Cancer Metabolism as a Therapeutic Target and Review of Interventions

October 5, 2023

https://www.mdpi.com/2072-6643/15/19/4245

Cancer Metabolism as a Therapeutic Target and Review of Interventions

by 1,2, 3,4,5 and 6,*
*Author to whom correspondence should be addressed.
Nutrients 2023, 15(19), 4245; https://doi.org/10.3390/nu15194245
Received: 28 August 2023 / Revised: 20 September 2023 / Accepted: 26 September 2023 / Published: 1 October 2023
(This article belongs to the Special Issue Editorial Board Members’ Collection Series: Dietary Patterns and Cancer)

Abstract

Cancer is amenable to low-cost treatments, given that it has a significant metabolic component, which can be affected through diet and lifestyle change at minimal cost. The Warburg hypothesis states that cancer cells have an altered cell metabolism towards anaerobic glycolysis. Given this metabolic reprogramming in cancer cells, it is possible to target cancers metabolically by depriving them of glucose. In addition to dietary and lifestyle modifications which work on tumors metabolically, there are a panoply of nutritional supplements and repurposed drugs associated with cancer prevention and better treatment outcomes. These interventions and their evidentiary basis are covered in the latter half of this review to guide future cancer treatment.
nutrients-15-04245  pdf of the study
(See link for article)
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SUMMARY:
  1. Glucose management: low carb, high fat, ketogenic diet
  2. Modified time restricted eating
  3. Exercise: aerobic and resistance training, stress reduction/sleep
  4. 20,000-50,000 IU D3 daily
  5. 1mg and increase to 20-30mg at night extended/slow release
  6. Green tea catechins – 500-100mg daily
  7. Metformin 1,000mg 2X/day
  8. Curcumin 600mg daily
  9. Mebendazole 100-200mg daily
  10. Omega 3 fatty acids 2-4g/day
  11. Berberine 100-1500mg or 500-600mg 2-3X/day
  12. Atorvastatin 40mg 2X/day
  13. Disulfiram 80mg 3Xday or 500mg once a day
  14. Cimetidine 400-800 mg 2X/day
  15. Mistletoe given SubQ by doctor
  16. Ashwaganda 2g/day during chemotherapy
  17. Sildenafil 20mg/day
  18. Itraconazoe 400-600mg/day

There is now a spate of cancer following the rollout of the COVID shots.  Lyme/MSIDS patients are already at a higher cancer risk.  Talk about these interventions with your doctor.

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Category:

Activism, Cancer, research, Supplements, Treatment

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