https://oem.bmj.com/content/74/7/502

Occupational exposure to pesticides and other biocides and risk of thyroid cancer

Fanhua Zeng1,2Catherine Lerro2Jérôme Lavoué3Huang Huang4Jack Siemiatycki3Nan Zhao2Shuangge Ma5Nicole C Deziel2Melissa C Friesen6Robert Udelsman7Yawei Zhang2,4

Abstract

Objectives To assess the associations between occupational exposure to biocides and pesticides and risk of thyroid cancer.

Methods Using data from a population-based case–control study involving 462 incident thyroid cancer cases and 498 controls in Connecticut collected in 2010–2011, we examined the association with occupational exposure to biocides and pesticides through a job-exposure matrix. We used unconditional logistic regression models to estimate OR and 95% CI, adjusting for potential confounders.

Results Individuals who were occupationally ever exposed to biocides had an increased risk of thyroid cancer (OR=1.65, 95% CI 1.16 to 2.35), and the highest risk was observed for the high cumulative probability of exposure (OR=2.18, 95% CI 1.28 to 3.73). The observed associations were similar when we restricted to papillary thyroid cancer and well-differentiated thyroid cancer. Stronger associations were observed for thyroid microcarcinomas (tumour size ≤1 cm). No significant association was observed for occupational exposure to pesticides.

Conclusions Our study provides the first evidence linking occupational exposure to biocides and risk of thyroid cancer. The results warrant further investigation.

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**Comment**
Biocides are disinfectants, antiseptics, and preservatives.  For the 23 different types, see:  https://copublications.greenfacts.org/en/biocides-antibiotic-resistance/figtableboxes/12.htm
Of particular concern are human hygiene products, in-can preservatives, insecticides (acaricides – arthropod control), repellents, and food preservatives.
Regarding insecticides/acaricides, always cover your body when spraying, wear gloves, and stand so that the sprays do not come back on you.  Avoid breathing sprays into lungs.