Benefits of berberine against chronic disease


By Rhonda Patrick


Berberine is an alkaloid compound present in the roots, stems, rhizomes, and bark of a variety of plants, including Californian poppy, goldenseal, cork tree, Chinese goldthread, Oregon grape, and several plants in the Berberis genus. It is also widely available as a dietary supplement. Berberine has a long history of use in the ancient and traditional medicine systems of India, China, and Persia. Animal and limited human studies demonstrate that berberine may exert pharmacological effects against certain chronic health conditions such as cardiovascular disease, gastrointestinal disorders, neurodegenerative disease, depression, and metabolic dysfunction. Preliminary research in animals also suggests that berberine may exert anti-aging properties and might be beneficial in combating aging-related diseases. However, the bulk of research involving berberine has been conducted in animals, with a paucity of trials in humans. (See link for article)



Berberine has been a God-send for us.  It has been shown to:

  1. lower lipids
  2. have antioxidant properties
  3. have anti-inflammatory properties
  4. reduce blood glucose levels
  5. protect the liver (in cell-culture studies)
  6. help neurodegenerative disorders
  7. have anti-depressant effects (in mice)
  8. have anti aging effects (in cells, insects, and rodents)
  9. thwarts negative effects of some pharmaceutical drugs
  10. have action against Bartonella:

For more:

Interestingly, Japanese Barberry, a source of Berberine, is a hot-spot for ticks.

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