Aluminum Revisited: No Enhanced Seroprotection & Raises Risk of Infection

January 8, 2024

https://popularrationalism.substack.com/p/systematic-review-finds-no-evidence?

Systematic Review Finds No Evidence of Enhanced Seroprotection from Aluminum Adjuvants in Vaccines

With no evidence of benefit, it is medical malfeasance and misinformation to claim they help vaccines induce an immune response in humans.

 
JAMES LYONS-WEILER
DEC 19, 2023
 

A systematic review of 102 studies on the biological effects of aluminum adjuvants compared to placebos in humans found aluminum-containing vaccines (ACVs) failed to provide superior seroprotection and, according to the authors, leaving recipients at increased potential risk of adverse events known to exist with aluminum exposure and zero benefit.

After noting that post-study vaccination of clinical trial participants makes it impossible to assess them long-term health consequences of ACVs (“aluminium adjuvant has been administered to both the experimental and control groups in the vast majority of randomised clinical trials on HPV vaccines, thus masking aluminium adjuvant’s potentially harmful effect” and that a previous study had found worse seroprotection following aluminum-adjuvanted H5N1 vaccines, the study authors wanted to know: what, generally speaking, are the effects of ACVs vs. placebo?  (See link for article)

Study here:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226993/

Simply put: aluminum adjuvants don’t work.

Yet another example of ZERO benefits but increased risks.

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635311/

Adjuvant-dependent effects on the safety and efficacy of inactivated SARS-CoV-2 vaccines during heterologous infection by a SARS-related coronavirus

Mark Heise, Jacob Dillard, Sharon Taft-Benz, Audrey Knight, Elizabeth Anderson, Katia Pressey, Breantié Parotti, Sabian Martinez, Jennifer Diaz, Sanjay Sarkar, Emily Madden, Gabriela De la Cruz, Lily Adams, Kenneth Dinnon, III, Sarah Leist, David Martinez, Alexandra Schaefer, John Powers, Boyd Yount, Izabella Castillo, Noah Morales, Jane Burdick, Mia Katrina Evangelista, Lauren Ralph, Nicholas Pankow, Colton Linnertz, Prem Lakshmanane, Stephanie Montgomery, Martin Ferris, Ralph Baric, and Victoria Baxter

Abstract

Inactivated whole virus SARS-CoV-2 vaccines adjuvanted with aluminum hydroxide (Alum) are among the most widely used COVID-19 vaccines globally and have been critical to the COVID-19 pandemic response. Although these vaccines are protective against homologous virus infection in healthy recipients, the emergence of novel SARS-CoV-2 variants and the presence of large zoonotic reservoirs provide significant opportunities for vaccine breakthrough, which raises the risk of adverse outcomes including vaccine-associated enhanced respiratory disease (VAERD). To evaluate this possibility, we tested the performance of an inactivated SARS-CoV-2 vaccine (iCoV2) in combination with Alum against either homologous or heterologous coronavirus challenge in a mouse model of coronavirus-induced pulmonary disease. Consistent with human results, iCoV2 + Alum protected against homologous challenge. However, challenge with a heterologous SARS-related coronavirus, Rs-SHC014-CoV (SHC014), up to at least 10 months post-vaccination, resulted in VAERD in iCoV2 + Alum-vaccinated animals, characterized by pulmonary eosinophilic infiltrates, enhanced pulmonary pathology, delayed viral clearance, and decreased pulmonary function. In contrast, vaccination with iCoV2 in combination with an alternative adjuvant (RIBI) did not induce VAERD and promoted enhanced SHC014 clearance. Further characterization of iCoV2 + Alum-induced immunity suggested that CD4+ T cells were a major driver of VAERD, and these responses were partially reversed by re-boosting with recombinant Spike protein + RIBI adjuvant. These results highlight potential risks associated with vaccine breakthrough in recipients of Alum-adjuvanted inactivated vaccines and provide important insights into factors affecting both the safety and efficacy of coronavirus vaccines in the face of heterologous virus infections.

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**Comment**

According to this:

Ribi adjuvants are emulsions of salt water, a detergent, two bacterial products and the approved adjuvant squalene. Ribi interacts with immune cells to enhance the release of cytokines (immune molecules) and antigen processing.

The article gives three examples of VAERD known about since the 1960s:

  • large numbers of breakthrough pediatric measles cases occurred years after vaccination that were “atypical” in that the children had all measles symptoms, including rash, but the measles virus could not be isolated from them.

  • infants who received the respiratory syncytial virus (RSV) vaccine were later infected by RSV and developed VAERD.

  • severe dengue disease outbreaks in dengue-vaccinated children who had previously taken a dengue vaccine.

COVID-19 vaccination-induced VAEDS was already recognized as a complication by the summer of 2020, while the “vaccines” were still under evaluation.

Aluminum, the main ingredient in alum, is associated with many ill effects including injection site inflammation, endocrine disruption, and damage to the digested, cardiovascular and pulmonary systems.  Clinical and immunologic similarities between vaccine-induced illness in mice and VAERD in people both involve type 2 inflammation and the infiltration of immune system cells into the lungs.

A 2021 study on the aluminum content of 13 common childhood vaccines  found that only three contained quantities of alum indicated by the manufacturer. Six had (statistically) significantly more alum and four had less.

A 2019 investigative report detailed how the U.S. government concealed expert witness testimony that vaccines can and do indeed cause autism in some children.

The CDC website currently makes no mention of the expert testimony, published findings or similar studies, or numerous cases in which the government has paid damages in vaccine court to children who — according to the vaccine court and medical experts — got autism as a result of their vaccine injuries. The CDC states unequivocally that “vaccines do not cause autism.”

Another version of “safe and effective,” and “persistent Lyme doesn’t exist.”

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