Archive for the ‘Inflammation’ Category

Unraveling Bartonella: Dr. Mozayeni

https://www.betterhealthguy.com/episode185

Episode #185: Unraveling Bartonella with Dr. B. Robert Mozayeni, MD

 
 
About My Guest

My guest for this episode is Dr. B. Robert Mozayeni.  B. Robert Mozayeni, MD is an expert in Translational Medicine, the science and art of advancing medical science safely and efficiently.  He is the Chief Medical Officer of Galaxy Diagnostics, LLC.  He is a co-founder of the Foundation for the Study of Inflammatory Diseases.  He serves as an advisor to pharmaceutical and nutraceutical companies and serves on an Institutional Review Board specializing in nutraceutical products for pain management.  He is the immediate past President of ILADS, the International Lyme and Associated Diseases Society where his goal was to advance the science of translational medicine.  In late 2019, Dr. Mozayeni launched T Lab Inc., a research and clinical laboratory engaged in research using advanced microscopy to understand better the pathogenesis of disease in inflammatory conditions associated with persistent infections.  He has research and clinical expertise with regard to autoimmune diseases and the effects of chronic infection and inflammation on vascular physiology and neurovascular conditions seen commonly with autoimmune and neurovascular diseases.  With a strong foundation in the basic sciences and evidence-based medicine, he analyzes complex medical cases using a combination of basic scientific principles and clinical experience along with the balance of the evidence base.  Dr. Mozayeni has published numerous papers on immunology and cerebrovascular blood flow hemodynamics.  He has been actively researching and publishing his work on chronic rheumatic diseases and their relationship to persistent human Bartonella spp. infection.  Of note, chronic persistent Bartonella spp. infections are strongly associated with neurovascular diseases.  Thus, Dr. Mozayeni is uniquely qualified in the combined areas of chronic persistent endovascular infections and related rheumatological and neurovascular diseases.   He has also published papers providing new insights as to a potential infectious  (Bartonella spp.) cause of osteoarthritis and also, a case of arthritis associated with hypermobility that was likely caused by Bartonella spp.

Key Takeaways
  • What advances have been observed in recent years in the realm of Bartonella?
  • What are common symptoms of Bartonella?
  • How is Bartonella transmitted?- Might Bartonella lead to autoimmunity?
  • Can Bartonella be a trigger for PANS?
  • Might Bartonella be a contributor to osteoarthritis?
  • Is there a connection between Bartonella and hypermobility or EDS?
  • Does Bartonella contribute to MS?
  • What is the connection between Bartonella and SIBO?
  • Can Bartonella act as a trigger for MCAS?
  • Is Bartonella activation observed in those with COVID?
  • What is the state of the art in Bartonella testing?
  • What is Babesia odocoilei?
  • What agents are most helpful in the treatment of Bartonella?
  • Is there a place for herbs and other natural interventions in Bartonella treatment?
  • Should pets be considered as a potential source of exposure to Bartonella?
Connect With My Guest

http://TMGMD.com

Related Resources

Article: Unraveling the Mystery of Bartonellosis

Transcript

Go to top link for transcript, video, and audio

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Category:

Bartonella, Cancer, Eye Issues, Heart Issues, Inflammation, Psychological Aspects

9 Lyme & Tick-borne Disease Hacks & Dr. John Aucott’s Lyme Research Update

https://www.treatlyme.net/guide/lyme-tick-borne-disease-hacks  Video Here (Approx. 35 Min)

Nine Lyme and Tick-borne Disease Hacks

Marty Ross MD presents nine hacks for Lyme and tick borne disease. Watch this video and Powerpoint presentation to find real ways to improve your health.

This is a second recording of a video Powerpoint presentation first delivered to the Canadian Lyme Disease Research Network Virtual 2023 Awareness Event on May 23, 2023.

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Watch Dr. John Aucott’s update on latest Lyme disease research

Dr. John Aucott, Director of the Johns Hopkins Lyme Disease Research Center, recently delivered an overview of Lyme and other tick-borne disease research. You can watch a replay of his presentation below.

What follows is the introduction to Dr. Aucott by Shireen Rusby, one of the founders of Maryland’s Lyme Care Resource Center.

May is Lyme disease awareness month. Like any “awareness” effort, the intent is to increase the attention to and appreciation for the subject. In the case of Lyme disease there is a particularly powerful irony to the concept of awareness. Lyme disease is an illness that is often hidden and its symptoms unrecognized, yet the patient can be so overwhelmed that there is little reprieve from the self-awareness that dominates each day.

Those of us living with Lyme disease, as well as those living with many other long-term, hidden health conditions, have experienced very similar scenarios – the body’s natural inclination toward homeostasis is challenged.

Balance becomes harder to achieve and maintain. Lyme has imbalanced us, COVID has imbalanced us, ME/CFS has imbalanced us, dysautonomia and POTS have imbalanced us. So while our bodies, minds and spirits are making constant efforts to balance and rebalance physically, mentally and emotionally, what is the impact of stressors on a system that is already experiencing overload?

Well, that’s a whole thesis in and of itself and we’re not going to cover it tonight. But there is one stressor that we can increase “awareness” of this evening. For members of the Lyme community and those of other hidden illnesses, the challenges of dysfunctional homeostasis are compounded by the emotional strain of invalidation.

What interferes with healing

When we then begin to doubt our own reality, we make efforts to normalize the abnormal state of our being and that in turn leads to an even greater maladaptive response and further interferes with healing.

In his book, Conquering Lyme Disease, Dr. Brian Fallon states: “The experience of being disbelieved and misrepresented over and over is inherently traumatizing. Some patients…have identified this atmosphere of disbelief (and the resulting social isolation and self-doubt) as the single most stressful aspect of their illness experience.”

Some of you may have seen the movie Avatar. It is a futuristic story of human beings landing on another planet and attempting to conquer the native people of that land. When greeting each other, these natives to whom we are supposedly superior, look each other in the eye and say, “I see you.”

This simple phrase encapsulates much of our ongoing struggle in the medical world. It speaks to a fundamentally necessary component of the practitioner-patient relationship that is at times absent in this journey with invisible illness.

Many medical professionals may not know where to turn when blood work looks normal and verifiable analytical tools fail to provide objective evidence. The simple truth, however, is that an absence of evidence is not evidence of absence. That quote, often attributed to the astrophysicist Carl Sagan, can serve as an incredibly powerful guiding principle when it comes to illnesses like Lyme disease.

The art of inquiry

Our lack of comprehensive and neatly packaged scientific proof need not preclude our awareness and acknowledgement of the situation. Rather, this is an opportunity for us to practice the art of inquiry as the necessary first step on the path of healing.

And certainly, there is no one path of healing in illnesses as complex as Lyme disease, and that adds to the challenge for both the patient and the practitioner. The fractured Western paradigm of medicine, in its tendency to compartmentalize and classify health as black or white, present or absent, positive or negative often fails to recognize the holistic nature of human suffering.

But the path of healing is first paved with recognition of and respect for the imbalanced body, mind and spirit.

Our journey to regain and retain balance begins again each day. In paving this path let us remember to turn toward the light especially when it seems dark, and let us use the tools of compassion and understanding to help one another.

Fostering awareness of this hidden yet ever-growing health pandemic will increase the opportunities for healing, and will turn the tide against the history of glaring invisibility and deafening silence.

We have as our guest speaker tonight someone who has made it his mission to foster the awareness of Lyme disease. He has paved the path of healing for countless Lyme warriors with sound practices and with stellar science.

John Aucott and his amazing team at the Lyme Disease Research Center, have partnered with many, first and foremost with the patients they serve, to produce the scientific evidence necessary to authenticate many of our struggles – struggles which we have experienced for months, years or even decades, while seeking out the rare practitioner like him who looks at us and says “I see you.”

For your endless support, for your validation of what we endure, and for your ongoing efforts to find the evidence that may have once seemed absent –we offer our endless gratitude.

http://  Approx. 2 hours

LCRC May 2023: Advances in Lyme Disease and Tickborne Disease Research

Dr. Aucott will be discussing research advances in Lyme Disease and Tickborne Diseases, including an update on diagnostics, potential biomarkers, advanced neuroimaging, and future treatments.

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Category:

Activism, Detoxing, diet and nutrition, Gut Health, Herbs, Inflammation, Lyme, Mold, Supplements, Testing, Treatment

New Lyme Study Being Used to Support CDC Narrative: You Aren’t Infected, You Just Have A Simple Immune Response

https://www.nbcnews.com/health/health-news/lyme-disease-symptoms-recover-fast-others-not-rcna83340  Video Here (Approx. 4 Min)

By Caroline Hopkins

Why some people recover from Lyme disease, while others experience months, years or even decades of chronic symptoms has long puzzled doctors. New research offers some clues to an immune system marker in the blood that is elevated among people with lingering Lyme disease symptoms, even after they’d received antibiotics.

In the new study, published on May 9 in the Center for Disease Control and Prevention’s Emerging Infectious Diseases journal, researchers found an immune system marker in the blood called interferon-alpha was elevated among people who had been treated for Lyme disease but had lingering symptoms.

Interferon-alpha is one of a handful of key signaling proteins the body makes to tell immune cells to fight off bacteria or viruses. If the blood levels are too high, the immune system can overact, causing pain, swelling and fatigue — symptoms often seen with Lyme disease.

In patients with high levels of interferon-alpha, the immune response to the Lyme bacteria may cause chronic inflammation, even once the infection is gone, said Klemen Strle, an assistant research professor of molecular biology and microbiology at Tufts University and an author of the new study.

“We think this is a possible driver of persistent symptoms,” Strle said. And since a number of drugs are already approved to lower interferon-alpha, he suggested the research could mean a possible treatment option for lingering Lyme symptoms.

The study was small, including 79 people diagnosed with Lyme disease, and found only a link between the higher interferon-alpha levels and the persistent Lyme disease symptoms, not that the immune marker was itself causing the lasting symptoms. A larger clinical trial would be needed to affirm the connection.

Male and female adult blacklegged ticks, Ixodes scapularis, on a sesame seed bun to demonstrate relative size.
Male and female adult black-legged ticks, Ixodes scapularis, on a sesame seed bun to show their relative size.CDC

Anywhere from 30,000 up to 500,000 people develop Lyme disease from a tick bite each year, according to the CDC. For most, the infection is mild and easily treated with antibiotics. About 10% experience symptoms like fatigue and brain fog along with muscle, joint and nerve pain that persists even after treatment.

The new findings represent a significant shift in understanding why some people infected with Lyme suffer chronic symptoms. Previously, some researchers believed that a specific strain of the spiral-shaped Borrelia burgdorferi bacteria that causes Lyme might be a cause. Others wondered whether undetectable low levels of infection lingered in the body after treatment. The new research suggests that the way the body reacts to the bacteria — not the bug itself — could result in long-lasting symptoms.

It’s still unclear why some people have elevated interferon-alpha, but Strle said he’s looking into a possible genetic cause.  (See link for article)

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To reiterate:

  • This study consisted of 79 people diagnosed with Lyme based off of matched serum and CSF samples.  Once again, no seronegative patients are represented.
  • A link between higher interferon-alpha levels and the persistent Lyme disease symptoms was found.  This does not prove causality.
  • This DOES NOT present a “significant shift in understanding.” It just supports the accepted, politicized CDC narrative that persistent/chronic infection doesn’t exist despite global research and reality which says it does.
  • Far more than 10% experience these depilating chronic symptoms.  They continue to regurgitate this number which only includes those diagnosed and treated early.  It doesn’t include the far larger subset of patients that are diagnosed and treated late.

Go here to read Lyme advocate Carl Tuttle’s letter to Strle where he reminds him that while interferon alpha has also been found in patients with chronic hepatitis, it wasn’t blamed for chronic hepatitis but rather was correlated with the presence of viral replication, or persistent viral infection.  He then reminds Strle of a 1995 case study on a Lyme patient who received multiple courses of IV and oral meds yet relapsed after each one and that the only way this patient stayed in remission was when kept on open ended clarithromycin.  To cinch the deal, Tuttle reminds Strle of a 2018 study of 12 Canadian Lyme patients who were culture positive for infection even after multiple years on antibiotics.  Tuttle simply but wisely asks the obvious question: would a chronic, persistent Lyme infection raise IFN-a levels?

‘The powers that be’ are desperate to continue the narrative because there’s a big Lyme “vaccine” in the pipeline that could make them lots of money.  A chronic/persistent infection would not be conducive to a vaccine.

Category:

Inflammation, Lyme, research

Best Supplements For Arthritis

https://www.paintreatmentdirectory.com/posts/the-best-supplements-for-arthritis

The Best Supplements for Arthritis

The Best Supplements for Arthritis

By: Cindy Perlin, LCSW

3/26/23

There is no one treatment that will address all the complex factors that affect the onset and progression of osteoarthritis (OA) and rheumatoid arthritis (RA). Certain supplements can be very helpful for reducing arthritis pain and improving function . Some of the most powerful are turmeric, fish oil, ginger, SAM-e, chondroitin sulfate, glucosamine and CBD.These supplements have anti-inflammatory and/or joint rebuilding effects.

The best results will be obtained by combining supplements with an anti-inflammatory diet, exercise and stress management. There are also therapies that can be very effective, for the treatment of arthritis, including acupuncture, massage, physical therapy, low level laser therapy and pulsed electromagnetic therapy (PEMF).

Anti-inflammatory drugs can have serious, even fatal, side effects, including causing potentially fatal GI bleeding and increasing the risk of heart attacks and strokes and reducing immune response. Using safer, natural supplements to reduce inflammation and pain is a better strategy.

Although OA was once considered primarily a degenerative and non-inflammatory condition, it is now recognized as having inflammatory aspects, including elevated cytokine levels, as well as potentially being connected with systemic inflammation.

Turmeric 

Turmeric (active ingredient curcumin) reduces pain, inflammation and stiffness related to rheumatoid arthritis and osteoarthritis (OA).  This herb is traditionally used in Chinese and Indian Ayurvedic medicine to treat arthritis. It also blocks inflammatory cytokines and enzymes, including cyclooxygenase-2 (COX-2), the target of the anti-inflammatory prescription drug celecoxib (Celebrex).

In a small 2012 pilot study, curcumin reduced joint pain and swelling in patients with active RA better than diclofenac (Voltaren), a nonsteroidal anti-inflammatory drug (NSAID). Unlike NSAIDs, curcumin was not found to be associated with any adverse events.[3]

A 2016 systematic review and meta-analysis provided scientific evidence that 8–12 weeks of standardized turmeric extracts (typically 1000 mg/day of curcumin) treatment can reduce arthritis symptoms (mainly pain and inflammation-related symptoms) and result in similar improvements of the symptoms as ibuprofen and diclofenac sodium without the gastrointestinal and cardiac risks of NSAIDs

A 2018 study lasting 12 weeks found that both turmeric and turmeric combined with boswellic acid improved function and reduced joint pain, though the combination worked better to improve performance than curcumin alone.

So turmeric could be part of the answer to the question, “What is the best supplement for arthritis?”

Arthritis Foundation recommended dosage: Capsules, extract (more likely to be free of contaminants) or spice. For OA: Capsule, typically 400 mg to 600 mg, three times per day; or 0.5 g to 1 g of powdered root up to 3 g per day. For RA: 500 mg twice daily. Curcumin is a key chemical in turmeric

Shop for Products with Turmeric 

Fish Oil (Omega-3 fatty acids)

Fish oil reduces inflammation and morning stiffness in rheumatoid arthritis and preliminary studies indicate it may have a similar effect on osteoarthritis. Fish oil is an excellent source of omega-3 fatty acids (including EPA and DHA), which block inflammatory cytokines and prostaglandins. The body converts them into powerful anti-inflammatory chemicals called resolvins. Resolvins are molecules that promote resolution of cellular inflammation, allowing inflamed tissues to return to a healthier state.EPA and DHA have been extensively studied for RA as well as many other inflammatory conditions.

A 2010 meta-analysis found that fish oil significantly decreased joint tenderness and stiffness in RA patients and reduced or eliminated NSAID use.

A 2005 study of people with RA showed enhanced positive effects when fish oil supplements were used in combination with olive oil.

A 2018 review of the evidence of the benefits of fish oil for RA found that consumption of Omega 3 fatty acids significantly improved eight disease-activity-related markers.

Fish oil is also important for brain, eye and heart health. It also helps with anxiety and depression. It is safe, with no significant adverse effects. So it just may be another answer to “What is the best supplement for arthritis?”

Arthritis Foundation recommended dosage: Fish, capsules, softgels, chewable tablets or liquid. For general health, two 3-ounce servings of fish a week are recommended. However, it’s difficult to get a therapeutic dose of fish oil from food alone. To treat arthritis-related conditions, use fish oil capsules with at least 30 percent EPA/ DHA, the active ingredients. For RA and OA, up to 2.6 g, twice a day

Ginger

Ginger decreases joint pain and reduces inflammation both in people with osteoarthritis (OA) and rheumatoid arthritis (RA) Ginger has been shown to have anti-inflammatory properties similar to ibuprofen and COX-2 inhibitors such as celecoxib (Celebrex). Ginger also suppresses inflammatory molecule called leukotrienes and switches off certain inflammatory genes, potentially making it more effective than conventional pain relievers. Side effects are limited to mild gastrointestinal upset in some patients.

A 2010 study of 247 patients with knee OA found that ginger reduced knee pain when standing and walking and improved quality of life.

In a 2012 in vitro study, a ginger extract called Eurovita Extract 77 reduced inflammatory reactions in RA synovial cells as effectively as steroids.

For OA, In one trial of more than 200 patients, Eurovita Extract 77 improved OA pain after standing and walking.

A 2015 study found that using ginger extract nanoparticals in a cream 3x a day for 12 weeks improved knee joint pain, daily activities, sports activities and quality of life. There were no adverse effects.

A 2017 study of twice a week self-knee massage with ginger oil in patients with OA found patients had reduced pain and improved function after one and five weeks.

A 2019 study found that ginger can alter gene expression in people with RA to improve disease manifestation.

Arthritis Foundation recommended dosage: Powder, extract, tincture, capsules and oils, up to 2 g in three divided doses per day or up to 4 cups of tea daily. In studies, 255 mg of Eurovita Extract 77 (equivalent to 3,000 mg dried ginger) twice daily.

SAM-e

S-adenosyl-methionine (SAM-e) is a compound found naturally in the body that has anti-inflammatory, cartilage-protecting and pain-relieving effects. In studies, supplementing with SAM-e was as effective at relieving OA pain as NSAIDs like ibuprofen and celecoxib, without their side effects. A systematic review published in 2011 of complementary and alternative medicines in the management of osteoarthritis found consistent evidence that SAM-e was effective in the management of osteoarthritis. No adverse effects were found in any of the studies.

SAM-e also has a mild to moderate antidepressant effect, and is frequently used as a natural alternative to anti-depressant medication..

The typical SAM-e dose is 1,200 mg daily. It will take a few weeks to see the effects..

Glucosamine

Glucosamine is a major component of joint cartilage and levels drop as people age. It also helps keep the cartilage in joints healthy and may have an anti-inflammatory effect. Glucosamine produced in the body provides natural building blocks for growth, repair and maintenance of cartilage and may lubricate joints, helping cartilage retain water and prevent its breakdown.  It is often combined with chondroitin (see below).

Supplements are derived from the shells of shellfish (such as shrimp, lobster and crab) or from animal bones or fungi.

The largest study to date, the 2006 Glucosamine/chondroitin Arthritis Intervention Trial (GAIT) looked at 1,600 people with knee OA. The first phase found that patients with moderate-to-severe arthritis experienced significant pain relief from combined glucosamine and chondroitin. The 2008 phase found that glucosamine and chondroitin, together or alone, did not slow joint damage. In the two-year-long 2010 phase, glucosamine and chondroitin were found as effective for knee OA as celecoxib (Celebrex).

Other research has suggested that glucosamine does slow joint damage. A 2008 retrospective study of nearly 275 patients found those using glucosamine for at least 12 months underwent half as many joint replacement surgeries as those on placebo.

In a small 2012 study, an improvement in symptoms after 12 weeks was seen with combined glucosamine and NSAIDs, and a smaller but still significant improvement with glucosamine alone. Study authors speculate that long-term treatment with glucosamine may reduce dependence on NSAIDs and delay disease progression.

Glucosamine may cause mild gastrointestinal symptoms, as well as increased blood glucose, cholesterol, triglyceride and blood pressure. This supplement can increase eye pressure in people with glaucoma.

A 2018 review and metanalysis published in JAMAof all of the therapeutic agents used for knee arthritis long term, including analgesics, antioxidants, bone-acting agents, nonsteroidal anti-inflammatory drugs (NSAIDs), intra-articular injection medications such as hyaluronic acid and corticosteroids, symptomatic slow-acting drugs in osteoarthritis and putative disease modifying agents,  found that only glucosamine sulfate was associated with pain improvement. This also may be another answer to “What is the best supplement for arthritis?”

Arthritis Foundation recommended dosage: Capsules, tablets, liquid or powder (to be mixed into a drink); 1,500 mg once daily or in three divided doses to prevent stomach upset. Often combined with chondroitin. May take up to one month to notice effect.

Chondroitin Sulfate

Chondroitin is a component of human connective tissues found in cartilage and bone. In supplements, chondroitin sulfate usually comes from animal cartilage. Reduces pain and inflammation, improves joint function and slows progression of osteoarthritis (OA). Chondroiton is believed to enhance the shock-absorbing properties of collagen and block enzymes that break down cartilage. Helps cartilage retain water and may reverse cartilage loss when used with glucosamine.

The largest study to date, the 2006 Glucosamine/chondroitin Arthritis Intervention Trial (GAIT) looked at 1,600 people with knee OA. (See above under glucosamine for results.)

A separate 2011 study showed a significant improvement in pain and function in patients with hand OA using chondroitin alone.

A 2013 review of the evidence on use of chondroitin for OA concluded that chondroitin has a beneficial effect on different kinds of cells involved in osteoarthritis and that it is an effective and safe treatment option for patients with OA.

Chondroitin and glucosamine supplements appear to be safe and constitute another good answer to the question, “What is the best supplement for arthritis?”

Chondroitin taken with blood-thinning medication like NSAIDs may increase the risk of bleeding. If you are allergic to sulfonamides, start with a low dose of chondroitin sulfate and watch for any side effects. Other side effects include diarrhea, constipation and abdominal pain.

Arthritis Foundation Recommended Dosage: Capsules, tablets and powder; 800 mg to 1,200 mg daily in two to four divided doses. Often combined with glucosamine. Allow up to one month to notice effect.

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CBD (Cannabidiol)

Research has shown that CBD interacts with the body’s endocannabinoid system, which plays a role in regulating pain and inflammation. CBD may also help reduce the production of inflammatory cytokines, which are molecules that contribute to inflammation in the body.

Though research to date has been somewhat limited, both animal and human studies have shown positive effects.

In a 2019 study published in the journal European Journal of Pain, researchers found that CBD gel applied to the skin significantly reduced joint swelling and pain in rats with arthritis. The study suggested that topical CBD may be a safe and effective treatment for arthritis-related pain and inflammation in humans.

In a 2020 study published in the journal Pain Medicine, researchers found that CBD treatment improved pain and sleep in patients with rheumatoid arthritis. The study suggested that CBD may be a promising therapeutic option for management of pain and other symptoms in patients with rheumatoid arthritis.

A 2020 study published in the journal Cell Death and Disease concluded that “CBD possesses anti-arthritic activity and might ameliorate arthritis via targeting synocial fibroblasts under inflammatory conditions.”

A 2022 study published in the Journal of Cannabis Research found that CBD se was associated with improvements in pain, physical function,and sleep quality. The majority of respondentsreported a reduction or cessation of use of other medications after CBD use.

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Other Beneficial Supplements for Arthritis

Other supplements that have evidence of effectiveness for arthritis include: Borage oil, Boswellia, Bromelain, Cat’s Claw, Devil’s claw, DMSO, Ginkgo, GLA, MSM, Pycnogenol, St. John’s Wort and Stinging Nettle.

Find Providers Who Treat Arthritis with Nutrition

Conclusion

There are many supplements that can reduce arthritis pain and functional limitations. All of them are less risky than using pharmaceuticals for pain relief. The supplements not only reduce pain, they appear to have a beneficial overall biological effect on the disease process.

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My last experiment for treating residual Lyme/MSIDS arthritis pain has been an elimination diet to determine what is causing the inflammation/pain.  This is quite a process but certainly an entirely new education on food and the body.  Again, what works for one doesn’t work for another but in my case food is a huge player.

So far I’ve discovered I can not tolerate gluten or nightshades.  I’ve already limited sugar, grains, and alcohol.  Still trying to figure out if there is any dairy I can partake of as well as nuts/seeds and other grains or beans.

One thing is for sure: if you suffer with enough pain you can give up almost anything!

Category:

Herbs, Inflammation, Pain Management, Supplements, Treatment

LDN For Lyme

https://www.treatlyme.net/guide/low-dose-naltexone-lyme-disease

Updated: 3/21/23

About Low-Dose Naltrexone for Lyme

Low-dose naltrexone (LDN) is very useful in Lyme disease. This low-cost medicine can

  • improve nerve, muscle, and inflammation pain,
  • decrease autoimmune illness triggered by Lyme,
  • improve mast cell activation symptoms,
  • lower cytokine inflammation, and
  • improve immune system function by increasing TRegs to balance Th1 and Th2.

In this article, I review the science and method for how LDN works. I describe how to use it in Lyme disease, and I review potential side effects.  (See link for article & video)

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Category:

Inflammation, Lyme, Pain Management, Sleep, Supplements, Treatment