue and breast milk, and in the fat cells of most Americans. Most of us don’t get a fever every time we walk outside, but we should not mistake this apparent lack of bodily reaction for a lack of bodily harm.

“The dose makes the poison,” is more than just a colloquialism; it is a chemical reality that has allowed for questionable standards for public drinking water, mass-produced foods, and air quality in the United States. Until recently, medical science had essentially discounted the dangers of low-dose toxins. Difficulty with accurate testing methods, as well as the inability to affect rapid policy and procedural change, are among the reasons why scientists had left this question largely unexplored. Thankfully, this has changed in the last decade, and not a moment too soon: recent studies show that low-dose toxins can be among the most dangerous of all chemical exposures.[4]

In a landmark study released at the end of 2017,[5] scientists found that

“widely disseminated chemicals and pollutants…are proportionately more toxic at the lowest levels of exposure,” and “we will need to achieve near-zero exposures to protect public health.”

Other recent studies have shown that microdoses can and do impact health, including increased risk of neurodegenerative diseases,[6] hormonal disturbances,[7] and increased risk of cancers.[8] Since we can’t snap our fingers and make environmental toxins go away, a diligent approach to disease prevention includes enhancing our immune system and efficiently dumping toxins on a regular basis.

Thankfully, we don’t need to become sick with fever to reap the disease-fighting advantages of a body temperature boost. There are natural ways to hack our body heat that also speed detox—and are often downright enjoyable! Whether you patronize a health club or implement a DIY solution, here are three healthful therapies that will help you turn up the heat.

Break a Sweat

Your body has a powerful, natural system for detoxifying that doesn’t require you to suffer the discomforts of being under-the-weather. All you have to do is pick your favorite exercise and break a sweat! Sweating is one of mankind’s primary mechanisms for eliminating toxins and purifying the body. Sweating naturally raises body temperature, dumps wastes, and stimulates biochemical activity, including increased circulation of blood and lymphatic fluid.

A 2011 study published in the Archives of Environmental and Contamination Toxicology, observed that dangerous metals and petrochemicals were detected in the sweat of study participants that were not seen, or were seen in differing levels, in urinalysis and blood serum tests conducted on the same patients. This finding prompted researchers to call for “sweat analysis to be considered as an additional method for monitoring bioaccumulation of toxic elements in humans.”

You can induce a sweat with intense exercise or take a more leisurely approach through sunbathing. Sunbathing raises body temperature when photons penetrate the skin, stimulating production of Vitamin D and energizing the water in our cells. UV and radiant heat make H2O’s charge, polarity, and conductivity stronger, while blood, lymph, and other body fluids become thinner. This speeds circulation, moving oxygen-rich blood in, and waste products, out. Getting a deep, purifying sweat several times per week can greatly enhance the efficiency at which our bodies remove these everyday toxins.

Sauna Therapy

Another low-impact option for increasing body temperature is sauna therapy. Saunas can be enjoyed in many forms, including traditional dry sauna, steam sauna, and infrared sauna. In a dry sauna, humidity is kept between 10-20%, with temperatures reaching as high as 185℉. Body temperatures easily reach elevated levels during sauna, and can be safely sustained for around 15-30 minutes, for most individuals.

Dry or Finnish sauna is the standard in many countries and is widely regarded as a healthful way to purify and relax the body. But the benefits of sauna extend well beyond relaxation. A 2002 study introduced twenty patients suffering from chronic heart failure to daily, 15-minute dry sauna sessions. Results showed that 17 of the 20 patients had improved vascular and cardiac function after just two weeks of sauna therapy.

Wet or steam sauna has a different host of health benefits. Steam is healing for many respiratory ailments, and can deeply penetrate sore, aching muscles. Hot tubs can reach temperatures of 104℉, and for some, is a gentler way of achieving increased body heat. According to Harvard Health, “a study of 15 men with coronary artery disease showed that 15 minutes in a hot tub produced less circulatory stress than 15 minutes on a stationary bike.” Hot tubbing has also been shown to safely lower high blood pressure.[9]

Infrared saunas use warm, infrared heaters to emit light waved that are absorbed by the surface of the skin. In a 2010 study comparing infrared and steam saunas, researchers found that the sweat from the infrared sauna contained more bismuth, cadmium, chromium, mercury, and uranium. The steam sauna caused higher levels of arsenic, aluminum, cobalt, copper, manganese, nickel, lead, tin, thallium, and zinc to be excreted.

Whatever form of sauna you choose, you can achieve an even greater immunity boost by plunging into cold water in-between bouts of heat. This quick temperature shift agitates body fluids that have become stagnant from periods of inactivity and is great for enhancing circulation.

Thermotherapy

Therapeutic heating, or thermotherapy, applies to any form of therapy in which heat is applied to achieve physical improvement or relief from symptoms. Whether it’s applying a hot water bottle to an aching muscle group or taking a hot bath with Epsom salts, thermotherapy can achieve low-level increases in body temperature, and is a useful form of easy-to-render comfort and relief from aches and pains.

Heat wraps and pads are employed to great efficacy for treating muscle spasms, herniated disks, eye pain, and other types of musculoskeletal issues. A 2002 study found that warm paraffin wax baths were useful in improving range-of-motion in sufferers of rheumatoid arthritis.[10]Objective improvements were seen in ability to pinch fingers together, improved grip strength, and reduced pain and stiffness when compared to controls after four consecutive weeks of treatment. Treatments such as these can be a useful adjunct to traditional arthritis treatment and may allay the need for habitual pain medication.

Thermotherapy isn’t limited to mundane applications like heating pads—you can also find it in-use as a space-age, laser beam used to fight cancer. Intense heat is directed via infrared laser into the eyes of cancer patients, where it effectively heats and kills retinoblastoma tumor cells that form inside the eye.[11] Other low-level laser therapies are being employed for the treatment of chronic pain[12]and arthritis, with other therapeutic uses for laser currently under development.

References

[1]http://www.pnas.org/content/early/2018/05/09/1803609115/tab-article-info

[2]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659177/

[3]https://www.health.harvard.edu/diseases-and-conditions/fever-in-adults2

[4]https://doi.org/10.1371/journal.pbio.2003066

[5]IBID

[6]https://www.sciencedirect.com/science/article/pii/S2214750015300974

[7]https://www.ncbi.nlm.nih.gov/pubmed/23867546

[8]https://www.nature.com/articles/bjc2011489

[9]https://www.health.harvard.edu/staying-healthy/saunas-and-your-health

[10]https://www.cochrane.org/CD002826/MUSKEL_thermotherapy-heat-treatment-for-treating-rheumatoid-arthritis

[11]https://www.cancer.org/cancer/retinoblastoma/treating/thermotherapy.html

[12]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137223/

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of GreenMedInfo or its staff.

 

 

 

 

Spirochete Culture Microscopy Videos: See What’s Inside You

Videos by Peter Kemp, private researcher at Private borreliosis research.

Published on Sep 26, 2018

 Approx. 2 Min

Description text in video ‘String-of-pearls’ spirochaete morphology as documented for over 100 years.

Approx. 1 Min

Cluster1

Slide culture of fingertip blood drop.

 

 

Coconut Oil Poisonous?

https://wellnessjourneys.org/2018/08/29/is-coconut-oil-a-poison-by-dr-bruce-fife-coconut-research-center/

Coconut_Clipart_Cartoon-Custom

By Dr. Bruce Fife

Coconut oil is poisonous, so claims Karin Michels, PhD, a part-time professor at Harvard TH Chan School of Public Health.

Her comments given in a talk at the University of Freiburg, Germany, sparked a media frenzy with headlines such as, “Coconut Oil is Pure Poison Harvard Professor Claims” appearing in newspapers and on the internet.

What makes Dr. Michels an authority on coconut oil? She is not a physician, or a nutritionist, or even a biologist. Her PhD is in biostatistics. Her specialty is statistics—manipulating numbers—not the study of diet or fats and oils. From her profile on the Harvard website, it appears she has never published any studies on saturated fat, let alone on coconut oil. Her comments were not based on any of her own published research, but were simply her opinion based on old, outdated theories about saturated fats.

Michels calls coconut oil “pure poison,” saying it was “one of the worst foods you can eat” because it is full of saturated fat, and “saturated fatty acids can clog your arteries.” She adds that “there is no study that proves significant health benefits of coconut oil.”

Dr. Michels makes three general claims:

  1. saturated fats cause heart disease
  2. coconut oil is a poison and one of the worst foods we could eat
  3. there are no studies that show any health benefits to coconut oil.

Let’s look at what the science actually says about each of these statements.

Saturated Fats Cause Heart Disease

There has never been a study published that has been able to show that saturated fats or coconut oil cause heart disease. The diet-heart disease hypothesis that has been popular for the past 6 decades basically states that heart disease is caused by high cholesterol. Many studies have shown that some saturated fats can raise blood cholesterol, and therefore it has be assumed that eating too much saturated fat can promote or even cause heart disease. Researchers have been trying to prove this hypothesis for over a half a century without success. In fact, many studies have seriously challenged this hypothesis and serious researchers have now moved on to studying new, more likely, causes for heart disease.

Cholesterol is no longer considered the evil villain as it was once portrayed. There are many types of cholesterol, some good and some potentially harmful. Saturated fats, and in particular coconut oil, have been shown to raise HDL, the good cholesterol, that has been shown to protect against heart disease. The ratio of total cholesterol to HDL cholesterol is considered one of the most accurate and reliable indicators of heart disease risk. Coconut oil raises HDL, which lowers the cholesterol ratio, thus lowering the risk of heart disease.1

It is apparent that Dr. Michels has not kept up with the current science on coconut oil or fats and oils in general. Earlier this year researchers at the University of Cambridge School of Clinical Medicine published a study on the relationship between coconut oil and heart disease risk. The researchers compared the effects of coconut oil with butter and olive oil. Butter was chosen to represent a commonly used highly saturated animal fat and extra virgin olive oil was chosen as it is generally regarded as one of, if not the healthiest of fats. The study involved 96 participants who were assigned to consume 50 mg (about 3 tablespoons) of one of each of the three oils daily for 4 weeks as a part of their ordinary diet. The researchers found that coconut oil dramatically raises the protective HDL cholesterol without affecting the LDL or so-called bad cholesterol. Coconut oil lowered the cholesterol ratio, and the risk of heart disease, more than either of the other two fats, indicating that it is even more heart-friendly than extra virgin olive oil.2

In recent years numerous studies have exonerated saturated fat as a cause of heart disease and put to rest the outdated diet-heart disease hypothesis. Last year the Lancet, one of the most prestigious medical journals in the world, published a study involving a team of 37 researchers from 18 countries. They gathered data on 135,000 subjects to evaluate heart disease risk in relation to fat intake. They discovered that fat consumption protected against heart disease and increased lifespan. Those people who cut back on fats, including saturated fat, had far shorter lives than those who ate coconut oil, butter, cheese, and meats. Consuming high levels of all fats, cut early death rates by up to 23 percent. The researchers stated that they found no correlation between saturated fat consumption and cardiovascular disease and that current dietary restrictions on saturated fat should be revised.3

This isn’t the only study in recent years that has called for a revision on the recommendation to restrict saturated fats. A study published in the American Journal of Clinical Nutrition a year earlier investigated whether dietary saturated fat was associated with ischemic heart disease. The study involved 35,597 participants. The researchers also concluded that high saturated fat intake was not associated with increased risk of ischemic heart disease.4

In 2010 a groundbreaking study was published clearly showing that saturated fats do not cause heart disease. The study published in the American Journal of Clinical Nutrition analyzed all the previous studies with data for dietary saturated fat intakes and the risk of cardiovascular disease. This meta-analysis combined the data from 21 previously published studies, involving over 347,000 subjects. The study showed that there was no connection between saturated fat consumption and heart disease. Those people who ate the greatest amount of saturated fat where no more likely to suffer a heart attack or stroke than those who ate the least. No matter how much saturated fat one ate, the incidence of heart disease was not affected. This was the most complete review of the medical research on saturated fat ever done up to this time.5

Four years later, a different group of researchers from Cambridge University published another meta-analysis. This time the researchers combined the data from 72 previously published studies involving more than 600,000 participants from 18 countries. The researchers basically combined all the highest quality studies on fats and diet that had been done for the past several decades and analyzed them together. The results confirmed the previous meta-analysis—there is no connection between saturated fat intake and heart disease.6

The studies are clear, neither saturated fat nor coconut oil cause or even promote heart disease. Because they raise good HDL cholesterol and lower the cholesterol ratio, if anything, they help to protect against it.

Coconut Oil Is a Poison and One of the Worst Foods We Could Eat

Dr. Michels calls coconut oil a “pure poison.” She claims it is not just a poison, but a “pure” poison; the connotation is, that it is extremely dangerous at even the smallest dosage. What is a poison? According to the English Oxford Living Dictionary, poison is defined as, “A substance that is capable of causing the illness or death of a living organism when introduced or absorbed.” Does coconut oil fit this definition? Not hardly.

Coconut oil has been a major part of the diet of millions of people for thousands of years. In all that time it has never been known to cause any illness or kill anyone. On the contrary, there are many plants that are poisonous such as hemlock, belladonna (deadly nightshade), and death cap mushrooms. Consuming any of them, even in small amounts, will bring about sudden illness and quick death. Coconut oil, on the other hand, can be consumed daily in relatively large quantities without any ill effect. I know some people who consume as much as 12 tablespoons (180 ml) a day and are in excellent health.

According the United States Food and Drug Administration (FDA) coconut oil is perfectly harmless. It is included among the FDA’s exclusive GRAS (Generally Regarded as Safe) list of food substances. To be included on this list requires rigorous testing to confirm that the item is safe. Coconut oil is given a GRAS classification of “1,” which is the highest or safest category within the GRAS list. According to the FDA this means that all available studies and historical data have shown that there is “no evidence” that shows or even “suggests” that coconut oil is harmful in any way.7

It is ironic that Dr. Michels calls coconut oil a poison, because it has proven to be not only harmless, but highly effective in saving the lives of people who have ingested actual poisons. The medical literature has described numerous instances in which coconut oil has been used in hospital settings as an antidote to otherwise fatal poisonings. For instance, the use of coconut oil has become a routine practice in some hospitals in the treatment of aluminum phosphide poisoning.8 Aluminum phosphide is a common poison used for rodent control. There is no other known antidote and poisonings are almost always fatal unless treated with coconut oil.

Using coconut oil to nullify the effects of poisons is not that unusual. Researchers have known for many years about the detoxifying properties of coconut oil. Numerous animal studies have shown that coconut oil blocks the deleterious effects of a number of different chemical toxins. Coconut oil has been shown to alleviate the effects of at least 36 known toxins ranging from industrial solvents to aflatoxin.9

Calling coconut oil a pure poison only illustrates Dr. Michels’ lack of knowledge about coconut oil, which makes anything she says about it totally unreliable.

There Are No Studies That Show Any Health Benefits to Coconut Oil

One of the most common arguments given in an attempt to discredit coconut oil is to claim that there is no evidence proving coconut oil has any health benefits. When a doctor or professor makes this statement, he or she is inferring that there are no studies to support the use of coconut oil as a healthy fat. They are counting on the listener to take their word on this simply because they are considered an expert. In reality, what they are doing is exposing their own ignorance and lack of knowledge on the subject.

When someone makes this type of statement it means they have not bothered to make even the slightest effort to find the facts. If they had, they would have found an abundance of information and research on coconut oil describing its many health benefits. Currently, there are over 10,000 studies on coconut oil listed in the medical literature. Most of these studies can be easily accessed on the internet.

If you go to my website,www.coconutresearchcenter.org and look under the heading “Medical Research,” you will find a listing of hundreds of studies. Here you will find references to an abundance of published studies showing the therapeutic or beneficial effects of coconut oil on cardiovascular health, immune function, cancer, diabetes, liver and kidney health, digestive function, weight management, and much more. To say that there is no evidence for the health benefits of coconut oil is totally wrong and indicates that the speaker is either woefully ignorant, too lazy to do any research, or lying.

If you want to know the truth about saturated fats and coconut oil you should not listen to professors who have no idea what they are talking about, instead listen to researchers who have actually researched the topic. One of the reasons why Dr. Michels’ comments received such notoriety is because of her association with Harvard. Being a Harvard professor gives a person some air of authority. However, there are other Harvard professors who are far more qualified than Dr. Michels on this subject, who have studied and published works on the health effects of coconut oil. One group of Harvard researchers that includes George L. Blackburn, MD, PhD, Edward Mascioli, MD, and Vigan K. Babyan, PhD state,

“Coconut oil has an important medical role to play in nutrition, metabolism, and health care. Indeed, properly formulated and utilized, coconut oil may be the preferred vegetable oil in our diet and the special hospital foods used promoting patient recovery.”

These researchers made this statement after having spent years studying the health effects of coconut oil and other fats. Their comments hold far more authority than a biostatistician who apparently has never even bothered to do even an internet search on the subject.

References

  1. Assuncao, ML, et al. Effects of dietary coconut oil on the biochemical and anthropometric profiles of women presenting abdominal obesity. Lipids 2009;44:593-601.
  2. Khaw, KT, et al. Randomised trial of coconut oil, olive oil or butter on blood lipids and other cardiovascular risk factors in healthy men and women. BMJ Open 2018;8:e020167.
  3. Dehghan, M, et al. Associations of fats and carbohydrate intake with cardiovascular disease and mortality in 18 countries from five continents (PURE): a prospective cohort study. Lancet 2017;390:2050-2062.
  4. Praagman, J, et al. The association between dietary saturated fatty acids and ischemic heart disease depends on the type and source of fatty acid in the European Prospective Investigation into Cancer and Nutrition-Netherlands cohort. Am J Clin Nutr 2016;103:356-365.
  5. Siri-Tarino, PW, et al. Meta-analysis of prospective cohort studies evaluating the association of saturated fat with cardiovascular disease. Am J Clin Nutr 2010;91:535-546.
  6. Chowdhury, R, et al. Association of dietary, circulating, and supplement fatty acids with coronary risk: a systematic review and meta-analysis. Ann Intern Med 2014;160:398-406.
  7. https://www.fda.gov/Food/IngredientsPackagingLabeling/GRAS/SCOGS/default.htm.
  8. Singh Baiwa, SJ, et al. Management of celphos poisoning with a novel intervention: a ray of hope in the darkest of clouds. Anesth Essays Res 2010;4:20-24.
  9. Fife, B. Ketone Therapy: The Ketogenic Cleanse and Anti-Aging Diet. Piccadilly Books, Ltd.: Colorado Springs, CO; 2017.

_________________

Information on Dr. Fife here:  http://www.faim.org/dr-bruce-fife

Dr. Bruce Fife is a certified nutritionist and naturopathic physician. He is the author of more than 20 books including The Coconut Oil Miracle, The New Arthritis Cure, and Stop Alzheimer’s Now!: How to Prevent and Reverse Dementia, Parkinson’s, ALS, Multiple Sclerosis, and Other Neurodegenerative Disorders. He serves as the director of the Coconut Research Center in Colorado.

News story on Michels here:  https://www.businessinsider.com/harvard-speaker-busts-coconut-oil-health-myth-calling-it-pure-poison-2018-8

 

 

 

Road Kill Provides Insight into Tick-borne Pathogens

https://www.ncbi.nlm.nih.gov/m/pubmed/30230270/

Road-killed mammals provide insight into tick-borne bacterial pathogen communities within urban habitats.

Szekeres S, et al. Transbound Emerg Dis. 2018.

Abstract

Small and medium-sized mammals play an important role in the life cycle of tick-borne pathogens in urban habitats. Our aim was to apply the general protocol, DAMA (documentation-assessment-monitoring-action), which is an integrated proposal to build a proactive capacity to understand, anticipate, and respond to the outcomes of accelerating environmental change. Here we tested whether road killed carcasses in urban areas are useful sources of tissue and parasite samples to investigate these species’ contribution to the epidemiology of vector-borne diseases.

We collected 29 road-killed and 6 carcasses with different causes of mortality (23 northern white-breasted hedgehogs and twelve from seven other mammal species) mainly from Budapest, Hungary. We used quantitative and conventional PCRs to determine pathogens in 90 collected tissues (52 from hedgehogs; 38 from other species) and 417 ticks that were only found on hedgehogs.

Tissue samples revealed a wide range of bacteria including human zoonotic pathogens identified as Anaplasma phagocytophilum ecotype I, Borrelia afzelii, B. spielmanii, B. miyamotoi, Rickettsia helvetica and Bartonella species. Among the twenty-three collected hedgehog carcasses 17 (74%) were infected with A. phagocytophilum, six (26%) with B. burgdorferi s.l., 12 (52%) with R. helvetica and 15 (65%) with Rickettsia sp. Furthermore, we report the first detection of Rickettsia sp. infection in European moles and lesser weasel and R. helvetica in stone marten. Through sequencing B. afzelii, R. helvetica, R. monacensis and A. phagocytophilum ecotype I were identified in the ticks removed from the carcasses. We showed that road-killed urban mammal species are exposed to multiple tick-borne pathogens but further studies have to clarify whether they, in fact, also have a role in their maintenance and spread. Our study also demonstrates that roadkill can be used in the risk assessment of potential human infection and in the implementation of the DAMA protocol.