Diagnostics 2019, 9(1), 25;

Disseminated Bartonella henselae Infection Visualized by [18F]FDG-PET/CT and MRI

Published: 1 March 2019
We describe the clinical course of a 24-year old male with Crohn’s disease in immunosuppressive therapy admitted with a 6-week history of fever, weight loss, night sweat, and general malaise. The patient received extensive workup for a fever of unknown origin and received empiric antibiotics. Workup with Fluorine-18 fluoro-2-deoxy-d-glucose ([18F]FDG) positron-emission tomography (PET/CT), and magnetic resonance imaging (MRI) with intravenous contrast showed multifocal ostitis of the columna and os sacrum, as well as abscesses in m. iliopsoas and m. iliacus and affection of the retroperitoneum, liver, and spleen. Initially, malignancy was suspected, but a subsequent liver biopsy showed necrotizing granulomatous inflammation and a later polymerase chain reaction (PCR) showed Bartonella henselae. The patient had relevant exposure from housecats. He was treated with Doxycycline and Rifampicin for 12 weeks resulting in complete recovery. This case is, to our knowledge, a rare example of disseminated infection with Bartonella henselae visualized on both [18F]FDG-PET/CT and MRI. View Full-Text
The Cat’s beginning to get out of the bag regarding Bartonella.  Prepare yourself to see a whole lot more of this. I’m thankful that the authors stated that this case was to their knowledge a rare example; however, Bartonella has flown under the radar for so long chances are quite high there is much more of this going on. Similarly to Lyme and other coinfections, testing that relies on serology is abysmal and many remain undiagnosed.
We’ve always been told that folks that contract Bartonella need a history of cat exposure or other animals and have suppressed immune systems.  Please know, many completely healthy individuals with NO cat exposure can have disseminated Bartonella.  For examples of this:  After the study I list 6 cases.
Dr. Ericson’s work has shown Bartonella virtually everywhere in the human body:  Slides in link
In my experience Bartonella is as bad if not worse than Lyme which gets all the press. Authorities do not even consider it with Lyme patients but nearly everyone I work with has it along with Lyme and often Babesia as well as Mycoplasma and various viruses.  Until the polymicrobial aspect is acknowledged and treated, we are doomed as patients.
Yes, Martha, Lone Star ticks are in Wisconsin as well: