Archive for the ‘Bartonella’ Category

Interstitial Cystitis & Bladder Symptoms in Lyme & Bartonella

https://www.treatlyme.net/guide/interstitial-cystitis-lyme  (Article and video Here)

Updated: 10/13/23

Interstitial Cystitis and Bladder Symptoms

By Dr. Marty Ross

Some patients with Lyme disease and bartonella infection have symptoms similar to those seen in a bladder infection. These symptoms include

  • urge to urinate,
  • bladder pain and pain on urination,
  • bladder cramping, and
  • increased frequency of urination.

When these symptoms occur, a bladder infection should be ruled out by a healthcare provider. When it is ruled out, these symptoms are often the result of a condition called Interstitial Cystitis. Depending on a person’s age and other risk factors, a urologist may need to evaluate the bladder with a fiberoptic scope to assure that cancer is not present and to confirm a diagnosis of Interstitial Cystitis.

In this article I review the ways to support Interstitial Cystitis with natural medicines in a Lyme disease treatment.  (See link for article and video)

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Category:

Bartonella, diet and nutrition, Lyme, Supplements, Treatment

Analysis of Bacteria in Tropical Cattle Tick

https://link.springer.com/article/10.1007/s10493-023-00851-x

ResearchPublished: 

Analysis of the bacterial community in female Rhipicephalus microplus ticks from selected provinces in Luzon, Philippines, using next-generation sequencing

Sheane Andrea V. Hernandez, Saubel Ezrael A. Salamat & Remil L. Galay

Experimental and Applied Acarology (2023)Cite this article

Abstract

Analysis of the tick microbiome can help understand tick–symbiont interactions and identify undiscovered pathogens, which may aid in implementing control of ticks and tick-borne diseases. The tropical cattle tick Rhipicephalus microplus is a widespread ectoparasite of cattle in the Philippines, negatively affecting animal productivity and health. This study characterized the bacterial community of R. microplus from Luzon, Philippines, through next-generation sequencing of 16s rRNA. DNA was extracted from 45 partially engorged female ticks from nine provinces. The DNA samples were pooled per province and then sequenced and analyzed using an open-source bioinformatics platform. In total, 667 operational taxonomic units (OTUs) were identified. The ticks in all nine provinces were found to have Coxiella, Corynebacterium, Staphylococcus, and Acinetobacter. Basic local alignment search tool (BLAST) analysis revealed the presence of known pathogens of cattle, such as Bartonella, Ehrlichia minasensis, and Dermatophilus congolensis. The tick samples from Laguna, Quezon, and Batangas had the most diverse bacterial species, whereas the tick samples from Ilocos Norte had the lowest diversity. Similarities in the composition of the bacterial community in ticks from provinces near each other were also observed. This is the first study on metagenomic analysis of cattle ticks in the Philippines, providing new insights that may be useful for controlling ticks and tick-borne diseases.

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Category:

Bartonella, Ehrlichiosis, research, Ticks

Novel Treatment For Relapsing Lyme, Babesia, and Bartonella

https://www.mdpi.com/2076-2607/11/9/2301

Comparison of the Efficacy of Longer versus Shorter Pulsed High Dose Dapsone Combination Therapy in the Treatment of Chronic Lyme Disease/Post Treatment Lyme Disease Syndrome with Bartonellosis and Associated Coinfections

by 1,2,*, 2 and Phyllis R. Freeman2
Microorganisms 2023, 11(9), 2301; https://doi.org/10.3390/microorganisms11092301
Received: 8 August 2023 / Revised: 27 August 2023 / Accepted: 8 September 2023 / Published: 12 September 2023
(This article belongs to the Special Issue Bartonella and Bartonellosis: New Advances and Further Challenges)

Abstract

Twenty-five patients with relapsing and remitting Borreliosis, Babesiosis, and bartonellosis despite extended anti-infective therapy were prescribed double-dose dapsone combination therapy (DDDCT), followed by one or several courses of High Dose Dapsone Combination Therapy (HDDCT). A retrospective chart review of these 25 patients undergoing DDDCT therapy and HDDCT demonstrated that 100% improved their tick-borne symptoms, and patients completing 6–7 day pulses of HDDCT had superior levels of improvement versus 4-day pulses if Bartonella was present.
At the completion of treatment, 7/23 (30.5%) who completed 8 weeks of DDDCT followed by a 5–7 day pulse of HDDCT remained in remission for 3–9 months, and 3/23 patients (13%) who recently finished treatment were 1 ½ months in full remission.
In conclusion, DDDCT followed by 6–7 day pulses of HDDCT could represent a novel, effective anti-infective strategy in chronic Lyme disease/Post Treatment Lyme Disease Syndrome (PTLDS) and associated co-infections, including Bartonella, especially in individuals who have failed standard antibiotic protocols.
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Category:

Babesia, Bartonella, Lyme, research, Treatment

Case Report: Substantial Improvement of Autism in Child By Using Treatment For Vector Borne Infections

https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1205545/full

Case report: Substantial improvement of autism spectrum disorder in a child with learning disabilities in conjunction with treatment for poly-microbial vector borne infections

CASE REPORT article

Front. Psychiatry, 18 August 2023
Sec. Autism
Volume 14 – 2023 | https://doi.org/10.3389/fpsyt.2023.1205545
Amy Offutt1* Edward B. Breitschwerdt2
  • 1Heart and Soul Integrative Health, Marble Falls, TX, United States
  • 2Intracellular Pathogens Research Laboratory, Department of Clinical Sciences, and the Comparative Medicine Institute, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, United States

Poly-microbial vector-borne infections may have contributed to neuropsychiatric symptoms in a boy diagnosed with autism spectrum disorder. Targeted antimicrobial treatment resulted in substantial improvement in cognitive (such as learning disabilities, focus, concentration) and neurobehavioral (such as oppositional, defiant, anti-social, disordered mood, immaturity, tics) symptoms.

Conclusion

This teenage boy had a drastic improvement in his neuropsychiatric symptoms and in his academic standing, moving from special education services with accommodations to grade level academic standing without accommodations, to college acceptance. Progressive symptomatic improvement occurred only following targeted administration of antimicrobial agents directed at suspected, underlying, chronic infectious pathogens, namely the causative agents of bartonellosis and borreliosis. Further research is clearly needed to define if or the extent to which occult infections can contribute to neuropsychiatric illness, such as ASD.

(See link for full article)

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Category:

Autism, Bartonella, Lyme, Psychological Aspects, research, Treatment, Uncategorized

The Use of Natural Bioactive Nutraceuticals in the Management of Tick-Borne Illnesses

https://www.mdpi.com/2076-2607/11/7/1759

The Use of Natural Bioactive Nutraceuticals in the Management of Tick-Borne Illnesses

By Samuel M. Shor and Sunjya K. Schweig

Microorganisms 2023, 11(7), 1759; https://doi.org/10.3390/microorganisms11071759
Received: 14 May 2023 / Revised: 29 June 2023 / Accepted: 29 June 2023 / Published: 5 July 2023

Abstract

The primary objective of this paper is to provide an evidence-based update of the literature on the use of bioactive phytochemicals, nutraceuticals, and micronutrients (dietary supplements that provide health benefits beyond their nutritional value) in the management of persistent cases of Borrelia burgdorferi infection (Lyme disease) and two other tick-borne pathogens, Babesia and Bartonella species. Recent studies have advanced our understanding of the pathophysiology and mechanisms of persistent infections. These advances have increasingly enabled clinicians and patients to utilize a wider set of options to manage these frequently disabling conditions. This broader toolkit holds the promise of simultaneously improving treatment outcomes and helping to decrease our reliance on the long-term use of pharmaceutical antimicrobials and antibiotics in the treatment of tick-borne pathogens such as Borrelia burgdorferi, Babesia, and Bartonella.  (See link for full article)
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Go here for an excellent article on the above study which breaks it down for the lay person.  The following graph is within the article and will interest you:

For a full list of all 30+ bioactive nutraceuticals, see Appendix A. Summary of Clinical Impact.

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Category:

Babesia, Bartonella, Herbs, Lyme, research, Supplements, Treatment