Archive for the ‘Detoxing’ Category

Aluminum in the Brain in Multiple Sclerosis: Regulatory and Funding Agencies Silent, Complicit

https://jameslyonsweiler.com/2018/08/18/aluminum-in-the-brain-in-multiple-sclerosis-regulatory-and-funding-agencies-silent-complicit/

By James Lyons Weiler in Cures August 18, 2018

https://jameslyonsweiler.com

MEDICAL SCIENCE proceeds along a hierarchy of evidence; often, patients are studied individually (case studies), or a small collection of patients are examined and characterized together (case series studies). Case series studies typically have smallish sample sizes and it is generally understood that larger studies will be necessary to determine more accurately the characteristics being studied.

In a new case series study, brain tissue from 14 donors with a diagnosis of MS was studied in a case series by Mold et al (2018) using transversely heated graphite furnace atomic absorption spectrometry. The study found high aluminum content (>10 ug/g dry weight) in all areas of the brain studied, with some areas exceeding 50 ug/g. They found aluminum both with cells and in the interstitium between cells. They found aluminum co-localised with structures known to be present in Secondary Progressive Multiple Sclerosis (SPMS) in the frontal cortex of one donor with SPMS.

There are a number of critical lines of evidence that make this fundamental finding critically important. Patients with MS have lower amounts of aluminum in their hair, suggesting depressed detoxification, and higher amounts are found in urine on chelation challenge testing (Fulgenzi et al., 2014). Chelation with EDTA is known to significantly reduce aluminum intoxication (Fulgenzi et al. 2014), and consumption of silica-rich mineral waters also increase urinary excretion of aluminum from patients with SPMS (Jones et al., 2017).

Extremely plausible direct mechanisms of the cause of MS from aluminum are known and animal studies routinely induced MS using aluminum hydroxide injections. So much evidence exists that points to aluminum as a source of strange new conditions of unknown causes, such as MMF and Gulf War Syndrome, one would think that calls to reconsider the use of aluminum in vaccines would be answered. The same team had previously found high amounts of aluminum in the brains of people with autism, and and in patients with Alzheimer’s disease. The latter result, while also important, is not surprising, as it has long been known that amyloid is part protein and part aluminum. Finally, when France brought on HepB vaccination, cases of MS following vaccination increased; when they stopped recommending the HepB vaccine, which contains aluminum hydroxide, the rate of HepB vaccine-associated MS cases dropped to near zero.

francems

Complicity

What is surprising is the lack of action on the part of the US FDA to put an end to the use of this dangerous metal in vaccines, and that the NIH is not funding more studies like this. NIH should fund studies to determine how to most safely remove aluminum from anyone exposed via vaccines; brain stem amyloidosis is a non-trivial concern. Approaches like ketogenic diet, silica-rich mineral waters, hyperbaric oxygen, EDTA, intranasal insulin and intranasal deferoxamine (to prevent brain stem amyloidosis) should all be tested in randomized clinical trails in clinical populations known to be afflicted with aluminum intoxication (autism, Alzheimer’s, MS).

What is also surprising is that the CDC and ACIP remain blithe to the morbidity and mortality their continued approval of vaccines that contain metals like aluminum and mercury. They make decisions on behalf of us all, and yet every member of ACIP with the exception of one military member has conflicts of interest with vaccine manufacturers. ACIP should review all of the literature on aluminum and make recommendations on how to phase it, and thimerosal, out of vaccines completely.

Further inaction on the part of these regulatory and funding agencies, and active denialism at this point will surely be seen by future generations as both callous disregard, and where conflicts of interest reside, complicity.

The study, conducted at the Keele University, was funded in part by the Children’s Medical Safety Research Institute.

References

Jones K et al. EBioMedicine. 2017 Urinary Excretion of Aluminium and Silicon in Secondary Progressive Multiple Sclerosis. 26:60-67. doi: 10.1016/j.ebiom.2017.10.028.

Fulgenzi A, Vietti D1, Ferrero ME. Aluminium involvement in neurotoxicity. Biomed Res Int. 2014;2014:758323. doi: 10.1155/2014/758323.

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**Comment**

https://www.nationalmssociety.org/Symptoms-Diagnosis/Other-Conditions-to-Rule-Out/Lyme-Disease

Lyme disease can cause delayed neurologic symptoms similar to those seen in multiple sclerosis (MS) such as weakness, blurred vision caused by optic neuritis, dysesthesias (sensations of itching, burning, stabbing pain, or “pins and needles”), confusion and cognitive dysfunction, and fatigue. Lyme disease symptoms may also have a relapsing-remitting course. In addition, Lyme disease occasionally produces other abnormalities that are similar to those seen in MS, including positive findings on magnetic resonance imaging (MRI) scans of the brain and analysis of cerebrospinal fluid (CSF).

These similarities in symptoms and test results have led some people with MS to seek testing for the presence of antibodies to Borrelia, to determine if their neurologic symptoms are the result of Lyme disease or truly MS. The distinction is important because Lyme disease, especially when treated early, often responds to antibiotic therapy, whereas MS does not.

Studies examining Lyme disease & MS
Two studies have examined the overlap in diagnosis of MS and Lyme disease. The studies were conducted in parts of Long Island, New York, an area where Lyme disease is endemic, or regularly found.

In the first study, people who had Borrelia antibodies in their blood as well as a variety of neurologic symptoms considered to be “MS-like,” were evaluated with MRI, evoked potentials (EP) and CSF analysis, including a test for the presence of Borrelia antibodies in the spinal fluid.

While those with the MS-like illness had the highest incidence of abnormal MRIs and were the only ones among those studied to have abnormal EP and oligoclonal bands in their spinal fluid (indicating an abnormal immune response), they did not prove to have any Borrelia antibody in their spinal fluid.

The researchers concluded that the few patients with the MS-like symptoms probably had these symptoms due to MS and had also been exposed to the Borrelia bacterium.
A companion study looked for the presence of Borrelia antibodies in the blood of 100 people with the diagnosis of possible MS. Of 89 people who in fact turned out to have definite MS, only one had Borrelia antibodies. The researcher concluded that “…infection with Borrelia is infrequent in MS patients who live in an endemic area. Lyme disease is unlikely to be a significant factor in the differential diagnosis of MS.” Furthermore, the presence or antibodies to Borrelia does not prove that Borrelia is causing the neurological symptoms, only that there has been previous infection with the organism.

Just remember, “rare” is only “rare” if it isn’t you.

 

Methylation – What You Need to Know

https://vitalplan.com/blog/methylation-what-you-need-to-know?

Methylation: What You Need to Know

by Dr. Bill Rawls | Posted June 9, 2018

Methylation-What-you-need-to-know
If you haven’t yet heard the term methylation, there’s a good chance you’ll soon start hearing it a lot more. Many people are beginning to clue into the importance of this biochemical process, which is a key component of overall wellness, and yet myths and misconceptions are more common than facts. Understanding methylation, and knowing how to optimize it, can give you an edge on staying healthy as you age.
So what is methylation? In biochemical terms, methylation is when a “methyl group” consisting of three hydrogen atoms and one carbon atom are linked to another molecule. Attaching a methyl group to an organic molecule (a chemical compound that contains carbon) makes it less reactive.
In more laymen terms, methylation is a process of making molecules more stable, which is important for a wide range of metabolic functions in the body. For starters, it balances hormone and neurotransmitter activity, and regulates protein synthesis and cellular energy. It processes DNA/RNA, the molecules that are responsible for storing and reading our genetic information, and repairs DNA. And it optimizes the functions of T-cells, white blood cells that play a key role in immune response.
Methylation also helps neutralize toxic substances: When methyl groups attach to organic toxins such as heavy metals, it reduces their toxicity and allows for easier removal from the body. When you consider that the modern world is loaded with higher concentrations of artificial toxins than ever before in history, maintaining optimal methylation is increasingly vital.
One of the most important roles of methylation is regulating the expression of genes. At any given time, you are using only about 1% of your genetic material; the rest of it is in “off” mode. But there are certain factors notorious for turning on “bad” genes that are associated with chronic illness, many of which are unique to the modern world. These include eating a poor diet high in processed food products, exposure to environmental toxicants, dealing with chronic stress, and having a sedentary lifestyle.
This is where methylation comes in — the way the body turns off “bad” genes is by attaching methyl groups to genetic material. Of course, if you don’t change your diet and lifestyle, the bad genes will turn on and/or stay on. Keep stressing your genes, and all the methyl groups in the world aren’t going to help you stay well.

The role of poor methylation in chronic illness

This is a huge misconception: People with symptoms of chronic illness — typical ones being fatigue, neurological symptoms, mood disorders like anxiety, and insomnia, to name a few — are being told that poor methylation is the cause of their illness. But in fact, it’s those same stressors that activate bad genes that increase susceptibility to illness; poor methylation just compounds the problem.

The Western diet is the biggest culprit. The body relies on a steady stream of methyl donors from certain foods to support the metabolic functions that are dependent on methylation. (Methyl donors are any substance that can transfer a methyl group — three hydrogen atoms and one carbon atom — to another substance.) It can use a variety of methyl donors, but the four most important components are methionine (an amino acid) and the B vitamins: methylfolate (B-9), B-12, and B-6.

Unfortunately, modern grain- and meat-based diets are very poor sources of methylfolate and other B vitamins. Food companies often try to compensate for the loss of natural folate by adding folic acid to their products, but it’s not an adequate substitute. What’s more, people who over-consume processed foods tend to develop gastrointestinal problems and lose the ability to produce a substance called intrinsic factor, which is essential for absorption of vitamin B-12.

Genetics also play a role in methylation proficiency. About 50% of the population carries a mutated gene (MTHFR) for an enzyme called 5-MTHF reductase. This gene is necessary to convert homocysteine (an amino acid most abundant in meat) into methionine, an amino acid that’s essential for the methylation process. About 40% of the population carries one MTHFR mutation, and 12% of the population carries a double mutation.

Having MTHFR mutations, however, may be less of a factor in chronic illness than some experts suggest. The evidence linking concerns such as myalgic encephalomyelitis/chronic fatigue syndrome, fibromyalgia, and Parkinson’s disease to the presence of a mutated 5-MTHF reductase gene is mild at best. Scientific investigations have shown only a very slight increased incidence of chronic illnesses in affected individuals.

That’s because this genetic pathway is only one of a variety methylation pathways. The human body would never rely on a single option for a function like methylation which is so essential for life. In addition, for most of history, humans consumed large amounts of plant matter that provided all the components necessary for methylation (methionine, B-9, B-12, and B-6). It’s only in recent history, as our diet has become more plant- and nutrient-deficient, that this particular genetic methylation pathway has become “essential.”

How to know when it’s time to test

People often ask which symptoms indicate they should get tested for poor methylation, but there are no pure telltale signs. My answer is, if you have classic symptoms of chronic illness such as fibromyalgia or ME/CFS, and you eat a lot of processed foods and very few vegetables, it’s pretty safe to assume have poor methylation.

The biggest reason to have the test is to determine whether you have a double mutation, in which case supplementation with natural folates may be valuable. Determining whether you have a MTHFR mutation requires a simple blood test that costs about $150.

Checking for elevations of homocysteine in your blood can tell you the degree of the problem: The higher your homocysteine levels, the lower the formation of methylfolate for making methionine, if methylation mutations are present. More than anything else, elevations of homocysteine indicate over-reliance on grains and meat as a food source.

6 ways to support proper methylation

Maintaining proper levels of methylation is important for health, but it must be part of a more comprehensive strategy. Again, nothing can balance the damage that comes from eating a nutrient-poor diet, living in a toxic environment, allowing stress to get the best of you, and sitting all day. Follow the simple steps below to help ensure optimal methylation, and whether or not you carry a MTHFR mutation will become a non-issue:

1. Eat your veggies.


Focus especially on dark green leafy vegetables such as spinach and kale, as well as asparagus, broccoli, cauliflower, and peas and beans (preferably sprouted). A healthy, plant-based diet containing these foods is the number one way to ensure you take in plenty of methylfolate, one of the primary methyl donors.

2. Get plenty of B vitamins.


Folate is a B vitamin, but vitamins B6 and B12 can be important methyl donors, too. You’ll find them in salmon, eggs, nuts and seeds, plus bananas, avocados, and soy.

3. Look for active forms of B-vitamin methyl donors.


If you take daily vitamin and mineral supplements to support your health, check ingredient lists to be sure they contain bioactive forms of the B vitamin methyl donors, which means they’re in a form your body can actually use. Here’s what they’ll look like on the label:

  • Folate (active forms: 5-Methyltetrahydrofolate or l-Methylfolate) Note that folic acid found in most multivitamin products is not satisfactory. It is not absorbed and utilized in the body properly, especially if you have a MTHFR mutation. This is particularly true if you are pregnant, in which case supplement with methylfolate, instead of folic acid, and consume plenty of leafy greens.
  • B6 (active form: Pyridoxal 5-Phosphate)
  • B12 (active forms: Methylcobalamin or Hydroxocobalamin)

4. Supplement with glutathione, if needed.


Glutathione is an essential antioxidant and another methyl donor, and it’s important for a myriad of processes in the body. Supplementing isn’t as necessary for young, healthy people, but chronic illness and aging put extra pressure on the body, so extra glutathione can be beneficial. Taking SAMe is another way to support the methylation process, but again, it’s unnecessary for young, healthy people, or if you’re getting adequate bioavailable B vitamins.

5. Consider restorative herbs.


Opt for herbs that support your immune system, microbiome and other functions such as andrographis, Japanese knotweed, milk thistle and sarsaparilla. “Any of the restorative herbs will help counteract a wide spectrum of stress factors in the body, and therefore help take pressure off of detoxification and healing systems,” Dr. Rawls says. “Cordyceps and reishi are also good examples, because they support immune system functions.”

6. Stay active, manage stress, and cut back on alcohol.


It’s common sense that living a healthy lifestyle helps keep everything in your body running smoothly. But research has started connecting the dots between lifestyle factors such as sedentary behavior, stress, and toxins such as alcohol with changes in DNA methylation.

Proper methylation impacts so many health systems of the body, and the simple steps outlined above can help support and enhance the process — MTHFR gene mutation or not. Enjoy your favorite produce, take steps to stay active and keep stress in check, and supplement with the right nutrients and herbs, and you’ll be paving a path toward a long, healthy, vibrant life.

References
1. Richardson, B. “DNA methylation and autoimmune disease.” Clinical Immunology 2003 Oct;109(1):72-9
2. de Vega, WC et. al. “DNA Methylation Modifications Associated with Chronic Fatigue Syndrome.” PLoS One 2014; 9(8): e104757.
3. Sokratous, M. et. al. “Deciphering the role of DNA methylation in multiple sclerosis: emerging issues.” Autoimmunity Highlights. December 2016, 7:12
4. Varela-Rey, M. et. al. “Alcohol, DNA methylation, and cancer.” Alcohol Research. 2013;35(1):25-35.
5. Phillips, T. “The Role of Methylation in Gene Expression.” Nature Education 1(1):116
6. Jones, MJ et. al. “DNA methylation and healthy human aging.” Aging Cell. (2015) 14, pp 924-932
7. Jones, Meaghan J. et. al. “DNA methylation and healthy human aging.” Aging Cell (2015) 14, pp 924-932
8. De Vocht, F. et al. “DNA methylation from birth to late adolescence and development of multiple-risk behaviours.” Journal of Affective Disorders. 2018 Feb; 227: 588–594.

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For more:  https://madisonarealymesupportgroup.com/2018/03/23/altered-dna-methylation-mental-illness-lyme-msids/

https://madisonarealymesupportgroup.com/2018/04/09/3-part-series-on-genetic-mutations/

 

 

Study Shows Dead Lyme Debris Persists in CNS Despite Antibiotics and Causes Inflammation

https://www.ncbi.nlm.nih.gov/m/pubmed/29922241/

Primary Human Microglia Are Phagocytically Active and Respond to Borrelia burgdorferi With Upregulation of Chemokines and Cytokines.

Greenmyer JR, et al. Front Microbiol. 2018.

Abstract

The Lyme disease causing bacterium Borrelia burgdorferi has an affinity for the central nervous system (CNS) and has been isolated from human cerebral spinal fluid by 18 days following Ixodes scapularis tick bite. Signaling from resident immune cells of the CNS could enhance CNS penetration by B. burgdorferi and activated immune cells through the blood brain barrier resulting in multiple neurological complications, collectively termed neuroborreliosis. The ensuing symptoms of neurological impairment likely arise from a glial-driven, host inflammatory response to B. burgdorferi.

To date, however, the mechanism by which the bacterium initiates neuroinflammation leading to neural dysfunction remains unclear. We hypothesized that dead B. burgdorferi and bacterial debris persist in the CNS in spite of antibiotic treatment and contribute to the continuing inflammatory response in the CNS.

To test our hypothesis, cultures of primary human microglia were incubated with live, antibiotic-killed and antibiotic-killed sonicated B. burgdorferi to define the response of microglia to different forms of the bacterium. We demonstrate that primary human microglia treated with B. burgdorferi show increased expression of pattern recognition receptors and genes known to be involved with cytoskeletal rearrangement and phagocytosis including MARCO, SCARB1, PLA2, PLD2, CD14, and TLR3. In addition, we observed increased expression and secretion of pro-inflammatory mediators and neurotrophic factors such as IL-6, IL-8, CXCL-1, and CXCL-10. Our data also indicate that B. burgdorferi interacts with the cell surface of primary human microglia and may be internalized following this initial interaction.

Furthermore, our results indicate that dead and sonicated forms of B. burgdorferi induce a significantly larger inflammatory response than live bacteria. Our results support our hypothesis and provide evidence that microglia contribute to the damaging inflammatory events associated with neuroborreliosis.

___________________

**Comment**

The study in the following link corroborates the above study in that it did not find active CNS infection with Lyme encephalopathy:  https://www.medscape.com/viewarticle/891992

The following short video shows phagocytosis in action.  For those of my vintage, think of Pac Man gobbling up things in its path.  This is exactly what our immune cells (macrophages or white blood cells) do.  Notice that “special digestive enzymes” shred the bacterium into pieces.  This is why enzyme therapy can help Lyme/MSIDS patients – both digestive and systemic enzymes can help in numerous ways – one of which is by shredding the bacteria, and cleaning the blood of debris.  According to the above study, this debris is very probably ONE reason we have high inflammation, pain, and symptoms.  Anything you can do to clear out that debris is helpful.

Immune Cells Eating Bacteria (Phagocytosis)

Animation by: Fusion Medial Animation (www.fusionanimation.co.uk) Microscopy by: Timelapse Vision (http://timelapsevision.com)

This video describes the structure and function of microglia.

By Matt Jensen. Created by Matthew Barry Jensen.

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For more on Enzymes:  https://madisonarealymesupportgroup.com/2016/04/22/systemic-enzymes/

https://madisonarealymesupportgroup.com/2018/03/05/how-proteolytic-enzymes-may-help-lyme-msids/

Lactoferrin, an iron-binding milk glycoprotein has also been found to help due to borrelia’s ability to hijack our plasminogen system allowing it to penetrate tissue barriers:  https://madisonarealymesupportgroup.com/2018/05/03/lactoferrin-for-lyme/

DMSO & MSM may also help certain patients due to their anti-inflammatory, anticoagulant, oxygenating, free radical scavenging, detoxifying, and antiparasitic properties.  Please read this article to understand both substances better.  https://madisonarealymesupportgroup.com/2018/03/02/dmso-msm-for-lyme-msids/

And, as always, please work with your medical practitioner and discuss ALL treatment ideas.  There are medical contraindications on nearly every substance and you need to be privy to them.

Recover From Brain Fog & Lyme Disease Naturally

https://www.linkedin.com/pulse/recover-from-brain-fog-lyme-disease-naturally-gary-blier/

Recover From Brain Fog & Lyme Disease Naturally

Published on June 26, 2018
Gary Blier
Founder, Advanced Cell Training

When most people think of Lyme disease, it conjures up thoughts of rashes, flu-like symptoms, and joint pain. However, there are a significant number of Lyme sufferers who also experience brain fog: agonizing neurological symptoms that leave them feeling drained, irritable, confused, and cognitively lagging.

Brain fog is one of the most common psychiatric manifestations of Lyme Disease. In fact, it’s estimated that 70% of individuals affected by Lyme show signs of cognitive decline or memory loss.

While you may be familiar with brain fog within the Lyme community, you may not be aware of what it is or why it happens. We’ll break it all down for you in this article and provide you with natural solutions you can carry out at home to lift the fog that robs you of a clear mind.

What is Brain Fog?

Brain fog is a term given by those whose brain function is underperforming compared to a normal, healthy brain. It can range from a mild case of “cloudiness” to a more severe case that makes it difficult to perform basic tasks.

Brain fog symptoms include:

Memory loss
Slowed processing
Difficulty thinking or making decisions
Poor concentration
Mood swings
Confusion
Sleep disturbances
Decreased problem-solving abilities
Easily overwhelmed
Low energy or fatigue
Headaches
Depersonalization or dissociation (i.e., loss of emotional connection to others and life)
Other brain fog indicators may include feeling fuzzy-headed, unmotivated, melancholy, or irrational for no apparent reason. It’s also not uncommon for anxiety and depression to accompany brain fog, especially in cases of prolonged illness.

Additionally, brain fog symptoms can wax and wane during periods of high stress, exposure to electromagnetic frequencies and overly stimulating environments, hormonal changes, and during a herxheimer reaction. Symptoms can even intensify with certain moon cycles.

Your Brain on Lyme

Scientists are still trying to understand Lyme disease and how it affects the brain, but several studies have already concluded that Lyme bacteria can impact every aspect of the brain. Medical experts also agree that Lyme and coinfections cause the brain to swell, which can result in neurological or neuropsychiatric symptoms such as brain fog.

One of the most common causes of brain fog are the Lyme pathogens themselves, otherwise referred to as spirochetes. These corkscrew-shaped bacteria deeply embed themselves inside tissues, neurons, and cells. They can cross over the blood-brain barrier and wreak havoc on brain receptors and neural pathways.

When these pathogens die off, they excrete harmful endotoxins and exotoxins that inhibit brain function. If you do not detox properly, these toxins can accumulate and cause brain fog or damage brain tissue. The very presence of such toxins trigger the immune system to go into hyperdrive, releasing more cytokines into the blood, fueling inflammation within the brain and body. Cytokines are small proteins that are instrumental in cell signaling.

To overcome Lyme disease and brain fog, it’s crucial to address all underlying inflammation by making modifications to one’s diet and lifestyle.

Natural Brain Fog Recovery Tips

Get on the road to recovery from Lyme brain fog by taking inventory of the following areas:

Restful Sleep

One of the most significant neurological challenges for people with Lyme is insomnia. More than just a frustrating symptom, disturbed sleep patterns can interfere with healing by damaging the immune system, allowing toxins or pathogens to take root in the body. Insufficient sleep can also raise cytokine chemicals and quinolinic acid in the body that can lead to inflammation and worsen neurological symptoms.

Getting adequate sleep is key to Lyme recovery. Remember, it’s not just about the hours you clock every night, but also the quality of sleep that matters. Your brain and immune system do most of their healing when you are in a deep sleep, so it’s advised to get sleep around 10:00 pm and wake after about 7-8 hours of good sleep.

Need extra help in this department? Ask a medical practitioner about checking your hormones or thyroid levels to see what could be preventing you from getting enough zzz’s.

Anti-Inflammatory Diet

To support your brain health, try an anti-inflammatory diet to give your brain and body the nutrients it needs to heal. Buy organic as often as possible because toxic GMOs and pesticides can cause inflammation and put unnecessary stress on your body.

Eliminate these common offenders from your diet: caffeine, alcohol, refined carbohydrates, gluten, and sugar. All of these are enemies of brain fog and can impair brain function. It’s also best to avoid these substances until after your Lyme recovery.

Click here to read a great article on the top 15 anti-inflammatory foods that can transform your health:  https://draxe.com/anti-inflammatory-foods/

Also, cut out neuro-inflammatory saturated fats and instead up your intake of good or monounsaturated fats. Olive oil, nuts, avocado, and some types of fish have been shown to enhance memory and cognitive function, according to Harvard Medical School.

De-Stress Your Brain

High levels of cortisol, the body’s “stress hormone” have been linked to brain fog. Chronically elevated cortisol can disrupt your symphony of hormones that work intrinsically to keep your body in check. When one hormone falls too low, another one overcompensates to restore harmony.

Routinely check your cortisol levels (preferably via a saliva test) to ensure your levels are in balance. Actively pursue activities that reduce stress and declutter your mind, whether it be meditation, prayer, music, or your favorite hobby. Give yourself permission to unplug from the grid and relax.

Detox, Detox, Detox

Brain fog is often a sign of built-up toxins–Lyme, mold, parasites, or yeast–in the blood and intestines. Consider infrared sauna sessions, or doing light exercise or yoga to stimulate your lymphatic system. Get those toxins moving out of your body!

You may also speak to your healthcare providers about supplements you can take to support your detox pathways. Bentonite clay, activated charcoal, and juice cleanses are generally safe options for cleaning out the sludge.

Another way to help flush toxins out is to stay well-hydrated throughout the day. Multiply your body weight by 67%. The resulting number is the number of ounces of water you should drink daily. For example, a 100-pound person would need 67 ounces of water. Divide that by 8 – the number of ounces in a glass of water – and the result is roughly 8 glasses of water per day. Most of us fall far short of this amount.

Self-Healing for Lyme Disease and Brain Fog

You might also need extra support recovering from Lyme disease and brain fog. Advanced Cell Training (ACT) offers a self-healing program that enables your body’s own awesome ability to kill microorganisms – even in the brain. With ACT, you can train your own immune system to respond appropriately to spirochetes, parasites, and coinfections. This simple training process has helped thousands over the last 20 years overcome health issues. Basically, we point out where your body is going wrong and show it how to self-correct and get things back on track.

For more on ACT:  https://advancedcelltraining.com

 

Yes, You Do Sweat Out Toxins

https://articles.mercola.com/sites/articles/archive/2018/05/30/sweating-out-toxins.aspx?

Yes, You Do Sweat Out Toxins

By Dr. Mercola, May 30, 2018  

Story at-a-glance

  • Sweating in a sauna is one of the simplest strategies to reap big health rewards, including releasing heavy metal toxins, urea, bisphenol-A and phthalates as well as improving blood flow, reducing blood pressure and improving cognition
  • Sauna use improves mitochondrial biogenesis, optimizes heat shock proteins and reduces your risk of cardiovascular events and stroke
  • Research data finds chemicals in your sweat may communicate fear or disgust to those around you
  • Sweating is not a fitness end goal; this means while sweating in a sauna may feel the same as sweating during your workout, it does not translate to the same cardiovascular and muscular fitness benefits

When it comes to your health, sometimes the simplest strategies can have a tremendous impact. Sweating in a sauna is one simple change with many health benefits, including the ability to reduce cardiovascular risk and improve mitochondrial function. It also correlates well with a reduction in the risk for dementia.

A Finnish proverb says, “The sauna is Finland’s medication … and a poor [person’s] apothecary.”1 Saunas have been used for nearly 2,000 years in Finland for stress relief and to improve health. Not surprisingly, much of the research on the health benefits of saunas comes from Finland, a country where saunas are nearly as common as television sets.2 They’re often found in private homes, offices and factories, and are an integral part of Finnish life.

In addition to offering cardiovascular and neurological benefits, they are being used by athletes for post-workout muscle relaxation and as a means of improving athletic performance. Another important aspect to sauna use has been detoxification. While there has been more than adequate research demonstrating the ability of sweating in a sauna to detoxify the body of heavy metals and other toxins, one letter published in the Journal Environmental International has renewed the debate over its effectiveness.3

Experts Call Detox Sweating a Myth

Some experts teach that your liver and kidneys are the only way your body has of removing toxins.4 In essence, they believe using a sauna to detoxify from environmental toxins and heavy metals is nothing more than a myth. In making the argument, some have indicated there is usually a grain of truth to the heart of every myth, believing toxic sweat is no exception.

The authors of the correspondence5 published in the journal Environmental International suggest the amount of toxins the body is capable of releasing through sweat is minuscule, and that the amount of pollutants — such as persistent organic compounds such as pesticides, flame retardants and now-banned polychlorinated biphenyls (PCBs) — in the human body is so low they’re essentially meaningless.

Yet these toxins and known carcinogens are banned from use because they trigger disease. According to the lead author, a typical person doing 45 minutes of high-intensity exercise could sweat a total of 2 liters each day, including normal everyday perspiration. This sweat would contain less than one-tenth of a nanogram of the pollutants discussed.

Hence, he believes there is no way to sweat enough to get rid of even 1 percent of the chemicals you ingest in your food in a single day.6 Ironically, and perhaps tellingly, this statement completely contradicts the claim that the toxic burden is essentially meaningless to begin with.

Another writer wrote an infrared sauna was nice and left her feeling euphoric after sitting in 30 minutes, but she believed the feeling was similar to an endorphin rush after working out,7 and that aside from the feelings of euphoria there was no science to back up the idea the sauna aided in detoxification. While these articles are circulated and read, they do not reflect the body of scientific and research evidence demonstrating the effectiveness of saunas to assist the body in eliminating environmental toxins and heavy metals.

Sweating Does Release Toxins From Your Body

Mixed with your sweat is a substance called urea, for which urine is named. In a paper published8 in the Journal of Biological Chemistry, researchers estimated up to 1.12 milligrams (mg) of urea is dissolved in every cubic centimeter of sweat. While this sounds like a small amount, the average person sweats up to 700 cubic centimeters of liquid each day, which means urea excreted in your sweat is responsible for up to 7 percent of your daily elimination of urea.9

Research has also determined that metals are excreted in measurable amounts, and many researchers consider sweating a safe and effective way to eliminate arsenic, cadmium, lead and mercury.10 This meta-analysis considered 24 published studies in which sweat collection and concentration were analyzed. They found individuals with a higher burden of toxins would generally sweat amounts exceeding plasma or urine concentrations.

These studies determined dermal excretion through sweating could match or surpass urinary excretion. Notably, cadmium was more concentrated in sweat than in blood plasma and mercury levels could be normalized with repeated sauna use.11 Another study evaluated the blood, urine and sweat from 20 individuals and analyzed them for approximately 120 compounds, which were found in varying amounts in each of the different fluids. According to the authors:12

Many toxic elements appear to be preferentially excreted through sweat. Presumably stored in tissues, some toxic elements readily identified in the perspiration of some participants were not found in their serum. Induced sweating appears to be a potential method for elimination of many toxic elements from the human body.”

Bisphenol-A (BPA) is a ubiquitous chemical contaminant associated with a number of adverse human health conditions. In a study designed to assess the relative concentration of BPA in blood, urine and sweat, researchers found BPA could be identified in the sweat or 80 percent of the participants, even in some who had no BPA detected in serum, blood or urine.13

They concluded biomonitoring using blood or urine may underestimate the total burden, and sweat analysis should be considered as it appeared to be useful for elimination of BPA.

Chemicals in the phthalate family are found in everyday consumer products, resulting in high exposure for some individuals and groups. Multiple studies have demonstrated statistically significant relationships between exposure to phthalates and disease. In one study,14researchers evaluated the effectiveness of excretion of phthalates and metabolites through sweat.

They found some phthalates were measurable in sweat but not serum suggesting retention and bioaccumulation. They concluded induced perspiration could be useful to facilitate elimination of toxic phthalate compounds, and that sweat analysis may help establish the existence of the bioaccumulation of 2-ethylhexl phthalate.15

Sweating Communicates Emotions

Although sweating is an important method of excreting waste products, researchers have discovered it also serves another function. Sweat leaves the body through one of three types of glands — apocrine, eccrine and apoeccrine glands. The latter were first discovered in 1987 and found only in the same places where apocrine glands exist.16

The human body will sweat as a means of regulating temperature. However, you may also begin to sweat when eating something spicy, or experiencing a highly charged emotional situation. Researchers have discovered emotion-induced sweating is a tool used for communication, as the scent you detect in the sweat will tell you how others are feeling.

In an experiment by Utrecht University,17 psychologists collected sweat samples from 10 men as they watched videos designed to stimulate feelings of fear or disgust. Thirty-six women were then asked to detect any emotional cues from the sweat samples. The scientists found when women smelled sweat produced during fearful situations, their own facial expressions suggested fear as well. The same was true when they smelled the sweat samples produce during situations meant to evoke disgust.

This suggested the sweat was an effective means of communicating an emotional state. Interestingly, the facial expressions made by the women while sniffing the sweat was independent of their subjective perception of the odor. Thus, a woman may show a look of disgust even if they reported the sample as pleasant. Similar results were found in other experiments, including one from Rice University when women exposed to sweat samples produced in a fearful situation performed better on word association tasks.18

In an experiment conducted by German psychologists and neuroscientists,19 sweat produced by men who were in an anxious state triggered women to make riskier decisions in a computer game. None of the studies determined whether people were aware of changes in their own behavior or decision-making as a result of exposure to sweat, but they do suggest sweat may communicate information about your mental state.

Sweating Cannot Replace Exercise

You sweat during intense exercise and while using a sauna, which may lead you to believe you can experience some of the same benefits using a sauna as you would doing intense exercise. Unfortunately, you’re not going to sweat off the pounds or build muscle in a sauna.

Sweating is not, in and of itself, a fitness goal. Sweating during intense exercise regulates internal temperature. Using the sauna may help improve athletic performance and recovery by boosting growth hormone secretion naturally,20 and definitely has additional benefits beyond excreting waste products from your body. However, it is important to include movement, strength training, flexibility and cardiovascular training in your fitness routine.

Saunas Do More Than Detoxify

Inside most of your cells are mitochondria that produce nearly 90 percent of the energy generated in your body, which is necessary for every muscle contraction and relaxation, biochemical cascade, cellular regeneration and more.

Your mitochondria also act as coordinators for programmed cell death, which helps rid your body of damaged cells that might otherwise turn into cancer. However, mitochondria are susceptible to damage from free radicals and require consistent regeneration. Sauna use places stress on your body in short bursts, which boosts mitochondrial biogenesis.21

Elevating your core temperature helps activate genes important for optimizing heat shock proteins (HSP) inside your cells. An accumulation of damaged HSP can lead to plaque formation in your brain or other vascular systems.22

HSP are involved in longevity and are important for preventing skeletal muscle atrophy. Researchers in Finland23 found men who use a sauna four to seven times per week for an average of 15 minutes had a 66 percent lower risk of developing dementia and 65 percent lower risk of Alzheimer’s disease, compared to those who use the sauna only once a week.

Sauna use may also improve brain function by lowering inflammation and blood pressure, thus improving vascular function and enhancing your feeling of relaxation and well-being. Research data24 demonstrates a link between heat exposure and brain-derived neurotrophic factor (BDNF).

This factor activates brain stem cells to convert into new neurons and triggers other chemicals promoting neural health. Exercising in the heat increases BDNF even further, suggesting heat stress, including sauna use, is beneficial for brain health.

Further research reveals men who used a Finnish-style, dry heat sauna seven times per week cut their risk of death from fatal heart problems in half, compared to those who used it only once a week.25 When confounding factors such as smokingblood pressure and cholesterol levels were factored in, the findings remained the same. The greatest benefits were found in those who stayed in a sauna for 19 minutes or more each session.26

This suggests the adaptations your body makes to heat stress, including improved blood flow to your heart and muscles, positively impact your heart health. Another study27 evaluating the effects of a sauna on over 1,600 men and women found it helps reduce stroke risk by lowering inflammation, reducing arterial stiffness and improving blood flow through the circulatory system. Those who used the sauna up to seven times per week reduced their risk by 62 percent.28

Choose Your Best Sauna Option and Take Precautions

There are several sauna options from which you can choose, including a Finnish sauna, far-infrared saunas and near-infrared saunas. The difference between the infrared saunas and the traditional Finnish sauna is the Finnish-style heats you from the outside in, where the infrared heats from the inside out. Near-infrared saunas have additional benefits as they penetrate your tissues more effectively and at wavelengths not absorbed by water.

The near-infrared range affects your health primarily through interaction with chromophores, light-absorbing molecules found in your mitochondria and water molecules. Near-infrared light also has healing and repairing properties, helping optimize other biological functions. For more information about the benefits to using near-infrared saunas and precautions you should take before using a sauna, see my previous article, “Spending Time in a Sauna Can Reduce Your Risk for a Stroke.”

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**Comment**

And don’t forget there’s ozone saunas.  Here’s a great article by Dr. Rowan on the effectiveness on ozone on Ebola. Of course he’s referring to blood ozone; however, ozonating the body via ozonated sauna would have many benefits as well:  http://www.docrowen.com/ozone-therapy.html