The weekend is a practical demonstration teaching hyperbaric ozone and 10 pass. For local injections, there will be a demo epidural, superior hip approaches, prostate, female (if available) and all local joints. You will be introduced to kinesiology, a must to locate dental disturbances which might foul results.
For John Trowbridge’s remarks on the workshop:
All trainees get to be listed on Dr. Rowan’s website, a site that gets a lot of traffic of patients looking for ozone therapy. Many attendees state that they get an average of one patient a week from the listing.
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**Comment**
I post this information as I feel ozone to be a great tool in a practitioner’s tool-box. As with all other modalities, I do not believe it to be curative. Despite what practitioners state, a “tune-up” with ozone is continued treatment, therefore, not curative. There are numerous techniques including blood ozone, where ozone is put directly into the blood, as well as by injection and in combination with prolotherapy for pain. Some drink ozonated water, and there are ozone saunas. You can also use ozone rectally and vaginally and in the ear. There is also topical ozone in ozonated olive oil. Go here for a video about how I used it (warning: gross pictures): https://madisonarealymesupportgroup.com/2018/03/02/dmso-msm-for-lyme-msids/
BTW: I own an ozone machine and have used it rectally/vaginally daily – sometimes numerous times a day. I never herxed and I never noticed a change.
My biologic dentist uses ozone in all her surgeries and my husband has had the prolozone for pain due to Lyme disease with very good results. We have both utilized single-pass blood ozone under UV light weekly for 2.5 months. Again, we never herxed or had noticeable improvement. I do believe ozone is dose dependent and we probably needed it stronger.
Dr. Rowan teaches these techniques in his workshops as well as 10-pass and EBOO (dialysis-type blood ozone which is a continuous circuit). Many patients have felt relief nearly instantly, and it works against viruses as well as bacteria. The EBOO type is particularly strong but costs $900-$1,000 for ONE treatment, and you need to go to the doctor’s office to have it done, so you can see the impracticality of it for many patients as a singular treatment for Lyme/MSIDS. It may be something you save up for and do a stint of with the goal of hitting any potential viruses and cleaning up the blood as well as getting more oxygen into the body which has a lot of health benefits.
My friend and I are walking to dinner when it hits. My jaw clenches, my hands curl into fists, and it feels like my head will explode. My mind fills with overwhelming rage over absolutely nothing and everything remotely annoying that’s ever happened to me. I try to distract myself by listening to my friend, but I can’t hear her over the cacophony of my racing thoughts. Intrusive violent fantasies take over. I resist the urge to stomp my feet and scream. There’s not much that I can do at this point. I just tell myself it’ll pass… and a few minutes later, it does.
Rage is one of many mental health issues people with Lyme Disease face. A study in Neuropsychiatric Disease and Treatment found that 68 percent of Lyme patients experienced explosive anger, homicidal thoughts, and/or suicidal thoughts.Other studieshave found that 54 percent of Lyme patients suffer from irritability or mood swings, 23 percent have anxiety, 21 percent experience depression, and 13 percent meet the criteria for obsessive compulsive disorder.
I’m one of those people. And I am far from alone.
Christina Giaquinto experienced extensive anxiety after being diagnosed with Lyme disease. Credit: Christina Giaquinto
The Mental Cracks Of Lyme Disease
Kerri Lynn Neugebauer, a 47-year-old marketing and talent director in Pittsburgh, experienced intense paranoia while she was suffering from Lyme. “I thought I was being followed when I was out,” she remembers. “I would wake up in the middle of the night clawing at the walls because I thought I was trapped. And every time we came home from being out, I thought someone was in the house.”
For Kirsten Stein, a 49-year-old Bay Area Lyme Foundation board member in California, the primary mental health symptom was anxiety. “I have been flying in planes since I was 12 years old, yet while experiencing symptoms immediately prior to being diagnosed, I had a panic attack on airplane out of the blue,” she says.
“I would wake up in the middle of the night clawing at the walls because I thought I was trapped. “
“As someone who has experienced anxiety in the past, I can always tell the difference when it is ‘Lyme anxiety,’” says Christina Giaquinto, a 28-year-old life coach in New Jersey. “When someone experiences [non-Lyme] anxiety, it is because they are thinking of something that causes a physical reaction. With Lyme, it is the complete opposite. It attacks without cause. You feel very trapped because there is nothing you can do to fix it since there is no cause.”
Giaquinto also experienced depression and derealization from Lyme.
“I constantly felt like I was in a video game watching everyone else live,” she says. “It took away my sense of self.”
Why Lyme Causes Mental Health Problems
Understanding of the mechanisms by which Lyme causes these problems is still in its infancy, but what do know that the bacteria that cause Lyme can get into the central nervous system, and inflammation in the brain and throughout the body can lead to mental health symptoms, says psychiatric physician Rupali Chadha, MD.
Because Lyme infects the white blood cells of the immune system, it can also throw off your gut and brain microbiome, which can in turn lead to imbalances of neurotransmitters and hormones, says Bill Rawls, MD, an integrative health expert on Lyme and other chronic illnesses. “While we don’t have definitive data on a cause or prevalence, we do see patients with Lyme disease in psychiatrists offices,” says Chadha.
“Feeling like your brain is on fire is bad enough, but not being understood by the medical profession or by the people around you makes everything 10 times worse,” says Rawls.
Mental illness associated with Lyme can come not just from the Lyme itself but also from certain treatments, as well as from knowing you have a chronic and difficult-to-treat illness. Mike Robinson, a 53-year-old cannabis researcher in Santa Barbara, developed depression and anxiety as a result of receiving a Lyme diagnosis and says it worsened after antibiotic treatment. He also chalks his mental health struggles up to “the way it makes your body feel, the neuropathic pain it causes, and the stigma about it.”
People with neurological Lyme disease often test negative for Lyme, says Wendy Adams, Research Grant Director at the Bay Area Lyme Foundation. This means that instead of receiving Lyme treatment, they’re frequently given labels such as OCD or schizophrenia without receiving help for the underlying issue.
Mike Robinson, a 53-year-old cannabis researcher in Santa Barbara, developed depression and anxiety as a result of receiving a Lyme diagnosis.
What To Do When Lyme Affects Your Mental Health
If you’re struggling with mental health symptoms that may be due to Lyme, Chadha recommends seeing a physician rather than just a therapist about it, since treatment will require you to get to the physical root of the issue. “Therapy may be very useful and may be recommended and added,” she says. “But if someone has Lyme disease and develops psychiatric symptoms, they need to see if physician to see if they require biological treatment i.e. medication.”
Rawls usually recommends antimicrobial herbs to patients dealing with mental illness and other neurological symptoms of Lyme, since antibiotics aren’t always able to kill Lyme in the central nervous system and herbs can also help restore immune function. The herbs he uses to heal the nervous system include berberine, andrographis, cat’s claw, Japanese knotweed, garlic, and sarsaparilla. “Healthful diet, clean environment, low stress, and an active lifestyle are all essential for overcoming chronic Lyme disease,” he says.
Even if Lyme sometimes takes over my mind, it doesn’t have to take over my life.
In the meantime, be as patient with yourself as you can. Due to the myth that mental illness is within your control, it can be tempting to blame yourself, especially with symptoms like rage that people have trouble sympathizing with. If Lyme causes you to engage in behavior you wouldn’t otherwise, Rawls suggests forgiving yourself, as you’re dealing with an illness, and focusing on doing better next time. Reducing your stress and gaining as much control over your life as you can will help, he says.
Though my journey with Lyme isn’t over yet, my rage has gotten easier to deal with because I’ve learned a new approach to it. Instead of just getting more mad about the fact that I’m mad, I validate how I’m feeling and try to do something nice for myself, like getting something to eat or drink or lying down and resting. I remind myself that it’ll pass, and if it comes again, it will pass again after that. Even if Lyme sometimes takes over my mind, it doesn’t have to take over my life.
__________________
**Comment**
Please keep in mind that although Dr. Rawls is a doctor, he’s now in the business of selling herbs.
We performed a retrospective study to determine the time frame for symptom resolution in 78 pediatric patients hospitalized with laboratory-confirmed early-disseminated or late-stage Lyme disease. The vast majority of the patients improved promptly after receiving appropriate antibiotics. Patients with a longer duration of arthritis before the institution of therapy experienced a longer time to recovery.
Prospective:A prospective study watches for outcomes, such as the development of a disease, during the study period and relates this to other factors such as suspected risk or protection factor(s). The study usually involves taking a cohort of subjects and watching them over a long period.
Retrospective:A retrospective study looks backwards and examines exposures to suspected risk or protection factors in relation to an outcome that is established at the start of the study. Most sources of error due to confounding and bias are more common in retrospective studies than in prospective studies. You should take special care to avoid sources of bias and confounding in retrospective studies.
In this retrospective study, there is going to be bias as they again use “laboratory-confirmed” testing, which is going to be that same-o-same-o CDC two-tiered serology that misses over half of all cases. A chunk of patients are omitted right from the get go.
The only redeeming statement is that those with longer duration of arthritis before treatment required a longer recovery. Unfortunately, due to bias, so many patients are omitted, so many symptoms were not accepted, and therefore this study only regurgitates previous studies done by The Cabal:https://madisonarealymesupportgroup.com/2017/01/13/lyme-science-owned-by-good-ol-boys/
Many scientists have been ostracized for not following the party line.
In February, an exciting threshold in medical history was crossed: a team of scientists at the University of Pittsburgh used contemporary gene editing tools to alter a bacteriophage. The phage — a tiny organism that preys on bacteria — was then used to treat a young English woman, Isabelle Holdaway, who was suffering from a previously untreatable bacterial infection.
One of the scientists to identify this moment as historic was Steffanie Strathdee, an infectious disease epidemiologist at the University of California San Diego (where she heads up a phage research and treatment program called IPATH) and the author of The Perfect Predator: A Scientist’s Race to Save Her Husband from A Deadly Superbug (Hachette Books, 352 pp.).
That titular race played a key role in sparking the recent wave of renewed interest in phages. Strathdee’s experience was, as her book’s title suggests, horrific. Her husband contracted a superbug infection while travelling in Egypt and was saved by an eleventh-hour intravenous phage treatment. But — as she put it when we spoke to her about her book, phage technology, and the looming superbug crisis —
“it wasn’t really until my husband’s case hit the news” that phages caught the interest of the medical mainstream again. “He was treated with phage therapy in March of 2016. In April of 2017, the results were presented at the Pasteur Institute for the 100th anniversary of the discovery of bacteriophages.”
This wider medical recognition is long overdue, in Strathdee’s opinion. “Phages,” she told us, are “actually the oldest and most ubiquitous organisms around. It’s estimated that there are ten million, trillion, trillion phages on the planet. They’re in soil. They’re in water. They’re on our skin. They’re in our guts.” Despite this ubiquity, their potential use as an anti-bacterial agent was not discovered until 1917. A French biologist and entrepreneur, Felix d’Herelle, managed to isolate them and use them to treat dysentery. While d’Herelle’s discovery soon fell into the shadow of the discovery of penicillin, phages went on to enjoy a robust medical use in the Soviet Union and in some European nations. However, the medical uses of phage, Strathdee explained, were largely ignored in the U.S. and elsewhere — even as the tiny organisms proved to be foundational for much of modern microbiology.
“About half of the Nobel Laureates in the 1950’s and 60’s won because of their work on phages,” she points out. “But they were seeing phages as a tool. They were never really forgotten in basic biology, but they were forgotten in medicine. Even with CRISPR [a powerful contemporary gene-editing tool], phages were used as a tool to discover it. CRISPR is really a form of the bacteria’s immune system that they equipped themselves with to protect themselves from phages.”
These organisms have taken on new significance in what Strathdee frighteningly called our “post-antibiotic” age. She describes her husband as its “poster child,” a sobriquet she bestowed because the bacteria infecting him had “acquired a resistance gene to Colistin — the last resort antibiotic — right around the time a paper was first published in Lancet reporting the appearance of this gene in pigs in China. By the time people looked to see if it was other places, it was already in 30 countries. It was mindblowing, to be honest. We’re at a time now where simple scrapes and surgeries are leading to infections that are increasingly untreatable. It’s not universal, but we’re seeing more and more people coming in to hospitals for a knee replacement, or a pacemaker replacement, or appendicitis, or bariatric surgery. And they’re acquiring superbugs. I know because they’re calling us at IPATH. They’re calling every day.”
How did we get here?
“We were complacent as a society,” Strathdee says. “New antibiotics were being developed. We thought that we could stay ahead of the bacteria. We were shocked to realize that they were way ahead of us. But this is not only due to our overuse in people, it’s due to our overuse in livestock and agriculture. Seventy-five percent of all antibiotics used in the U.S. are actually used in livestock to make pigs and cows and chickens grow fatter faster. In hospitals poor infection control can lead to the spread of antimicrobial resistance as well. About 15 percent of inpatients in hospitals in the U.S. these days acquire a superbug while they’re there — often MRSA or C. diff. Worse still, many of these superbugs are not reportable at the national level in the U.S. My husband’s infection was reportable in Germany at the national level. But it wasn’t reportable in California. We’re not monitoring antimicrobial resistance very well, either.”
She cites a frightening anecdote about the bacteria that almost killed her husband: she herself, when working towards her Ph.D. in the late 1980’s, used to plate it on Petri dishes with no fear. Since then, it has become a nearly unstoppable killer.
It’s important to put emphasis on that nearly. Strathdee titled her book The Perfect Predator to reflect her view of phages. They generally function in a simple but deadly way: by entering bacterial cells and using their internal biological machinery to reproduce more and more phages.
“When given the kill signal,” she told us, “these baby phages burst out of the bacterial cell and then they, in turn, go to attack more bacteria until there’s none left.” This is what makes them so potentially powerful as treatments: they are the last organisms left capable of taking on bacteria adapted to the flood of antibiotics inundating the modern world. And not only can they work as a form of direct therapy. They have powerful applicability as a secondary treatment as well. As Strathdee points out, they can sometimes make antibiotics efficacious again against superbugs previously resistant to them: “The bacteria are faced with a genetic decision when they’re being attacked by those phages and antibiotics at the same time. They need to evade both attackers at the same time, and in some cases they modify themselves so that they’re susceptible to the antibiotics again.”
When it comes to longer-term risks associated with phage therapy, Strathdee is blunt.
“We haven’t seen any so far. And we’ve been injecting phages into people.” She also points out that because each phage is specialized to attack only certain bacteria, when they have done their work they are excreted “almost magically by the body, without hurting any of the other friendly bacteria.”
There is, however, a short-term hurdle.
Phages, while in many cases ruthless killing machines, can sometimes be “temperate,” to use the current term of art. This means that instead of hijacking the bacterium and changing it into a phage-production facility, they instead enter the bacterial cell and become dormant. Strathdee calls this “hitting the snooze button.” These phages “integrate their genetic material into the genetic material of the bacterial cell. And with it they can integrate other parts of their DNA — toxin genes or even antibiotic resistance genes. Often they have a defense mechanism whereby they make the bacterial cell impervious to new attacks from other phages. So they are not only not killing the bacterial cell in this situation, but actually causing potential harm.”
This is why the phage developed by the Pittsburgh team had to be gene-edited in order to be effective: Isabelle Holdaway was infected with Mycobacterium asepsis, a member of the same genus of bacteria as those that cause tuberculosis. The phages that attack mycobacterium belong to the “temperate” category, and they required the deletion and addition of genes in order to realize their potential as perfect predators. There is an element of poetry in all this, grim as it is: consider Strathdee’s observation that CRISPR itself comes from phage work against bacteria and is now being used to edit phages to make them still more effective in the fight.
And effective they are. They saved Tom Patterson’s life, and appear to be saving Isabelle Holdaway’s. The young woman is, Strathdee notes, still under treatment — her infection is a difficult one to get rid of, even with phage therapy. But, says Strathdee,
“Isabelle was in hospice and now she’s emailing me, texting me, sending me pictures of her cat, and asking when we’re coming to visit so that she can make cupcakes. She’s learning how to drive, she’s taking her A-level exams. She’s just a happy teenager.”
Nonetheless, work remains to be done.
“We need to know a lot more about phage biology,” Strathdee says, before the question of temperate phages can be conquered fully. “The lab scientist who did the genetic modification of the phage to treat Isabelle says, basically, ‘Let’s not run before we walk. Let’s do carefully controlled studies, rigorous controlled clinical trials, and do them right. And publish and work together as a field, globally, because this is a global health problem.’” This work is all the more necessary because, as Strathdee pointed out, a number of major pharmaceutical companies are making strategic exits from the antibiotic development market. “New antibiotics take 10 to 15 years to develop, and at least a billion dollars. And most pharmas are getting out of the industry because they’re too expensive and because they’re being told the shelf life of these antibiotics is short. We need a new incentives model for antibiotics.”
But that alone, in Strathdee’s opinion, won’t be nearly enough. Phages are important precisely because they offer a powerful complement or even an alternative to existing anti-biotic therapies.
“It’s generally believed now,” she says, “that phage therapy is probably the best alternative to antibiotics that we have. And this isn’t just a problem in the U.S. or the U.K. It’s a problem everywhere. By 2050 one person every three seconds is going to be dying from a superbug infection, unless something drastic turns this around.”
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**Comment**
I’ve been told phage therapy wouldn’t work with Lyme/MSIDS due to the lack of host specificity. In other words, the phage must directly line up with the specific bacteria in order to work. Also, most of us are dealing with more than one bacteria, and battle worms, parasites, and other lovely beasts thrown into the mix to keep us humble.
The take home from this abstract is that the bacteria we are infected with are intelligent and stealthy, changing within us to further their goals. They don’t want to kill us, just maim and weaken us so they can live long, full lives. Also, notice “slow-growing bacteria,” which should serve as a clue to practitioners that these types of organisms scoff at 21 days of antibiotics.
Lyme disease often misdiagnosed, resulting in unnecessary antibiotics
JUL 15, 2019 —
Please see the letter below to the TBDWG announcing yet another propaganda paper published by Paul Auwaerter
——— Original Message ———-
From: CARL TUTTLE <runagain@comcast.net>
To: tickbornedisease@hhs.gov, chris.smith@mail.house.gov
Cc: (98 Undisclosed recipients)
Date: July 14, 2019 at 8:50 AM
Subject: Lyme disease often misdiagnosed, resulting in unnecessary antibiotics
To: the Tick-Borne Disease Working Group,
Please see the letter below addressed to Dr. Paul Auwaerter who “speaks with great authority” in his recent interview with Healio.
-Carl Tuttle
Letter to Auwaerter:
——- Original Message ———-
From: CARL TUTTLE <runagain@comcast.net>
To: Paul Auwaerter <pauwaert@jhmi.edu>
Cc: psax@bwh.harvard.edu, jli@bwh.harvard.edu, cbusky@idsociety.org, tkobaya5@jhmi.edu, jmstiglich@healio.com, infectiousdisease@healio.com
Date: July 14, 2019 at 8:33 AM
Subject: Lyme disease often misdiagnosed, resulting in unnecessary antibiotics
Lyme disease often misdiagnosed, resulting in unnecessary antibiotics
Kobayashi T, et. Open Forum Infect Dis. 2019;doi:10.1093/ofid/ofz299.
“Many patients seen for infectious disease evaluation of Lyme disease usually have multiple, longer standing complaints such as fatigue and musculoskeletal pain yet have been treated with antibiotics when there is not good evidence they have an active infection,”
Disclosures: Auwaerter reports serving on a scientific advisory board for DiaSorin.
July 14, 2019
The IDSA Foundation
1300 Wilson Boulevard Suite 300
Arlington, VA 22209
Attn: Paul Auwaerter, vice chair of the IDSA Foundation
Dear Dr. Auwaerter,
The Healio article doesn’t mention how the hard fact of “not infected” was established; do you have some revolutionary test we don’t know about yet?
I would like to call attention to the following publication coauthored by Dr. Paul Mead of the US Centers for Disease Control formally announcing that serology is wholly inadequate for the management of Lyme disease.
“These serologic tests cannot distinguish active infection, past infection, or reinfection. Reliable direct-detection methods for active B. burgdorferi infection have been lacking in the past but are needed and appear achievable.”
From the Tick-Borne Disease Working Group 2018 Report to Congress: (Page 40)
“Metagenomic sequencing of DNA/RNA and proteomics can be used to identify tick-borne pathogens in clinical samples.”
Dr. Auwaerter… I would like to suggest that part of the grant money in the “search for infectious cause of Alzheimer’s disease” be directed toward organizing a nationwide proficiency test program to find out if there are any methods already available to detect Borrelia burgdorferi, Borrelia miyamotoi, Borrelia mayonii, Borrelia lonestari, Borrelia hermsii, and Borrelia turicatae (known pathogens in the U.S.) in simulated blood or plasma samples.
I believe that Milford Molecular Diagnostics may have this capability right now so doesn’t it make sense to focus on direct detection methods as soon as possible or are we going to promote outdated serology from DiaSorin for the next decade?
A response to this inquiry is requested.
Sincerely,
Carl Tuttle
Lyme Endemic Hudson, NH
Cc: Paul E. Sax, MD, EDITOR-IN-CHIEF, Open Forum Infectious Diseases
Of note, Auwaerter is on the scientific advisory committee of Diasorin, a company that makes diagnostic tests for Lyme as well as EBVhttps://www.diasorin.com/en/node/8937.
In 1970 DiaSorin began the development of Infectious Disease products designed for use with ELISA technology. Since 2001 it has launched a broad array of new CLIA products, with unique infectious disease assays for use on the LIAISON® systems.
All DiaSorin Infectious Disease products are registered in compliance with the European CE mark rules with commercially available assays in the US having FDA clearance.
Madison Area Lyme Support Group 