Autoimmune Inflammatory Reactions in Terminally Differentiated Tissues & Inability to Work Following COVID Shots – A Relevant Aspect For Future Boosters

September 20, 2023

https://www.researchgate.net/publication/373925710_Autoimmune_inflammatory_reactions_triggered_by_the_COVID19_genetic_vaccines_

Autoimmune inflammatory reactions triggered by the COVID-19 genetic vaccines in terminally differentiated tissues Autoimmune inflammatory reactions triggered by the COVID-19 genetic vaccines in terminally differentiated tissues

September 2023

DOI:10.1080/08916934.2023.2259123
Authors: Panagis Polykretis, Alberto Donzelli,Azienda Sanitaria Locale di Milano, Janci C Lindsay, David M Wiseman

Abstract

As a result of the spread of SARS-CoV-2, a global pandemic was declared. Indiscriminate COVID-19 vaccination has been extended to include age groups and naturally immune people with minimal danger of suffering serious complications due to COVID-19. Solid immuno-histopathological evidence demonstrates that the COVID-19 genetic vaccines can display a wide distribution within the body, affecting tissues that are terminally differentiated and far away from the injection site. These include the heart and brain, which may incur in situ production of spike protein eliciting a strong autoimmunological inflammatory response. Due to the fact that every human cell which synthesises non-self antigens, inevitably becomes the target of the immune system, and since the human body is not a strictly compartmentalised system, accurate pharmacokinetic and pharmacodynamic studies are needed in order to determine precisely which tissues can be harmed. Therefore, our article aims to draw the attention of the scientific and regulatory communities to the critical need for biodistribution studies for the genetic vaccines against COVID-19, as well as for rational harm-benefit assessments by age group.
Numerous studies report the onset of autoimmune reactions following COVID-19 vaccination [47, 59-76]. The histopathological data provide indisputable evidence that demonstrates that the genetic vaccines exhimbit an off-target distribution, causing the synthesis of the spike protein and thus triggering autoimmune inflammatory reactions, even in tissues which are terminally differentiated and subject to symptomatic damage [38-40, 42].
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The conclusions are inescapable, mRNA vaccines will cause autoimmunity in all applications. The human body is simply too good at recognizing foreign proteins that populate at the cell surface synthesized from mRNA on ribosomes in the Golgi complex. ~ Dr. Peter McCullough

https://pubmed.ncbi.nlm.nih.gov/37562083/

Inability to work following COVID-19 vaccination-a relevant aspect for future booster vaccinations

J Reusch 1, I Wagenhäuser 1, A Gabel 2, A Höhn 2, T-T Lâm 3, L B Krone 4, A Frey 5, A Schubert-Unkmeir 3, L Dölken 6, S Frantz 5, O Kurzai 7, U Vogel 8, M Krone 8, N Petri 9

PMID: 37562083

DOI: 10.1016/j.puhe.2023.07.008

Abstract

Objectives: COVID-19 vaccination is a key prevention strategy to reduce the spread and severity of SARS-CoV-2 infections. However, vaccine-related inability to work among healthcare workers (HCWs) could overstrain healthcare systems.

Study design: The study presented was conducted as part of the prospective CoVacSer cohort study.

Methods: This study examined sick leave and intake of pro re nata medication after the first, second, and third COVID-19 vaccination in HCWs. Data were collected by using an electronic questionnaire.

Results: Among 1704 HCWs enrolled, 595 (34.9%) HCWs were on sick leave following at least one COVID-19 vaccination, leading to a total number of 1550 sick days. Both the absolute sick days and the rate of HCWs on sick leave significantly increased with each subsequent vaccination. Comparing BNT162b2mRNA and mRNA-1273, the difference in sick leave was not significant after the second dose, but mRNA-1273 induced a significantly longer and more frequent sick leave after the third.

Conclusion: In the light of further COVID-19 infection waves and booster vaccinations, there is a risk of additional staff shortages due to post vaccination inability to work, which could negatively impact the already strained healthcare system and jeopardize patient care. These findings will aid further vaccination campaigns to minimize the impact of staff absences on the healthcare system.

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Activism, research, vaccines, Viruses

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