Archive for the ‘Pain Management’ Category

The Lyme Disease + Vagus Nerve Connection

https://rawlsmd.com/health-articles/the-lyme-disease-vagus-nerve-connection

The Lyme Disease + Vagus Nerve Connection

The Lyme Disease + Vagus Nerve Connection

by Jenny Lelwica Buttaccio
Posted 7/22/20

Take a moment to consider: How often does your intuition play a role in how you decide to treat your Lyme disease? For instance, maybe you decided not to pursue a certain healing modality despite rave reviews because you felt deep in your belly that it wasn’t right for you. Or, perhaps you were drawn to a particular therapeutic intervention (i.e. herbal therapy, detoxification, a specific healthcare provider) because something seemed “right” about the decision.

Most of us have had these types of “gut feelings” about some aspect of our lives. Although these feelings are attributed to your gut, they’re actually the interaction between your brain and the vagus nerve. The longest and most elaborate cranial nerve in your body, the vagus nerve is a primary pathway by which the sympathetic and parasympathetic nervous systems can be balanced.

So what does it have to do with Lyme disease?

People with chronic Lyme disease often report feeling hyper, irritable, and anxious from time to time — evidence of a nervous system that’s shifted into high gear. To cultivate conditions that are more conducive to healing, the overworked nervous system may need to be reset. One way to do this is by stimulating the vagus nerve so that the body can reach a greater state of tranquility.

Here, we’ll examine the vagus nerve, its role in chronic illness, and what you can do to improve its function and restore your health.

Vagus Nerve Basics

There are 12 pairs of cranial nerves in the body. Each originates from the brain and has a specific set of tasks to perform that affect sensory and motor function. Each nerve has a Roman numeral from I through XII assigned to it. The vagus nerve, for example, is the 10th cranial nerve and corresponds to the Roman numeral X.

Vagus is a Latin word that means “wandering,” and indeed, this intricate cranial nerve lives up to its name because it wanders throughout the body. It acts as an information superhighway from your brain, through the neck and thorax, and stops in the abdomen.

While some nerves influence only the senses or only movement, the vagus nerve is unique in that it has an impact on both. The primary functions of the vagus nerve include:

  • Providing sensory input to the throat, lungs, heart, and digestive tract
  • Having a minor role in the sensation of taste in the back mouth
  • Supplying movement information to neck muscles for speech and swallowing
  • Regulating mechanical functions of the respiratory tract, heart rate, and gastrointestinal tract
  • Modulating the response of the immune system
  • Influencing mood

Additionally, the vagus nerve is a crucial component of your parasympathetic nervous system, the relaxing side of the nervous system, which helps bring your body back to a state of calm after a stressful period or event. However, the challenges of living life with Lyme or Lyme coinfections like Babesia and Bartonella can disrupt the communication to and from your vagus nerve, activating your sympathetic nervous system.

Sick woman sitting on the sofa in the living room

“The stress associated with being chronically ill sends the sympathetic nervous system, the part of the nervous system associated with the ‘fight-or-flight’ response, into overdrive,” says Dr. Bill Rawls, Medical Director of RawlsMD and Vital Plan. “Sympathetic overactivity releases stimulating chemicals like norepinephrine and dopamine, which can leave you feeling wired, tired, and anxious.”

The flight-or-fight response is critical when our circumstances demand a high state of alertness. But prolonged periods of stress can hinder sleep, recovery, repair of tissues, and more — the exact opposite of the resting state brought on by the vagus nerve.

“If you feel revved up all the time, you’ve got adrenaline surging through your system, and it makes your system very fragile,” says Dr. Rawls. So how do we best support the function of our parasympathetic nervous system and vagus nerve? The answer lies in the biological process carried out by the vagus nerve called vagal tone.

Vagal Tone and 4 Ways to Bolster It

The concept of vagal tone has seen a recent surge in interest among integrative health and wellness professionals, but some of the first-known research on the subject dates back to the early 1900s. By increasing vagal tone, your body is better equipped to tap into the calming and reparative mechanisms of the parasympathetic nervous system when stress ensues.

Your vagus nerve is involved in many different bodily processes, so it’s essential to understand how to get out of the chronic flight-or-fight mode. Let’s take a closer look at some options.

1. Get a Daily Dose of Cold.

When you think about experiencing cold temperatures, vagus nerve stimulation probably doesn’t come to the forefront of your mind (heavy layers, coats, and thick blankets are more like it). However, research indicates exposure to cold may indeed improve vagal tone.

Upon initial introduction to cold weather, study participants demonstrated an increase in activity of the sympathetic nervous system, as measured by their cardiovascular function. However, once the participants acclimated to the temperature, their parasympathetic activity rose, suggesting that adapting to the cold may balance the response of the vagus nerve.

Cold shower interval improve vagal tone

To get your daily dose of cold and stimulate the vagus nerve, consider alternating 60-second intervals of hot water, directly followed by cold water when taking a shower. Then, repeat the process two or three times. If you need to calm down in a pinch, try splashing some cool water from the sink on your face. The quick rush of cold may be just enough to produce a desired calming result.

2. Improve the Health of Your Microbiome.

“The microbiome is the sum of all the microbes that inhabit the body, including normal flora that typically causes no harm as well as potential disease-causing pathogens,” says Dr. Rawls. “The microbiome is vast and more complex than anyone could have ever imagined.” Though the science of this expansive micro-ecosystem continues to advance, research — like that found in the Journal of Medicinal Food — suggests a sea of possibilities for how the gut and brain interact with one another.

The main mode of communication? It’s the vagus nerve, which gives and receives information from your gut, via a two-way, or bidirectional, throughway called the gut-brain axis. Additionally, the vagus nerve facilitates the production of relaxing chemicals like serotonin and GABA in the brain, slows breathing, reduces heart rate and blood pressure, decreases inflammation, and promotes healing.

Gut bacteria can impact the vagus nerve because the microbes stimulate nerve impulses that send signals to the brain, affecting such functions as sleep, reactivity to stress, cognition, and more. When the gut flora is healthy, there’s a more harmonious relationship among the types of signals being sent along the lengthy cranial nerve. However, the persistent symptoms of Lyme disease can fuel chronic stress, altering your body’s normal microbial load and, along with it, the signals they send.

Stealth microbes inflammation body brain

Additionally, “Stealth microbes that are deeply embedded in tissues generate low-grade inflammation throughout the body and the brain,” says Dr. Rawls. The shift in the body’s terrain may trigger an overproduction of excitatory chemicals like adrenaline, norephinepherine, and dopamine.

But there is hope to strengthen the microbiome and improve communication through the vagus nerve. Dr. Rawls suggests herbs as an efficient, natural solution: “Taking the appropriate herbs provides phytochemicals that work to restore the microbiome and support vagus nerve function.” His top recommendations for gut-balancing herbs include:

  • Berberine: An herb with substantial anti-microbial properties, berberine helps manage the gut microflora.
  • Slippery elm: Due to its ability to form a protective film in the gut, slippery elm soothes irritation in the mucosal lining and keeps foreign substances out of the bloodstream.
  • Dandelion root: Known as a bitter herb, dandelion root activates bitter receptors throughout our GI tract, releasing the saliva, enzymes, and bile we need to break down our food.
  • Andrographis: Originating from India, andrographis has antiviral, antibacterial, and antiparasitic qualities. It helps to restore the GI tract and is a powerful anti-inflammatory herb.

3. Practice Calming Breathing Exercises.

Since the vagus nerve assists in regulating your respiration and heart rate, one way to improve vagal tone is by engaging in breathing exercises. Research has shown that practicing slow breaths lessens the activity of the sympathetic nervous system and boosts parasympathetic functions. In contrast, rapid breathing — something we tend to do when we’re on edge — doesn’t provide the same benefits.

Activities like meditation, yoga, tai chi, and qigong can facilitate a slow breathing practice.

Wide angle view at modern young woman enjoying breathing exercises while meditating at home, copy space

But if you can’t get to a class, belly breathing is an excellent alternative, and it’s easy to do. Here’s how to get started:

  1. Sit or lie in a comfortable position.
  2. Place one hand on your belly and the other hand over your heart.
  3. Breathe in deeply through your nose to the count of 4, allowing your belly to move your hand out or up. Note that your chest shouldn’t move with the breath.
  4. Exhale for 4 counts. Notice how your belly lowers back to the starting position.
  5. Repeat until you feel an increased sense of calm.

4. Hum a Tune.

Did you know that humming to yourself may be a healthy habit? That’s because the vagus nerve runs through your throat and provides sensory input to the ear. The act of humming offers a mechanical way to stimulate the vagus nerve and lessen heart rate and respirations, which may be the reason why many people find humming to be soothing to them.

Humming singing mantra improve vagal tone

Other vocal activities such as repeating a mantra or singing may improve vagal tone and promote a more peaceful state of wellbeing as well. So, go ahead — pick your favorite tune and start humming, or just wing it!

The Bottom Line

The key to improving vagal tone is to be on the lookout for factors that raise adrenaline during the day and, when levels are rising in the absence of a true emergency, introduce activities that curb the excessive fight-or-flight response, says Dr. Rawls. Though not a cure-all, when combined with a comprehensive natural protocol and a nutrient-dense diet, increasing vagal tone is a low-cost and simple tool to maximize healing and restoration.

Dr. Rawls is a physician who overcame Lyme disease through natural herbal therapy. You can learn more about Lyme disease in Dr. Rawls’ new best selling book, Unlocking Lyme.
You can also learn about Dr. Rawls’ personal journey in overcoming Lyme disease and fibromyalgia in his popular blog post, My Chronic Lyme Journey.

REFERENCES
1. Bonaz B, Bazin T, Pellissier S. The Vagus Nerve at the Interface of the Microbiota-Gut-Brain Axis. Front Neurosci. 2018;12:49. Published 2018 Feb 7. doi: 10.3389/fnins.2018.00049
2. Breit S, Kupferberg A, Rogler G, Hasler G. Vagus Nerve as Modulator of the Brain-Gut Axis in Psychiatric and Inflammatory Disorders. Front Psychiatry. 2018;9:44. Published 2018 Mar 13. doi: 10.3389/fpsyt.2018.00044
3. Clancy JA, Deuchars SA, Deuchars J. The wonders of the Wanderer. Exp Physiol. 2013;98(1):38-45. doi: 10.1113/expphysiol.2012.064543
4. Mäkinen TM, Mäntysaari M, Pääkkönen T, et al. Autonomic nervous function during whole-body cold exposure before and after cold acclimation. Aviat Space Environ Med. 2008;79(9):875-882. doi: 10.3357/asem.2235.2008
5. Pal GK, Velkumary S, Madanmohan. Effect of short-term practice of breathing exercises on autonomic functions in normal human volunteers. Indian J Med Res. 2004;120(2):115-121
6. Vickhoff B, Malmgren H, Aström R, et al. Music structure determines heart rate variability of singers [published correction appears in Front Psychol. 2013 Sep 05;4:599]. Front Psychol. 2013;4:334. Published 2013 Jul 9. doi: 10.3389/fpsyg.2013.00334

_______________________

For more:  https://www.aans.org/Patients/Neurosurgical-Conditions-and-Treatments/Vagus-Nerve-Stimulation

https://www.psychologytoday.com/us/blog/the-athletes-way/201607/vagus-nerve-stimulation-dramatically-reduces-inflammation

https://www.mayoclinic.org/tests-procedures/vagus-nerve-stimulation/about

Act Now! FDA Shuts Down Natural Pain Options

https://healthimpactnews.com/2020/fda-shuts-down-natural-pain-options/

FDA Shuts Down Natural Pain Options

Dec. 12, 2020

by Alliance for Natural Health

FDA-approved pain medicines are dangerous, but the government is systematically attacking safer, non-addictive natural treatments. Action Alert!

A recent study in Switzerland found that acetaminophen poisoning increased by 40% following the approval of 1,000mg doses. This is just the latest data to indicate the public health problems caused by this commonly used pain drug, which is the active ingredient in Tylenol.

Despite the dangers of FDA-approved pain drugs, the federal government aggressively attacks and censors natural pain medicines like homeopathic treatments, CBD, medical foods, and supplements. This needless suffering must end.

We’ve written for years about the dangers of acetaminophen. It is the most commonly prescribed class of drugs despite causing 50 percent of all liver failure in the US. According to the FDA’s adverse event database, acetaminophen has caused more than 100,000 adverse events and more than 78,000 serious adverse events, including 24,000 deaths. It has also been linked to asthma and hearing loss.

Overdoses involving opioids killed nearly 47,000 people in 2018 alone.

Now consider the federal government’s approach to natural pain medicines. The FDA essentially banned all injectable homeopathic medicines, which includes Traumeel, a prescription-only homeopathic medicine for pain with an extremely robust safety profile.

Previously, the FDA went after Limbrel, a medical food for the treatment of osteoarthritis. In a letter to Primus, the FDA stated that 194 adverse event reports for Limbrel were received between 2007 and 2017—about 20 a year.

Then, of course, there’s CBD. The federal government’s approach to CBD right now is frankly a mess, and we’ve sifted through the details in previous coverage. In short, hemp and its derivatives have been legalized at the federal level, but FDA laws still apply to products containing hemp, such as supplements, lotions, cosmetics, etc. Since 2018, the FDA has been trying to figure out how it will treat these products. Recall, too, that the agency has approved a CBD drug, and according to FDA rules, this means that CBD cannot legally be sold as a supplement.

We ultimately don’t know how the FDA will treat CBD supplements. If history provides any clues, the FDA will protect the drug-approval process and ban CBD supplements. To add to the confusion, Congress is directing the FDA to release an interim policy (called a policy of enforcement discretion) explaining how it will treat CBD products in the marketplace as the agency develops its final regulatory framework. Will the FDA release an interim policy that allows CBD supplements for the time being before banning them outright when a final policy is released? We just don’t know, but we should assume that the FDA will not do the right thing, especially when Big Pharma profits are at stake.

It is unconscionable, but unsurprising, that the FDA would reduce access to safe, non-addictive alternatives to dangerous opioid drugs that killed 30,000 people in 2018 alone. We’ve also seen basic information on natural health censored to protect drug industry profits during the COVID-19 pandemic. This cronyism has to stop.

Action Alert! Write to Congress and the FDA, telling them to issue a policy of enforcement discretion that protects consumer access to hemp-derived CBD supplements at therapeutic levels and full-spectrum hemp oil. Please send your message immediately. By sending this message, you will also be supporting our petition to ungag doctors so that they can share with patients the benefits of supplements and natural treatments for COVID.


____________________

**Comment**

Our government shuts down anything that competes with its own lucrative products.

For more:

Looking Back on Her Teen Years of Lyme-Related Pain. (Life’s Better Now!)

https://www.lymedisease.org/teen-lyme-pain-lifes-better-now/

Looking back on her teen years of Lyme-related pain. (Life’s better now!)

The Social Consequences of Chronic Pain

https://www.painnewsnetwork.org/stories/2020/9/12/the-social-consequences-of-chronic-pain

The Social Consequences of Chronic Pain

iu-10

By Ann Marie Gaudon, PNN Columnist

When someone suffers acute pain from an accident or injury, a positive consequence is that it evokes care and compassion from others. However, when that pain becomes chronic, you don’t often receive flowers, cooked meals and offers of help. Your social connections may suffer, too.

That’s not a small issue for pain patients. A 2008 study found that maintaining social activities are just as important for people in pain as many of the physical and psychological consequences of chronic pain.

Let’s take a look at a short list of five ways that chronic pain challenges the maintenance of social relationships.  (See link for article)

_____________________

**Comment**

An unfortunate truth not only experienced by pain patients but any chronically ill person.

For more:  https://madisonarealymesupportgroup.com/2020/06/26/why-social-distancing-should-not-be-the-new-normal/

https://madisonarealymesupportgroup.com/2020/09/02/10-years-of-headaches-vertigo-and-other-pains-dismissed-as-depression/

https://madisonarealymesupportgroup.com/2020/03/12/no-rash-no-fever-so-much-pain-the-case-of-illy-jaffers-painful-year/

https://madisonarealymesupportgroup.com/2020/08/13/ldn-for-pain-autoimmune-disorders-cancer-and-lyme-msids/

https://madisonarealymesupportgroup.com/2020/02/23/testosterone-replacement-in-chronic-pain-patients/

New Guidelines Issued on Medical Cannabis

https://www.medpagetoday.com/meetingcoverage/painweek/88593

New Guidelines Issued on Medical Cannabis for Chronic Pain

Shutterstock

— International task force shares recommendations for dosing, administering

Chronic pain patients can be treated with medical cannabis following one of three protocols based on patient characteristics, according to an international task force at the virtual PAINWeek meeting.  (See link for article)

__________________

Among their recommendations:

  • Treat the majority of patients along the “routine” scale. This means starting patients with 5 mg of cannabidiol (CBD) twice daily. Tetrahydrocannabinol (THC) should only be introduced if patients do not respond to at least 40 mg of CBD daily, starting with 2.5-mg daily THC doses. THC doses should be capped at 40 mg daily.
  • Frail and elderly patients, and those with severe co-morbidity or polypharmacy should be treated via a conservative route. This means starting the THC dosses at 1 mg daily and titrating up the THC more slowly.
  • Patients suffering from severe pain and those who have significant prior cannabis consumption can follow the rapid protocol. This mean starting with a CBD-THC balanced dose of between 2.5-5 mg per each compound once or twice daily.
A task force member admitted there is a major barrier to overcome due to a knowledge gap regarding medical cannabis.