3rd letter to ADM Brett P. Giroir, M.D., Assistant Secretary for Health

Carl Tuttle
Hudson, NH, United States
DEC 9, 2018 —

How much evidence do we need that this 21st Century incurable plague has been horribly mishandled for three decades at the expense of the disabled Lyme community?
Write your own letter of concern to the Assistant Secretary for Health as I have yet to receive a response. I spoke with a legislative assistant last Thursday in reference to obtaining a response from Dr. Brett P. Giroir and we talked about a congressional investigation with subpoena power.

Letter to: ADM Brett P. Giroir, M.D., Assistant Secretary for Health
—— Original Message ———-
From: Carl Tuttle <>
To:, Alex.Azar@HHS.GOV,
Cc: (64 Undisclosed recipients)
Date: December 9, 2018 at 10:03 AM

Subject: Re: CDC Track Record for Lyme Disease
Dec 9, 2028
U.S. Department of Health & Human Services
200 Independence Avenue, S.W.
Washington, D.C. 20201

Attn: ADM Brett P. Giroir, M.D., Assistant Secretary for Health

Dear Dr. Giroir,
I would like to call attention to the following study recently published in Diagnostic Microbiology and Infectious Disease:
Diagn Microbiol Infect Dis. 2018 Nov;92(3):183-188. doi: 10.1016/j.diagmicrobio.2018.06.007. Epub 2018 Jun 18.

Critical analysis of a doxycycline treatment trial of rhesus macaques infected with Borrelia burgdorferi.
Wormser GP1, O’Connell S2, Pachner AR3, Schwartz I4, Shapiro ED5, Stanek G6, Strle F7.
A critical analysis was conducted of a doxycycline treatment trial of Indian rhesus macaques. In this treatment trial, the investigators attempted to infect the primates with Borrelia burgdorferi sensu stricto by at least 10 tick bites from artificially infected ticks. None of the primates became ill; nevertheless, 5 primates were treated with a 28-day course of oral doxycycline. In contrast to the conclusions of the authors, the data did not convincingly document the existence of viable B. burgdorferi in antibiotic-treated primates. The investigators were unable to cultivate the spirochete from any animal after treatment using highly sensitive in vitro methods. Like many prior animal studies, the current study also did not document that the doxycycline exposure in these animals was similar to that expected in humans. Numerous additional methodologic problems are discussed.
Borrelia burgdorferi; Doxycycline; Lyme disease; Persistence; Treatment

What is the purpose of this publication (other than to add more confusion/distraction) which doesn’t offer any advancements in the treatment of Lyme disease.

I believe these individuals are attempting to preserve their 30-year racketeering scheme that Lyme is “difficult to catch and easily treated.” (Wormser/Shapiro are defendants in the Texas RICO lawsuit)

Just plain junk science as usual….. If there was no infection in the first place, why would they expect to find viable B. burgdorferi after antibiotic treatment??

Once again, this study was NIH funded with US taxpayer dollars.

Two quotes from Willy Burgdorfer: (discoverer of Lyme disease spirochete)

  1. “The Lyme disease spirochete is far more virulent than Treponema pallidum. (Syphilis)”
  2. The controversy in Lyme disease research is a shameful affair. I say that because the whole thing is politically tainted. Money goes to people that have for the past thirty years produced the same thing. Nothing.”
    Source: (Live interview)
    Prof. Willy Burgdorfer Talks About Lyme Disease

Note: Embers et al produced a definitive demonstration of postantibiotic treatment persistence of Bb in nonhuman primates. [1]

Dr. Giroir,

I am attaching the following four documents for your review:

  1. Persistence of Lyme Disease (273 references)
    Compiled by: John D. Scott, Research Division, Lyme Disease Association of Ontario April 2013
  2. Peer Reviewed Evidence of Persistence of Lyme Disease Spirochete Borrelia burgdorferi and Tick-Borne Diseases (700 references)
  3. Congenital Transmission of Lyme 2015
    Dr. Eugene Shapiro has been identified as a physician who routinely spreads disinformation about Lyme disease as found in the following 2014 NEJM article:
    “Lyme Disease” Excerpt:  “I would reassure her that the outcomes of treatment are excellent and that congenital Lyme disease has never been documented.” -Eugene D. Shapiro, M.D.  You can find a documented list of Shapiro’s misleading quotes here:  Memorable quotes from Dr Shapiro
  4. Seronegativity in Lyme borreliosis and Other Spirochetal Infections 16 September 2003  “If false results are to be feared, it is the false negative result which holds the greatest peril for the patient.” –Alan McDonald, Pathologist


Once again I ask the question Dr. Giroir; is the mishandling of Lyme disease a result of incompetence or collusion?

Will you continue to ignore the evidence that a handful of academics aligned with the U.S. Centers for Disease Control have stifled the necessary research to find a curative approach for this antibiotic resistant/tolerant superbug?…. thirty years and counting.

When you finally respond to my emails please hit “Reply-All” as copies have been sent to legislators who are listening to public outcry.
-Carl Tuttle
Lyme Endemic Hudson, NH

[1] Embers ME, Barthold SW, Borda JT, et al. Persistence of Borrelia burgdorferi in rhesus macaques following antibiotic treatment of disseminated infection. PLoS One. 2012;7(1):e29914.
[2]Memorable and Not So Memorable Quotes by Lyme Disease Denialists  In Copyright Since September 11, 2000.  This web site is in no manner affiliated with any Kaiser entity and the for profit Permanente Permission is granted to mirror this web site – Please acknowledge where the material was