Archive for the ‘Pain Management’ Category

How DMSO Treats ‘Incurable’ Autoimmune and Contractile Disorders

https://www.midwesterndoctor.com/p/how-dmso-treats-incurable-autoimmune?

How DMSO Treats “Incurable” Autoimmune and Contractile Disorders

The decades of research that could have prevented an immense amount of human suffering

A Midwestern Doctor

Oct 20, 2024

Story at a Glance:

•DMSO is a remarkably safe substance that effectively treats a variety of conditions (e.g., chronic pain, acute injuries, and strokes) that medicine has struggled with for decades. Many readers here have already experienced profound benefits from using it.

•DMSO is a powerful (but safe) anti-inflammatory agent that is often extremely helpful for autoimmune conditions. For example, it’s frequently used to treat asthma, inflammatory bowel diseases (e.g., ulcerative colitis and irritable bowel syndrome), interstitial cystitis (painful bladder syndrome), ITP, lupus, multiple sclerosis, myasthenia gravis, scleroderma, Sjogren’s syndrome, and uveitis.

•DMSO is also remarkably effective at stabilizing and refolding proteins. This allows it to treat a variety of “untreatable” genetic disorders, and conditions characterized by the abnormal accumulation of misfolded proteins in the body (e.g., amyloidosis) or chronic deposits of excessive contractile collagen (e.g., surgical scars, abdominal adhesions, Dupuytren’s contractures, and Peyronie’s disease). Two of the most dramatic examples of this are scleroderma and fibrodysplasia ossificans progressiva—both “untreatable” conditions where DMSO can provide truly lifesaving benefits.

•In this article, I will present the wealth of evidence substantiating each of those uses, share my theory on how the unusual antimicrobial properties of DMSO explain some of these benefits, and present DMSO treatment protocols for many of those disorders. Additionally, since many readers requested it, I put together a simplified guide on how to use DMSO orally or topically.

Dimethyl sulfoxide (DMSO) is a simple and readily available naturally occurring chemical that rapidly enters the body through the skin and has a variety of remarkable therapeutic properties. When it was discovered, its proponents believed it (much like antibiotics) represented a new therapeutic principle in medicine and once adopted, would completely change how medicine was practiced. Unfortunately, the FDA conducted a reprehensible campaign against it and was able to successfully bury it.

Since there are so many uses for DMSO, to effectively present them, I’ve had to comb through well over ten thousand pages of scientific literature and then order them into a logical sequence (of what will be roughly a nine-part series). For instance, in the first part of this series, I discussed how DMSO completely changed the management of neurological injuries and showed that were it to be adopted, millions would no longer be disabled from the common emergencies we view as insurmountable within the current medical paradigm (e.g., frequent disabilities from stroke and the inevitability of becoming a paraplegic after a spinal cord injury).  (See link for article)

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**Comment**

DMSO has been a well-kept secret among those who are desperate enough to learn about it.  If you are new to it, go here for a basic article and helpful videos that explain it in layman’s terms as well as MSM, a derivative of DMSO.  I also include helpful info on dosages, etc.

I’ve used it many times over the years and always with good, measurable results.

I highly recommend reading a Midwestern Doctor’s thorough article in full as the good doctor goes through many conditions DMSO treats as well as the scientific studies and experiences behind them.

He goes through DMSO use for MS, Lupus, Asthma, Interstitial cystitis, Uveitis, inflammatory bowel diseases, Myasthenia gravis, Sjogren’s syndrome, as well as the possible bacterial component (even the challenges of pleomorphism) in many of these conditions and how DMSO is bacteriostatic, antiviral and antifungal.

You can use DMSO topically (recommended for newbies first), orally, intramuscularly, and intravenously.

Its only downsides are the tingling, itching in topical applications as well as the odor for all applications.  The severity of smell is commiserate with the amount used.

Go here for more:

[DMSO’s] virtues were extolled in another Congressional Hearing, this one taking place on March 24, 1980, before Claude Pepper’s Select House Committee on Aging. The drug was DMSO, and the opponent, as in Senator Johnson’s Hearing, was once again the FDA.

As with Ivermectin, the FDA [Bureau of Drugs] Director, Dr. J. Richard Crout, explained—tongue in cheek—that the agency would be the first to advocate DMSO’s use if it had only evidence that it worked.

“The FDA is willing, indeed anxious, to approve DMSO for such uses whenever controlled trials meeting the statutory standard are available [Page 61].

In place of Dr. Pierre Kory sat Dr. Stanley Jacob, a professor of surgery at the University of Oregon Medical School. Dr. Jacob was the dynamic Harvard-trained physician who headed the University of Oregon Transplant Program and had discovered many of the benefits of DMSO after first using it as a cryoprotectant.

Dr. Jacob testified before the committee in 1980, just as Dr. Kory would do some 40 years later, in 2020, and told an unbelievable story to a group of Washington D.C. insiders about the miraculous benefits of an almost unknown drug.

Like Dr. Kory, he has been proven correct.

Dr. Kory authored a book about his experience entitled The War Against Ivermectin: The Medicine that Saved Millions and Could Have Ended the Pandemic.

Dr. Jacob authored the book Dimethyl Sulfoxide (DMSO) in Trauma and Disease.

DMSO met the same fate in 1980 as Ivermectin did following Dr. Kory’s Congressional hearing in 2020: The FDA buried it.

The FDA shut down research on DMSO in 1965 after an estimated 100,000 patients began enjoying its benefits.

Many states have laws that steer licensed physicians away from prescribing DMSO for anything other than interstitial cystitis.

Sound familiar?

Category:

Activism, Pain Management, research, Treatment

DMSO: Its History and Remarkable Properties

https://www.midwesterndoctor.com/p/the-remarkable-history-and-safety?

The Remarkable History and Safety of DMSO

Please share your experiences with DMSO with the readers here!

A Midwestern Doctor
Oct 12, 2024

Note: this article has two primary purposes. First, it is a compilation of all the existing safety and toxicology data on DMSO for anyone planning to utilize it in a clinical setting. Second, it is meant to serve as a place to collect reader’s (often incredible) experiences with DMSO so individuals who are considering using DMSO can have testimonials to juxtapose with the wealth of data I am gradually presenting on DMSO.

My time in the medical field has led me to accept many medical practices are adopted because of politics or economics rather than because existing evidence shows they work. Nonetheless, certain instances of this happening still astound me to this day, particularly the blacklisting of DMSO (dimethyl sulfoxide) as:

  • This simple chemical is incredibly safe and effective and treats a wide range of challenging medical conditions that impact millions that still lack an effective therapy (outside of DMSO).
  • Because of its efficacy, once discovered, it took the country by storm, resulting in millions using it, the scientific community getting behind it and publishing thousands of studies on DMSO, numerous pharmaceutical companies making large investments to bring it market, professional athletes promoting it, numerous governors, congressional representatives and senators (on behalf of both themselves and their constituents) pressuring the FDA to give it a fair chance for decades and state legislatures independently legalizing it because the federal government would not.
  • Many approved pharmaceutical products take advantage of DMSO’s properties to work (e.g., in those products, DMSO is often classified as an inert “vehicle”). Similarly, DMSO is FDA approved for one condition (interstitial cystitis) and is approved for a wide variety of veterinary uses (e.g., the same conditions it treats in humans).
  • Over the past 40 years, more than 10,000 articles on the biological implications and 30,000 articles on the chemistry of DMSO have appeared in the scientific literature—much of which, as I’ve shown here is remarkably compelling and paradigm shifting in healthcare.
  • Yet, despite all of that, DMSO was effectively erased from history. It is now widely seen as an unproven and dangerous therapy, and even within the natural health field, most people do not know it exists.  (See link for article)

https://www.midwesterndoctor.com/p/dmso-could-save-millions-from-brain?

DMSO Could Save Millions From Brain and Spinal Injury

The decades of evidence showing DMSO revolutionizes the care of many “untreatable” circulatory and neurologic conditions.

Sep 15, 2024
By a Midwestern Doctor

Story at a Glance:

  • DMSO is a remarkably safe chemical that protects cells from otherwise fatal stressors (e.g., freezing, burning, shockwaves, ischemia). Since the heart, brain, and spinal cord are particularly vulnerable to injury, DMSO can produce miraculous results for those conditions.
  • The usage of DMSO completely transforms the management of strokes (including brain bleeds), heart attacks, and spinal cord injuries. As I will show here, had the FDA not sabotaged DMSO’s adoption, in addition to countless lives being saved, millions could have been protected from a lifetime of disability or paralysis.
  • DMSO has many other remarkable properties. For example, it stabilizes proteins, and thus treats many challenging protein disorders (e.g., amyloidosis and numerous genetic disorders).
  • Many conditions DMSO treats are typically considered to be incurable. In this article, I will focus on DMSO’s remarkable utility for the conditions that respond best to intravenous DMSO (e.g., a variety of circulatory disorders like varicose veins or Raynaud’s) and complex neurological disorders (e.g., Down’s Syndrome, Developmental Delay, ALS, Alzheimer’s, Parkinson’s), along with how to administer IV DMSO and DMSO stroke protocols.

If I were stranded on a desert island or knew the world was ending and I could only bring a few therapies with me, one of them, without a doubt, would be DMSO. This is because:

  • It treats a wide range of severe illnesses which are often otherwise incurable and frequently fatal or lead to a lifetime of permanent disability.
  • It effectively treats acute injuries and rehabilitates chronic musculoskeletal disorders (e.g., arthritis). Because of this, it’s one of the best “pain medicines” out there and has allowed many to get their lives back.
  • It has a variety of unique properties that open up a completely different dimension to how medicine can be practiced.
  • It is one of the safest medically active substances in existence.

Remarkably, in the 1960s, this was recognized and DMSO took the nation by storm (e.g., people everywhere were clamoring for it, gas stations would often advertise they sold it, and tens of thousands of research studies were conducted by enthusiastic scientists around the globe). Now however, outside of it being a laboratory chemical or an alternative therapy some people use for joint pain, few are even aware of DMSO’s existence.

This was due to the FDA waging a multi-decade long war against DMSO (despite widespread outcry from Congress and the public), which I believe was arguably the worst thing the FDA has ever done to the country.

Since I am uniquely positioned to present many of the forgotten sides of medicine to the public, I’ve long felt the DMSO story needs to be told. Simultaneously however, since there is a wealth of data on this topic, I wanted to ensure I honored the importance of this subject and accurately present it. For this reason, I’ve spent the last three months reading and arranging thousands of pages of literature. Since there is so much to say on this topic, this series will be broken into a few parts. In the first installment, I will cover the key properties of DMSO and the challenging conditions where it provides the most profound benefits. (See link for article & note there will be another part to it explaining where to get it, dosing, and non-IV protocols)

https://www.midwesterndoctor.com/p/dmso-is-a-miraculous-therapy-for

DMSO is a Miraculous Therapy for Chronic Pain and Musculoskeletal Injuries

The decades of evidence DMSO revolutionizes the practice of medicine

A Midwestern Doctor
Sep 29, 2024

Story at a Glance:

•The standard approach for treating pain and musculoskeletal injuries typically involves giving NSAIDs (e.g., ibuprofen), and in more severe cases, opioids. Unfortunately, these drugs are extremely dangerous (e.g., each one kills tens of thousands of people each year), but nonetheless have remained the standard of care for decades.

•DMSO is a remarkably effective pain-killing agent, in many cases allowing individuals who’d been disabled for years by their pain (e.g., a failed spine surgery or severe arthritis—DMSO’s most popular use) to get their lives back. Furthermore, it can treat many types of pain other therapies do not work on (e.g., complex regional pain syndrome).

•DMSO is a highly effective therapy for healing wounds and creating healthy scars, making it particularly helpful for recovering from surgery.

•DMSO is incredibly effective for healing a wide range of acute and chronic musculoskeletal injuries (e.g., arthritis, headaches, neck and back strains, restless leg syndrome, sprained ankles, trigeminal neuralgia and numerous traumatic injuries). It typically has an 80-90% success rate and often has an instant and dramatic effect. This use was particularly popular with professional athletes, as it allowed many of them to quickly return to the field rather than be out for the rest of the season.

•In this article, I will review the scientific literature that explains how DMSO provides pain relief and healing, the vast body of evidence (comprising of thousands of patients) showing it indeed does, and our preferred DMSO home treatment protocols for pain, arthritis, and musculoskeletal injury (along with the best sources for procuring DMSO).  (See link for article)

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https://www.midwesterndoctor.com/p/how-dmso-treats-incurable-autoimmune

How DMSO Treats “Incurable” Autoimmune and Contractile Disorders

The decades of research that could have prevented an immense amount of human suffering

A Midwestern Doctor
Oct 20, 2024
Article excerpts:

DMSO is a powerful (but safe) anti-inflammatory agent that is often extremely helpful for autoimmune conditions. For example, it’s frequently used to treat asthma, inflammatory bowel diseases (e.g., ulcerative colitis and irritable bowel syndrome), interstitial cystitis (painful bladder syndrome), ITP, lupus, multiple sclerosis, myasthenia gravis, scleroderma, Sjogren’s syndrome, and uveitis.

  • DMSO is also remarkably effective at stabilizing and refolding proteins. This allows it to treat a variety of “untreatable” genetic disorders, and conditions characterized by the abnormal accumulation of misfolded proteins in the body (e.g., amyloidosis) or chronic deposits of excessive contractile collagen (e.g., surgical scars, abdominal adhesions, Dupuytren’s contractures, and Peyronie’s disease). Two of the most dramatic examples of this are scleroderma and fibrodysplasia ossificans progressiva—both “untreatable” conditions where DMSO can provide truly lifesaving benefits.
  • In this article, I will present the wealth of evidence substantiating each of those uses, share my theory on how the unusual antimicrobial properties of DMSO explain some of these benefits, and present DMSO treatment protocols for many of those disorders. Additionally, since many readers requested it, I put together a simplified guide on how to use DMSO orally or topically.

One of DMSO’s remarkable properties is its ability to function as a chemical chaperone and stabilize the three dimensional structure proteins assemble (fold) themselves into. This is important as many complex illnesses (e.g., many genetic disorders) result from misfolded proteins and presently can only be (ineffectively) managed with expensive drugs that aim to normalize the function of the abnormal proteins.

In turn, a few drugs have been developed to refold misfolded proteins, and to my knowledge, the most helpful ones on the market were the ones developed to treat cystic fibrosis (after the Cystic Fibrosis Foundation gave 150 million to bring these medications to market which currently are priced at roughly 300,000.00 a year). However, unlike the existing pharmaceutical chaperones (which are very specific to the misfolded protein), DMSO’s effect is remarkably universal.

Studies have shown DMSO can improve the functionality of the dysfunctional proteins that are seen in genetic disorders like cystic fibrosis,1 hereditary nephrogenic diabetes insipidus,1,2 Machado-Joseph disease,1 Niemann–Pick disease,1,2,3,4,5,6 and a defective protein that causes motor disorders and early death in mice.1 Likewise, it can also treat a variety of complex diseases which result from misfolded proteins damaging surrounding tissue.  (See link for article.  He gives a study in which DMSO was used to treat Alzheimer’s, contractures, Peyronie’s disease, FOP, Scleroderma, & other autoimmune issues like lupus, asthma, IT, MS IBD, MG,& Sjogren’s syndrome) .  Also many patient testimonials are given, including the improvement of Downs Syndrome.)

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**Comment**

Some of the most thorough articles on DMSO yet.  I highly recommend making a pdf of them for your own usage.  This safe treatment has been attacked by the FDA so it may be nearly impossible to get good information on it in the future.

For more:

Category:

Alzheimer's, Pain Management, research, Treatment

Ross Lyme & Tick-borne Diseases Protocol Version 4

https://www.treatlyme.net/lyme-disease-treatment-guidelines

About The Ross Lyme & Tick-borne Diseases Protocol—Version 4

New in Version 4

The Ross Lyme & Tick-borne Diseases Protocol–Version 4 update, released 6/17/24, has a number of significant changes.

Name change. In Version 4, I have updated our name to include “tick-borne”. This recognizes that people can have Bartonella, Babesia, or other tick-borne diseases, separate from having Lyme (Borrelia) infection.

But there are more significant updates than our name change. Version 4

  • Emphasizes plant-based foods recommendations in Part 2. Diet;
  • Promotes healthy intestinal microbiome—even on antibiotics with a new Part 3. Healthy Intestinal Microbiome; and
  • Includes an herbal antibiotic only option to treat the three Bs (Borrelia, Bartonella, and Babesia) simultaneously in Part 12. Lyme Infection and Part 13. Bartonella & Babesia Infections.
  • Moves lifestyle, and related areas, of sleep, diet, healthy intestinal microbiome, and exercise to the front of the protocol to emphasize the key role these areas have in recovery.

Introduction

These are support and treatment guidelines to treat chronic Lyme or tick-borne infections. This protocol addresses most problems that keep a person from getting well. It is more comprehensive than the antibiotic focused Infectious Disease Society of America (IDSA), International Lyme and Associated Disease Society (ILADS), and United States Centers for Disease Control and Prevention guidelines. While herbal and prescription antibiotics may decrease the germ load in chronic Lyme and tick-borne infections, they often do not correct the underlying problems that cause ongoing symptoms.

The Ross Lyme Support Protocol includes essential steps for the beginning and throughout a chronic Lyme disease or tick-borne infection treatment. It is designed to:

  • boost the immune system,
  • improve detoxification,
  • speed recovery,
  • kill the infections, and
  • protect and repair from the harmful effects of the infections and the herbal or prescription antibiotics.

While the following Lyme disease and tick-borne infection treatment approach focuses on a limited number of areas, it may correct most of the problems like:

  • low energy,
  • pain,
  • insomnia,
  • brain, neurologic, and thinking problems (brain fog), and
  • immune compromise and suppression.

Herxheimer Reactions. When a person starts a Lyme disease or tick-borne infection treatment or changes herbal and prescription antibiotics, it is common to experience some worsening in symptoms. See Herxheimer Die-off Reaction: Inflammation Run Amok for more information about this and the steps you can take to treat it.

Treatment Length and Persistence. Generally, it takes a minimum of six months to see if these supports and treatments will help. Supplements can speed recovery, but treating Lyme still takes time. Once you have marked improvement, then you can likely stop many of these nutritional supports except for probiotics, curcumin, ashwagandha, and a good multivitamin. See Getting Healthy: Will I? When? How Do I? for more information about Lyme disease and tick-borne infection treatment length and persistence.

About Supplements. Throughout this protocol I include supplements as nutritional supports based on their known functions. Basic research and my clinical experience show they may help the various symptoms and problems in Lyme disease and tick-borne infections.  (See link for article)

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**Comment**

Lots of great info here.

For more:

Category:

Babesia, Bartonella, Detoxing, diet and nutrition, Lyme, Pain Management, Sleep, Supplements, Treatment

Wheelchair Bound CEO Walks After Lyme Disease Treatment

https://danielcameronmd.com/wheelchair-bound-ceo-regains-ability-to-walk-after-lyme-disease-treatment/

WHEELCHAIR-BOUND CEO REGAINS ABILITY TO WALK AFTER LYME DISEASE TREATMENT

walk-lyme-disease

Lyme arthritis is characterized by joint swelling lasting for weeks to months and potentially causing permanent joint damage. It can worsen symptoms in patients with existing joint conditions such as osteoarthritis and may go undiagnosed, leading to unnecessary surgeries.

By 

In this case report, “Exacerbation of Osteoarthritic Joint Pain by Lyme Disease,” Bennani and colleagues demonstrate the importance in identifying an underlying tick-borne infection, as appropriate treatment can dramatically improve a patient’s quality of life.¹

A 63-year-old man, who was wheelchair-bound, presented to his clinician’s office with severe pain in both knees, which had been progressively worsening over several months.  He had previously undergone bilateral knee arthroscopies for meniscal tears and recently received corticosteroid injections, which did not alleviate his pain.

The authors suggest that while corticosteroids can reduce inflammation and alleviate pain, the bacterial infection can continue to proliferate and destroy knee tissue.

“Before treatment, our patient was wheelchair-bound due to the combination of existing osteoarthritis and the manifestation of Lyme disease in his knees.”

“The patient did report that he was recently on erythromycin for an upper respiratory infection (URI) and indicated that his knees felt better while he was taking erythromycin,” the authors state.

Furthermore, the patient, who worked as a chief executive officer (CEO) of a company, was an avid hunter and reported that his dog had Lyme disease.

Given that the patient’s dog had Lyme disease, Lyme IgG and Lyme IgM studies were ordered.

Testing for Lyme disease was positive and the patient began treatment with doxycycline.

“Upon completion of doxycycline therapy, our patient noted significant improvement in his knee pain,” the authors state.

His improvement was so significant that the patient no longer needed the use of a wheelchair and was able to cancel his bilateral knee replacement surgery.

Authors conclude: 

  • “Our patient was able to avoid a costly, high-risk surgical procedure with the detection and treatment of his Lyme disease.”
  • “Lyme disease should always be a consideration in the differential diagnosis of patients who have lived or have traveled to areas that are endemic to the disease and who tend to have outdoor lifestyles.”
Related Articles:

Successful treatment for Lyme arthritis after knee surgery
Borrelia burgdorferi causes prosthetic joint infection
Lyme arthritis and periprosthetic joint infections

References:
  1. Bennani A Z, Chegwidden B, Lambroussis C G, et al. (April 29, 2024) Exacerbation of Osteoarthritic Joint Pain by Lyme Disease. Cureus 16(4): e59318. doi:10.7759/cureus.59318

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**Comment**

The first thing my mind said to this was duh!  Of course the man felt extremely better when being on erythromycin!  But, alas, this is where we are in 2024 – after 40 years of mythology about tick-borne illness.

Nothing’s changed.

If you want real help, you must go outside the mainstream medicine (MSM) paradigm, and get to a Lyme literate doctor (LLMD) even though MSM still calls them quacks.

A few important points:

  • He’s an avid hunter and is outside.  This raises the risk for tick-borne infections but you can still get infected in your own backyard.
  • His dog has Lyme.  This happened in our family as well.  Dogs are sentinels and a warning shot over the bow.  Testing for animals appears to be much better than for people and if your pet is infected – be on guard.  Estimates for Lyme based on canine models and human seroprevalence data is far higher than ‘official’ data.
  • While corticosteroids are loved by doctors for reducing inflammation and pain, they are a double-edged sword for patients who are infected.  Since they dampen the immune system they allow infections to worsen which is why identifying underlying infections is imperative.
  • I’m sorry but by NOW, if a patient improves while on antibiotics, the FIRST thing they should consider is tick-borne infections.  I mean really, this nonsense has gone on for far too long.
  • This man was lucky in that he tested positive.  What about the sorry suckers who don’t?  I’ll tell you what happens – they are kicked to the curb and allowed to languish for years and years and years until their lives are destroyed and it kills them.  Not a very happy ending but it’s happening to thousands upon thousands.
  • Notice the miraculous turn around of this patient.  This often happens – but sometimes it doesn’t because the WRONG treatment is used and it’s a different pathogen to blame.  There is nuance to treating this and MSM is woefully uneducated and unprepared.  Run away from MSM as fast as you can and get to someone who knows what they are doing.  I’m serious.  Don’t mess around with this.  You will thank me later.

For more:

Category:

Inflammation, Lyme, Pain Management, research, Testing

ACTION: Protect CBD

https://anh-usa.org/action-center/? Go here to contact your reps.

Take Action Now to Protect CBD!

The House Agriculture Committee is considering amendments to the upcoming Farm Bill. We need to act fast to oppose a terrible amendment that would federally ban all ingestible hemp products with any level of THC. 

This would destroy a huge percentage of the industry, including many CBD and full-spectrum hemp oil products that have many health-supporting cannabinoids along with naturally-occurring but non-intoxicating levels of THC.

You can read the text of the amendment here. 

We must oppose this amendment and preserve our access to CBD and full-spectrum hemp oil products. Write to your member of Congress to oppose this amendment!

For more:

CBD is what pharmacologists call a promiscuous drug. That means it could be effective for treating a number of medical conditions. In broad strokes, CBD affects more than one process in the body – a term called polypharmacology – and so could benefit more than one medical condition.

As of early 2023, there are 202 ongoing or completed scientific trials examining the effectiveness of CBD in humans on such diverse disorders as chronic pain, substance use disorders, anxiety and arthritis.

In particular, CBD appears to be an anti-inflammatory agent and analgesic, similar to the functions of aspirin. This means it might be helpful for treating people suffering with inflammatory pain, like arthritis, or headaches and body aches.

CBD also holds potential for use in cancer therapy, although it has not been approved by the FDA for this purpose.

And this, right here, is why it simply must go.  It does too many things simultaneously that interferes with Big Pharma profits and since most of our politicians are all in bed with Big Pharma, there is a concerted effort to ban it, plain and simple.

 

 

 

Category:

Activism, Cancer, Hemp Oil, Herbs, Inflammation, Pain Management, Supplements