Archive for the ‘Ehrlichiosis’ Category

First Longhorned Tick Confirmed in Arkansas

http://www.4029tv.com/article/first-longhorned-tick-confirmed-in-arkansas/21274301  (News Video here)

First Longhorned Tick confirmed in Arkansas

The USDA confirmed the presence of the Longhorned Tick in Arkansas for the first time.

The tick came from a dog in Benton County, according to the Arkansas Agriculture Department.

The Longhorned Tick is an exotic East Asian tick associated with bacterial and viral disease of both humans and animals. The USDA considers it a serious threat to livestock.

The tick is also believed to cause diseases in humans, including severe fever with thrombocytopenia syndrome. That disease was described in a 2014 CDC dispatch as “a newly emerging infectious disease.”

Multiorgan failure occurs in severe cases, and 6%-30% of case-patients die,” according to the dispatch.

The Longhorned Tick was first confirmed to be in the United States in November 2017, when a specimen was identified in New Jersey. It has also been found in Virginia and West Virginia.

Longhorned Ticks are very small and resemble tiny spiders. The Arkansas Agriculture Department warns they can easily go unnoticed on animals and people.

The department asks that animal owners, veterinarians and farmers notify the Arkansas Agriculture Department if they notice unusual ticks or ticks that occur in large numbers on a single animal.

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**Comment**

The spread of the “tick from hell” has begun.  The reason we need to take note of this particular tick:  https://madisonarealymesupportgroup.com/2018/03/01/asian-ticks-mysteriously-turn-up-in-new-jersey/

 

  1. IT CLONES ITSELF & MULTIPLIES QUICKLY…..
  2. It can drain cattle of their blood:  https://madisonarealymesupportgroup.com/2018/03/12/asian-tick-found-in-new-jersey-can-kill-cattle-by-draining-them-of-blood/
  3. It spreads SFTS (sever fever with thrombocytopenia syndrome), “an emerging hemorrhagic fever,” causing fever, fatigue, headache, nausea, muscle pain, diarrhea, vomiting, abdominal pain, disease of the lymph nodes, and conjunctival congestion, but the potential impact of this tick on tickborne illness is not yet known. In other parts of the world, this Longhorned tick, also called the East Asian or bush tick, has been associated with several tickborne diseases, such as spotted fever rickettsioses, Anaplasma, Ehrlichia, and Borrelia, the causative agent of Lyme Disease.
  4. A top ecologist wonders if infection by this tick has gone undetected in the past.
  5. There isn’t a systematic national method to look for invasive ticks.
  6. It’s quickly showing up in other states:  https://madisonarealymesupportgroup.com/2018/05/26/tick-from-hell-now-sited-in-west-virginia/
  7. It survives cold temps:  https://madisonarealymesupportgroup.com/2018/04/21/ticks-from-hell-survived-the-winter/  (Again, the spread infection has ZIPPO to do with climate change)

For a 2016 literature review on SFTS:  http://infectious-diseases-and-treatment.imedpub.com/research-advances-on-epidemiology-of-severefever-with-thrombocytopenia-syndrome-asystematic-review-of-the-literature.php?aid=17986

Although the clinical symptoms of SFTS and HGA are similar to each other, but the treatment methods of the two diseases are totally different. Doctors notice that the biggest difference between the clinical symptom of SFTS and HGA is that SFTS patients generally without skin rash, the dermorrhagia is also not seriously, and few massive hemorrhage cases were reported [23]. It is also reported that SFTS patients had gastrointestinal symptoms, such as nausea, vomiting, and diarrhea, which are rarely observed in HGA patients [2]. So these differences can be used as the auxiliary basis of differential diagnosis.

At present, there is still no specific vaccine or antiviral therapy for SFTSV infection. Supportive treatment, including plasma, platelet, granulocyte colony stimulating factor (GCSF), recombinant human interleukin 11, and gamma globulin is the most essential part of case treatment [44]. Meanwhile, some measures were taken to maintain water, electrolyte balance and treat complications are also very important.

Ribavirin is reported to be effective for treating Crimean-Congo Hemorrhagic Fever (CCHF) infections and hemorrhagic fever with renal syndrome, but it is still inadequate to judge the effect of ribavirin on SFTS patients because of the study limitation without adequate parameters were investigated [45]. Host immune responses play an important role in determining the severity and clinical outcome in patients with infection by SFTSV.

For Viral treatment options:  https://madisonarealymesupportgroup.com/2016/03/28/combating-viruses/

 

Where Ticks Are and What They Carry – Science Conversation With Dr. Cameron

http://danielcameronmd.com/lyme-disease-science-conversation-ticks-diseases-they-carry/  Approx. 50 Min

Dr. Daniel Cameron, a leading Lyme disease expert, discusses where are the ticks and what are the diseases they carry.

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**Comment**

The word is finally getting out.  TICKS ARE EVERYWHERE!

Beaches:  https://madisonarealymesupportgroup.com/2018/06/07/ticks-on-beaches/

Rocks and picnic benches:  https://madisonarealymesupportgroup.com/2017/03/13/ticks-found-on-rocks/

Caves:  https://madisonarealymesupportgroup.com/2018/04/23/tick-borne-relapsing-fever-found-in-austin-texas-caves/, and https://madisonarealymesupportgroup.com/2017/10/27/israeli-kids-get-lyme-disease-from-ticks-in-caves/

Birds:  https://madisonarealymesupportgroup.com/2017/08/17/of-birds-and-ticks/

California:  https://madisonarealymesupportgroup.com/2018/05/19/infected-ticks-in-california-its-complicated/

In the South:  https://madisonarealymesupportgroup.com/2018/05/31/no-lyme-in-the-south-guess-again/, and https://madisonarealymesupportgroup.com/2017/10/06/remembering-dr-masters-the-rebel-for-lyme-patients-who-took-on-the-cdc-single-handedly/, and https://madisonarealymesupportgroup.com/2017/03/02/hold-the-press-arkansas-has-lyme/

Southern Hemisphere:  https://madisonarealymesupportgroup.com/2018/02/06/lyme-in-the-southern-hemisphere-sexual-transmission/

Australia:  https://madisonarealymesupportgroup.com/2016/11/03/ld-not-in-australia-here-we-go-again/

And everywhere else…..

Remember, there are 300 strains and counting of Borrelia worldwide and 100 strains and counting in the U.S.  Current CDC two-tiered testing tests for ONE strain!  Do the math….

For more:  https://madisonarealymesupportgroup.com/2018/05/27/study-conforms-permethrin-causes-ticks-to-drop-off-clothing/

https://madisonarealymesupportgroup.com/2018/06/06/mc-bugg-z/

 

 

 

 

NYC Issues Tick-borne Disease Advisory

http://www1.nyc.gov/assets/doh/downloads/pdf/han/advisory/2018/advisory8-tickborne-disease.pdf

NEW YORK CITY DEPARTMENT OF HEALTH AND MENTAL HYGIENE

Mary T. Bassett, MD, MPH

Commissioner

2018 DOHMH Advisory #8: Tickborne Disease Advisory

Please share with your colleagues in Internal and Family Medicine, Pediatrics, Infectious Disease, Infection Control, Laboratory Medicine, Hematology, Cardiology, Neurology, Rheumatology, Critical Care and Emergency Medicine.

  •   Tickborne diseases, with the exception of Rocky Mountain spotted fever (RMSF), are associated primarily with travel outside of New York City (NYC). Locally acquired cases of Lyme disease and babesiosis continue to be reported from Staten Island and smaller numbers have been reported from the Bronx.
  •   Isolated cases of locally acquired anaplasmosis and ehrlichiosis have also been reported from Staten Island.
  •   The following tickborne diseases are reportable in NYC: Lyme disease, RMSF, babesiosis, anaplasmosis, ehrlichiosis, and Powassan disease.
  •   Refer to the Reference Manual for Physicians on Tickborne Diseases in the New York City Area for extensive details and guidance on identification, diagnosis, treatment and prevention available at: http://www1.nyc.gov/assets/doh/downloads/pdf/ehs/tick-borne-dx-physician.pdf. Call 311 to order copies.

    May 30, 2018 Dear Colleagues,

    New York City (NYC) clinicians should be on the alert for patients with tickborne diseases. This advisory presents key epidemiologic findings regarding reportable tickborne diseases in NYC and reminds clinicians of reporting requirements. Please refer to the revised 3rd edition of the Reference Manual for Physicians on Tickborne Diseases in the New York City Area for details and guidance on identification, diagnosis, treatment and prevention available at: http://www1.nyc.gov/assets/doh/downloads/pdf/ehs/tick-borne-dx-physician.pdf or call 311 to order copies.

    Recent travel to upstate NY, Long Island, and other parts of New England should prompt consideration of tickborne diseases. A history of a tick bite is not a prerequisite for considering tickborne diseases for patients with compatible illness, since only a small proportion of patients diagnosed with these diseases recall being bitten by a tick. The following tickborne diseases are reportable in NYC:

Disease

Organism

Vector

Endemic US States

Ticks in NYC

Lyme disease

Borrelia burgdorferi

Ixodes scapularis

(blacklegged or deer tick)

Northeast, mid-Atlantic, and Upper Midwest esp. CT, DE, ME, MD, MA, NH, NJ, NY, PA, RI, VT, VA, WV & MN, WI

Blacklegged tick found in Staten Island and northern Bronx.

Babesiosis

Babesia microti

Northeast & MN, WI

Anaplasmosis

Anaplasma phagocytophilum

Northeast, esp. NY, CT, NJ, RI & MN, WI

Ehrlichiosis

Ehrlichia chaffeensis

Amblyomma americanum

(lone star tick)

Southeast and south-central

Lone star tick has become more common in Staten Island and limited areas of the Bronx

Rocky Mountain spotted fever

Rickettsia rickettsii

Dermacentor variabilis

(American dog tick)

Throughout US, esp. NC, OK, AR, TN, MO

Dog tick found in all 5 boroughs

Powassan disease

Powassan or deer tick virus

Ixodes cookei (groundhog tick) or Ixodes scapularis

Cases reported from CT, MN, WI, NY, ME, MA, NH, NJ, PA, NC, RI, & VA, 2004-2016

Groundhog tick not identified in NYC; blacklegged tick see above

NYC Tickborne Disease Epidemiology

Tickborne diseases in NYC have been trending upward since 2000, with fluctuations from year to year. In 2017, the number of anaplasmosis and babesiosis cases approximately doubled in all boroughs except Queens, compared to 2016. There was a slight increase in Lyme disease cases in Brooklyn, Manhattan, and Queens. (Figure and Tables 1-5). Incidence rates of tickborne diseases are typically significantly higher in residents of Manhattan compared with other boroughs. However, since 2015, Staten Island has had the highest incidence rate of Lyme disease in NYC, which may be due to an increasing number of locally acquired cases. A subset of Lyme diseases cases, those with a physician reported erythema migrans (EM) lesion with onset between April 1 and October 31, are interviewed to assess travel. EM is a reliable indicator of recent infection and is used to identify locally acquired cases. Most interviewed cases with EM report a history of travel outside the City during the incubation period, most commonly to upstate New York, Long Island, Connecticut, Pennsylvania, New Jersey, and Massachusetts. Approximately half of interviewed Lyme disease patients with EM in Staten Island reported no history of travel during the incubation period (Table 4a). Local transmission of babesiosis was also reported in the Bronx and Staten Island and there was one report each of locally acquired anaplasmosis and ehrlichiosis in Staten Island residents. Blacklegged ticks collected in the Bronx and Staten Island have tested positive for Borrelia burgdorferi and Babesia microti (see tick surveillance below). Locally acquired RMSF cases while rare, have been reported in the past from all five boroughs.

Tickborne diseases may also be transmitted via blood transfusion. In 2017, there was one transfusion-associated babesiosis case and the first anaplasmosis case acquired from a blood transfusion in NYC. The incubation period for transfusion-associated babesiosis is two to nine weeks. Consider babesiosis in the differential diagnosis for patients with febrile illnesses and/or hemolytic anemia who have received blood components or transplanted organs in the preceding three months. Because these patients often have co-morbidities, and the potential exists for infection with other pathogens, consideration of babesiosis as a possible etiology may be delayed.

NYC Tick Surveillance Data

Information on tick populations in NYC is limited. Tick surveillance is conducted by the Health Department in select parks. In 2018, monthly tick surveillance will occur in 17 parks in NYC. Another 15 sites will be surveyed during high tick activity season from May to July.

 Ixodes scapularis (blacklegged tick or deer tick) has become widely established in Staten Island, and focal areas of the Bronx including Pelham Bay Park and Hunter Island. It is not established in other areas of NYC.

  • In 2016, ticks collected from parks in the Bronx (47%) and Staten Island (19%) tested positive for Borrelia burgdorferi. While 2017 tick testing results are not yet available, the density of blacklegged ticks doubled from 2016 to 2017 in areas of Staten Island (0.86 to 1.57 ticks/100m2) and the Bronx (4.13 to 9.37 ticks/100m2).
  • A much smaller number of ticks in the Bronx and Staten Island tested positive for Anaplasma phagocytophilum (0.06-10%), Babesia microti (0-6%) and the emerging pathogen, Borrelia miyamotoi (2%).
  • Significant numbers of I. scapularis ticks are found in counties and states surrounding NYC. Testing of ticks collected in the Hudson Valley by the New York State Department of Health (NYSDOH) found infection rates as high as 40-50% for Borrelia burgdorferi, 1-3% for Babesia microti and 7-15% for Anaplasma phagocytophilum.
  • One tick collected in the Bronx tested positive for Powassan virus in 2016, the first year Powassan viral testing was performed; however no human infections have been identified among NYC residents. In NY State, approximately 1 to 3 human cases are reported annually.

Dermacentor variabilis (American dog tick) has been detected in all boroughs of NYC.

Amblyomma americanum (lone star tick) has become widely established in Staten Island and in focal areas of the Bronx.

Clinical Guidelines
Detailed guidance on how to identify, diagnose and treat tickborne diseases can be found online in reference manuals for health care providers from the NYC Health Department, the Centers for Disease Control and Prevention (CDC), and the Infectious Diseases Society of America (IDSA) (see links below). Blood smear and polymerase chain reaction (PCR) should be used to diagnose babesiosis. Anaplasmosis and ehrlichiosis are best diagnosed using PCR during the first week of illness as antibodies may not be detectable for up to 10 days after illness onset. Paired serology demonstrating a four- fold change in IgG by immunofluorescence assay (IFA) can be used to diagnose anaplasmosis, ehrlichiosis, and RMSF. A clinical diagnosis of Lyme disease can be made in patients who present with an erythema migrans (EM) rash, which is often present before antibodies are detectable. Serologic testing for Lyme disease should adhere to the CDC recommended two-step process, in which an enzyme immunoassay (EIA) that is positive or equivocal is followed by a Western blot test (if Western blot is negative, no further testing is needed).
Tick Bite Management and Lyme Disease Prophylaxis

Attached ticks should be removed promptly with fine-tipped tweezers, ensuring that mouthparts have not been left in the skin. Guidelines developed by the IDSA support limited use of a single dose of doxycycline for adults and children  8 years old* as prophylaxis for Lyme disease when all of the following conditions are met:

  • Patient has traveled to a Lyme-endemic region
  • Tick has been attached for ≥36 hours, based on engorgement or history
  • Prophylaxis can be started within 72 hours of tick removal
  • Tick can be reliably identified as I. scapularis**
  • Patient does not have any contraindications to treatment with doxycycline
*Currently there is no guidance for excluded age groups.
**Doctors in endemic areas often learn to recognize deer ticks. For visual reference providers can refer to the DOHMH website.
Resources on the DOHMH and other websites

DOHMH – http://www1.nyc.gov/site/doh/health/health-topics/zoonotic-and-vectorborne-diseases.page http://www1.nyc.gov/site/doh/health/health-topics/ticks.page

Includes links to:

  •  Tickborne Diseases in the NYC Area: A Physician’s Reference Manual, 3rd edition. Call 311 to order copies. 
  • All About Ticks: A Workbook for Kids and Their Parents (English and Spanish). Call 311 to order copies.
  •  Information on ticks, tick bite prevention and repellents

CDChttp://www.cdc.gov/ticks/index.html

Includes links to:

  • CDC Tickborne Diseases of the United States: A Reference Manual for Health Care Providers, 4th edition (2017)  Webinars on novel and emerging tickborne diseases
  •  CDC videos on Medscape

IDSA Clinical Practice Guidelineshttps://academic.oup.com/cid/article/43/9/1089/422463
TICK ENCOUNTER RESOURCE CENTER OF THE UNIVERSITY OF RHODE ISLAND http://www.tickencounter.org/ NYS DOHhttps://www.health.ny.gov/diseases/communicable/lyme/

  •  Tick removal video
Reporting Cases

Clinicians and laboratories must report all cases of Lyme disease, babesiosis, RMSF, ehrlichiosis, anaplasmosis, and Powassan disease to the NYC Health Department. Cases of transfusion-associated tickborne diseases must also be reported to the NYSDOH Blood and Tissue Resources Program at 518-485-5341 and your hospital’s transfusion service.

Report cases to DOHMH by logging into Reporting Central via NYCMED, or complete the Universal Reporting Form:  http://www1.nyc.gov/assets/doh/downloads/pdf/hcp/urf-0803.pdf and mail or fax to 347-396-2632, or call the Provider Access Line at 1-866-692-3641. If a provider does not already have a NYCMED account, register at the NYCMED link above. Once logged in, Reporting Central can be found in the ‘My Applications’ section. See the Reporting Central New User Guide (PDF):  http://www1.nyc.gov/assets/doh/downloads/pdf/hcp/reporting-central-new-user-guide.pdf

 

FIGURE. Tickborne Diseases in New York City Residents by Year of Diagnosis  (See link for table)

 

TABLES 1-5. Number of NYC Confirmed and Probable Tickborne Disease Cases by Borough and Year 1. Anaplasmosis (See link for table)

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**Comment**

While alerting clinicians to the importance of considering TBD (tick borne diseases) is a good thing, only giving info from the CDC/IDSA is a huge mistake.  There is a Lyme war going on with two polarized sides believing different things.  To only put one viewpoint is extremely biased and unscientific.

The same old garbage is repeated here and the same old rotten tests.  The only people helped by this advisory are the ones lucky enough to test positive on a test that misses at least half of the cases.

As they say, “Garbage in, garbage out.”

For the ILADS guidelines, please see:  http://ilads.org/lyme/treatment-guideline.php  If you suspect TBD, please contact your local Lyme support groups as well as ILADS.  The IDSA and CDC will only prolong your suffering.

Heart Problems & Tick Borne Disease

Recently some articles have come out on Heart issues with Tick Borne Disease (TBD).  Most talk about Lyme; however, as you will see – there are many other players.

http://davidjernigan.blogspot.com/2015/05/functional-heart-problems-and-lyme.html  The Hansa Center in their blog states that a common symptom of chronic Lyme is Postural Orthostatic Tachycardia Syndrome or POTS.  POTS can cause headaches, lightheadedness, heart palpitations, fatigue, shaking, fainting, cold or pain in extremities, chest pain, shortness of breath, and even nausea.  Evidently, POTS can be caused by Lyme Endocarditis.

For an excellent read on Lyme Carditis, please see:  https://www.bayarealyme.org/blog/lyme-carditis-why-early-diagnosis-is-critical/  In a nutshell, it’s inflammation caused by an infection such as Lyme, viruses, and other pathogens.  This inflammation messes up electrical signal conduction and can cause AV block, a serious oxygen depriving condition, hence all the symptoms listed above.  Lyme Carditis is the more general term but it can be in any part of the heart: myocardium, pericardium, endocardium, cardiac muscle, valves, and aorta.  The good news is it can usually be reversed with appropriate treatment.  Sometimes a pacemaker is also needed.  The article states about 4-10% of people with TBD develop this.

CDC Expert Commentary by Joseph D Forrester, MD, MSc

Forrester states Lyme Carditis is “rare,” but even 4-10% of patients is a chunk of people.  PEOPLE HAVE DIED FROM THIS and even the CDC reported 3 cases of sudden cardiac death between Nov 2012 & July 2013 among patients with unrecognized Lyme carditis.  If one person died from Zika there would be a media blitz.  

https://www.ctvnews.ca/health/rare-but-serious-complication-of-lyme-disease-can-attack-the-heart-doctor-1.3952476  Recently a heart specialist in Ontario is warning doctors to be on the look out for Lyme carditis.  Dr. Baranchuk points out that numerous people with heart symptoms were admitted to the ER two to three times before anyone considered Lyme carditis.  He also states many don’t get the bullseye rash or notice vague symptoms of fever and muscle aches.

https://www.ctvnews.ca/mobile/video?clipId=1406334  CTV News Video

Baranchuk wrote a paper http://www.cmaj.ca/content/190/20/E622 advising doctors to treat young patients with strange heart problems with antibiotics while waiting for results of Lyme blood tests.

He states: “These patients may not require pacemakers to be implanted. They can be treated with IV antibiotics for 10 to 12 days and the electricity of the heart will recover completely forever,” he said.

Interestingly the title of the article by CTV News states, “Rare but serious complication of LD….” and yet they even quote Baranchuk saying,

“We have the suspicion that there are way more cases than are reported, because doctors are failing to report it,” he said.

That’s kind of a big deal.

QUIT SAYING THE WORD RARE IN YOUR REPORTING ON TBD.

Then there’s the story of Dr. Neil Spector, an oncologist who rubbed shoulders with experts and the best that medical care can offer and yet, due to doctors with heads in the sand suffered for years with bizarre and frustrating heart symptoms until he nearly crossed over to the other side. (He was told it couldn’t be Lyme as he lived in Florida.  The doctors were happy to diagnose him over the phone but ALL stated unequivocally he did NOT have Lyme!) After a heart transplant, Spector is speaking out about Lyme Disease and has even written the book, Gone in a heartbeat – A Physician’s Search for True Healing.  For a great review of the book:  https://www.lymedisease.org/when-lyme-disease-affects-the-heart/

Lyme and carditis:

https://madisonarealymesupportgroup.com/2017/06/10/lyme-carditis-with-complete-heart-block/

https://madisonarealymesupportgroup.com/2017/06/07/early-onset-lyme-carditis-concurrent-disseminated-erythema-migrans/

https://madisonarealymesupportgroup.com/2018/02/22/new-lyme-cme-course-available-lyme-carditis-more-than-blocked-beats/  Course for doctors to become educated.

But Lyme (Bb) isn’t the only culprit.

Similar to inflammation caused by Borrelia burgdorferi (Bb), inflammation can be caused by many bacteria and viruses:  https://www.myocarditisfoundation.org/research-and-grants/faqs/causes-of-myocarditis/

Most common viruses causing carditis:

  • Parvovirus B19
  • Human Herpes Virus 6
  • Enterovirus (Coxsackie Virus)
  • (Research needed.  Tons of viruses involved with TBD)

Most common bacteria causing carditis:

  • Corynebacterium diptheriae
  • Staphylococcus aureus
  • (Research needed.  Tons of bacteria involved with TBD)

Most common parasites causing carditis:

  • Borrelia burgdorferi
  • Ehrlichia species
  • Babesia species
  • Trypanosoma cruzi (Chagas Disease)
  • Bartonella (My addition due to the following…..)
  • (Research needed.  Tons of parasites involved with TBD)

I added Bartonella to the list due to the following (add it up, it isn’t rare):

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010976/  Five cases of infective endocarditis associated with Bartonella henselae.

https://www.ncbi.nlm.nih.gov/pubmed/9196420  Two cases of Bartonella Carditis.

https://www.ncbi.nlm.nih.gov/pubmed/11496560 One case.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5942242/ Four cases.

https://www.ncbi.nlm.nih.gov/pubmed/8849149 22 cases – 13 that had undetermined Bartonella species.

https://www.ncbi.nlm.nih.gov/pubmed/16762254  A total of 6 cases reported in Spain.  Conclusion states it is likely to be underestimated and to suspect it with negative blood cultures, history of chronic alcoholism, the homeless, and those in contact with cats or bitten by fleas or lice, as well as patients with endocarditis and positive serology against Chlamydia spp.  This abstract, written in 2006 wouldn’t have considered that ticks carry a Chlamydia-like organisms (CLO):  https://madisonarealymesupportgroup.com/2016/10/07/chlamydia-like-organisms-found-in-ticks/  These results suggest that CLO DNA is present in human skin; ticks carry CLOs and could potentially transmit CLOs to humans.  Two other studies have come to the same conclusion: that there exists a high prevalence and diversity of Chlamydiales DNA in ticks and the very real possibility of human infection. https://www.ncbi.nlm.nih.gov/pubmed/24698831 and https://www.ncbi.nlm.nih.gov/pubmed/26386066
All of this continues to demonstrate why Lyme Disease isn’t typically just Lyme Disease but MSIDS, multi systemic infectious disease syndrome, a literal menagerie of pathogens invading the human host making our cases extremely complex and difficult.

Bartonella and carditis:

https://madisonarealymesupportgroup.com/2017/01/04/endocarditis-consider-bartonella/

https://madisonarealymesupportgroup.com/2017/05/11/bartonella-henselae-in-children-with-congenital-heart-disease/

https://madisonarealymesupportgroup.com/2018/02/07/finally-rt-pcr-detected-bartonella-henselae-dna-on-tissue-valve/

https://madisonarealymesupportgroup.com/2017/05/20/bartonella-endocarditis-opportunistic-infection-in-cancer-patients-and-eye-inflammation/

Babesia and carditis:

https://madisonarealymesupportgroup.com/2018/02/20/babesia-and-heart-issues/

Mycoplasma, Chlamydia, Bb and carditis:

https://madisonarealymesupportgroup.com/2018/04/04/correlation-of-natural-autoantibodies-heart-disease-related-antibacterial-antibodies-in-pericardial-fluid-mycoplasma-bb-chlamydia/  Mycoplasma pneumoniae antibody positive patients had significantly higher anti-CS IgM levels. In CABG patients we found a correlation between anti-CS IgG levels and Mycoplasma pneumoniae, Chlamydia pneumoniae and Borrelia burgdorferi antibody titers. Our results provide the first evidence that natural autoantibodies are present in the PF and they show significant correlation with certain antibacterial antibody titers in a disease specific manner.

Hopefully by now it’s clear that carditis caused by TBD’s is not even close to rare.  It should also be painfully clear that we are truly in the dark ages on this and that much work needs to be done – and quickly.

Ending on a personal note, I had these bizarre heart symptoms early in my journey.  To say they were frightening would be an understatement.  I would wake in the middle of the night with my heart flopping like a fish out of water.  It felt like an elephant was sitting on my chest and my biceps were often numb.  I gasped for air as well.

Upon my first dose of Mepron, Artemisinin, and an intracellular antibiotic, I felt as if I was having a heart attack.  Thankfully we pulsed the artemisinin as that allowed the frightening herxes to dissipate some.  Due to my response to these drugs my guess is Babesia was the culprit.  https://madisonarealymesupportgroup.com/2016/01/16/babesia-treatment/  We treated Babesia for an entire year as it’s a notoriously persistent pathogen.  It’s important to hit it hard and long as it’s been known to build resistance to drugs.

There has been debate among some as to the effectiveness of Artemisinin and I do feel quality matters.  I’m a huge fan of this kind:  https://www.allergyresearchgroup.com/quality-artemisinin.  And no, I’m not affiliated with them in any way.  BTW:  We used 500mg morning and night MWF.  It makes your mouth taste metallic.

Do not mess around with heart symptoms.  Be a clanging gong until someone takes you seriously and feel free to copy this article and take it to your doctors.  They need to be educated and We the People are up to bat.

Lastly, please remember all the testing for ALL TBD is horrible.  You need a doctor who will diagnose and treat you clinically.  Your reaction to the medication is important to track as it will alert your doctor to what you are dealing with based on symptoms:  https://madisonarealymesupportgroup.com/2015/08/15/herxheimer-die-off-reaction-explained/

https://madisonarealymesupportgroup.com/2017/06/28/jarisch-herxheimer-a-review/

https://madisonarealymesupportgroup.com/2017/11/03/first-report-of-bartonella-quintana-immune-reconstitution-inflammatory-syndrome-complicated-by-jarisch-herxheimer-reaction/

Let’s suffice it to say, heart problems with tick borne illness is NOT rare.

 

 

Update on TBD’s in Travelers

https://www.ncbi.nlm.nih.gov/m/pubmed/29789953/

Update on Tick-Borne Bacterial Diseases in Travelers.

Review article

Eldin C, et al. Curr Infect Dis Rep. 2018.

Abstract

PURPOSE OF REVIEW: Ticks are the second most important vectors of infectious diseases after mosquitoes worldwide. The growth of international tourism including in rural and remote places increasingly exposes travelers to tick bite. Our aim was to review the main tick-borne infectious diseases reported in travelers in the past 5 years.

RECENT FINDINGS: In recent years, tick-borne bacterial diseases have emerged in travelers including spotted fever group (SFG) rickettsioses, borrelioses, and diseases caused by bacteria of the Anaplasmataceae family. African tick-bite fever, due to Rickettsia africae, is the most frequent agent reported in travelers returned from Sub-Saharan areas. Other SFG agents are increasingly reported in travelers, and clinicians should be aware of them. Lyme disease can be misdiagnosed in Southern countries. Organisms causing tick-borne relapsing fever are neglected pathogens worldwide, and reports in travelers have allowed the description of new species. Infections due to Anaplasmataceae bacteria are more rarely described in travelers, but a new species of Neoehrlichia has recently been detected in a traveler. The treatment of these infections relies on doxycycline, and travelers should be informed before the trip about prevention measures against tick bites.

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**Comment**

This review clearly shows how much work still needs to be done.  To boil down this complex illness to a round of doxycycline shows a simplistic understanding of these pathogens on steroids.  Mainstream researchers still haven’t gotten the memo that Eva Sapi reported about doxy throwing the spirochete into the non-cell wall form or the information that both pathologist Alan McDonald and microbiologist Tom Greer are finding spirochetes hiding in worms in the brains of folks with dementia and Alzheimer’s.

To announce doxy as the “one side fits all” treatment is truly uninformed.

While doxy is a great front-line drug, patients need to be monitored closely for symptoms.  Since testing is so poor, doctors should also be educated on:  https://madisonarealymesupportgroup.com/2017/09/05/empirical-validation-of-the-horowitz-questionnaire-for-suspected-lyme-disease/  Print out and complete the symptom check lists and take them with you to your appointment.

Remember, Lyme is the rock star we all know by name.  There are many wanna-be’s just as powerful often at play:  https://madisonarealymesupportgroup.com/2017/07/01/one-tick-bite-could-put-you-at-risk-for-at-least-6-different-diseases/  The number is actually 18 and counting.

Please encourage doctors to become educated.  It’s our only hope.

https://madisonarealymesupportgroup.com/2018/02/19/calling-all-doctors-please-become-educated-regarding-tick-borne-illness-heres-how/

Here is an example of good Lyme treatment:  https://madisonarealymesupportgroup.com/2016/02/13/lyme-disease-treatment/

Type other pathogens into the search bar to get other treatment suggestions.  Feel free to copy these off and share with your practitioner.