Archive for February, 2018

Understanding Q Fever Risk to Minnesotans

http://online.liebertpub.com/doi/10.1089/vbz.2017.2132

Understanding Q Fever Risk to Humans in Minnesota Through the Analysis of Spatiotemporal Trends

Alvarez Julio, Whitten Tory, Branscum Adam J., Garcia-Seco Teresa, Bender Jeff B., Scheftel Joni, and Perez Andres. Vector-Borne and Zoonotic Diseases. February 2018, 18(2): 89-95.  Published in Volume: 18 Issue 2: February 1, 2018

Understanding Q Fever Risk to Humans in Minnesota Through the Analysis of Spatiotemporal Trends

ABSTRACT
Q fever is a widely distributed, yet, neglected zoonotic disease, for which domestic ruminants are considered the main reservoirs in some countries. There are still many gaps in our knowledge of its epidemiology, and the source of sporadic cases is often not determined. In this study, we show how Q fever surveillance data in combination with information routinely collected by government agencies in Minnesota during 1997 to 2015 can be used to characterize patterns of occurrence of Q fever illnesses and detect variables potentially associated with increased human illness. Cluster analysis and Bayesian spatial regression modeling revealed the presence of areas in Southern Minnesota at higher risk of Q fever. The number of sheep flocks at the county level helped to explain the observed number of human cases, while no association with the cattle or goat population was observed. Our results provide information about the heterogeneous spatial distribution of risk of Q fever in Minnesota.

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1280px-Coxiella_burnetii_01Image credit: en:Rocky Mountain Laboratories, NIAID, NIH

**Comment**

The causative agent of Q Fever, Coxiella burnetii, is a small Gram-negative bacterium morphologically similar to Rickettsia, but with genetic and physiological differences.  It has been isolated from approximately 40 species of ticks with possible tick borne transmission reported.  The most common mode of transmission is inhalation of infectious aerosols from fluids of infected animals.  It can become airborne and travel for miles causing outbreaks.  Person to person transmission is possible as well. It can survive standard disinfectants, and is resistant to many other environmental changes like those presented in the phagolysosome.  The CDC reports that 60% of cases are in patients without livestock contact (CDC unpublished data, 2010) and the need for health-care professionals to consider Q fever in the differential diagnosis in patients with a compatible illness, even in the absence of occupational risk or history of direct contact with animal reservoirs.

Supposedly, he United States ended its biological warfare program in 1969. When it did, C. burnetii was one of seven agents it had standardized as biological weapons.  https://en.wikipedia.org/wiki/Coxiella_burnetii

Q Fever can cause acute or chronic illness.

https://www.medscape.com/viewarticle/803800
Excellent video by Alicia Anderson, DVM, MPH on new CDC guidelines for Q Fever

Excerpts below:

https://www.cdc.gov/mmwr/preview/mmwrhtml/rr6203a1.htm

Summary of Acute Q Fever
Prolonged fever (>10 days) with a normal leukocyte count, thrombocytopenia, and increased liver enzymes is suggestive of acute Q fever infection.
Children with Q fever generally have a milder acute illness than adults.
Children are more likely to have a rash than adults. Rash has been reported in up to 50% of children with acute Q fever.
Women infected with Q fever during pregnancy are at increased risk for miscarriage and preterm delivery.
Women of child-bearing age who receive a diagnosis of Q fever can benefit from pregnancy screening and counseling to guide health-care management decisions

Treatment: Symptomatic patients with confirmed or suspected acute Q fever, including children with severe infections, should be treated with doxycycline, which is most effective if given within the first 3 days of symptoms.  Other antibiotic regimens that can be used if doxycycline is contraindicated because of allergies include moxifloxacin, clarithromycin, trimethoprim/sulfamethoxazole, and rifampin.  Patients with acute Q fever should undergo a careful clinical assessment to determine whether they might be at risk for progression to chronic Q fever because patients at high risk require closer observation during the convalescent period.

Summary of Chronic Q Fever
Persons who are at high risk for development of chronic Q fever include persons with preexisting valvular heart disease, vascular grafts, or arterial aneurysms.
Infection during pregnancy and immunosuppression (e.g., from chemotherapy) are both conditions that have been linked to chronic Q fever development.
Endocarditis and infections of aneurysms or vascular prostheses are the most common forms of chronic Q fever and generally are fatal if untreated.
Chronic Q fever is rarely reported in children.
In contrast with adults, osteomyelitis is one of the most common findings in children with pediatric chronic Q fever.

Treatment:  Adults who receive a diagnosis of chronic Q fever should receive a treatment regimen of doxycycline and hydroxychloroquine (100 mg of doxycycline twice daily with 200 mg of hydroxychloroquine three times daily); duration of treatment might vary by the site of infection. A combination regimen is necessary to eradicate the organism because hydroxychloroquine raises the pH in the acidified phagosomal compartment and, in combination with doxycycline, has been shown to have in vitro bactericidal activity against C. burnetii. Because of potential retinal toxicity from long-term use of hydroxychloroquine, a baseline ophthalmic examination should be performed before treatment and every 6 months thereafter. Both doxycycline and hydroxychloroquine can cause photohypersensitivity, and hypersensitivity to sunlight is a potential complication with acute and chronic treatment regimens. Hydroxychloroquine is contraindicated in persons with glucose-6-phosphate dehydrogenase deficiency and persons with retinal or visual field deficits.

During treatment for chronic Q fever, patients should receive monthly serologic testing for C. burnetii phase I and II IgG and IgM antibodies and monthly clinical evaluations. If an appropriate treatment response is not achieved, monthly monitoring for hydroxychloroquine plasma levels (which should be maintained at 0.8–1.2 µg/mL) and doxycycline plasma levels (which should be maintained at ≥5 µg/mL) should also be performed during the treatment (145,146). Treatment should continue for at least 18 months for native valve infections and at least 24 months for prosthetic valve infections.

Rather than rely on indiscriminate application of predetermined cutoff titers, health-care providers should use serologic testing as a tool to ensure that the phase I IgG is decreasing during treatment in conjunction with recovery from clinical symptoms. A patient who has been treated appropriately for ≥18 months and has recovered from clinical symptoms but whose phase I IgG remains ≥1:1024 might not benefit from continued treatment.

See CDC link for treatment for pregnant women and children.

Q Fever is a notifiable disease in the U.S.

 

 

 

Do These Popular Diets Make You Nutrient Deficient?

https://vitalplan.com/blog/is-your-diet-making-you-nutrient-deficient?

EmptyPlate (1)

Do These Popular Diets Make You Nutrient Deficient?

by Carin Gorrell | Posted February 2nd, 2018

Eating well and meeting all of the daily nutritional recommendations is hard enough when you have no dietary restrictions. But if you’re on any kind of diet that eliminates specific ingredients or entire categories of foods—whether it’s for health purposes, to lose weight, to align with your ethical beliefs, or any other reason—there’s a good chance you’re falling short on certain key nutrients, says nutrition counselor Stephanie Clarke, M.S., R.D., cofounder of C&J Nutrition.

That doesn’t mean, however, that you have to break your diet rules in order to meet your nutritional needs. Which is especially reassuring news if you’re someone with a serious condition like Celiac disease who simply can’t start eating whole grains without some very real health consequences.

We asked Clarke to help identify possible deficiencies you should be thinking about if you’re following a Paleo, Keto, gluten-free, strict elimination, or vegan diet. Keep reading to discover the most common deficiencies, plus what you can add to your plate that’s within your dietary restrictions to help replace those missing nutrients.

The Paleo Diet

The basic premise of the Paleo Diet is that you can eat anything a caveman (or cavewoman) could hunt or gather back in the Paleolithic era, more than 2 million years ago. That means yes to meat, fish, nuts, leafy greens, regional produce, and seeds, and no to modern foods—namely grains, dairy, and legumes.

You might be missing: Calcium, folate, and fiber

Smart fixes: It’s hard to get enough calcium from natural sources other than dairy, so Clarke suggests looking for a Paleo-friendly non-dairy milk like coconut or almond milk that’s fortified with calcium. If you’re eating plenty of vegetables, you’re likely getting enough fiber and folate, a B vitamin that’s essential for heart health, preventing birth defects, and more. But if your diet is pretty meat heavy, start piling more vegetables like broccoli, asparagus, and dark leafy greens on your plate.

The Keto Diet

This diet was originally developed for use in hospitals to help control seizures in children with epilepsy, says Clarke, but has recently become popular for weight loss. The very low-carb, high-fat plan requires you get only 10% of your calories from carbohydrates and 20% from protein; the remaining 70% should come from fat—think tons of meat, fish, nuts, and oils. Even fruits and vegetables are limited because of their carbohydrates, and so is dairy thanks to its lactose (a natural sugar).

You might be missing: Fiber, B vitamins, vitamins A and C, and calcium

Smart fixes: Eat more green leafy vegetables like spinach, chard, and kale, which are low in carbs but high in B vitamins, A, C, and fiber. These greens also contain some calcium, but not enough, so Clarke recommends taking a daily multivitamin and mineral supplement that includes 100% of your daily value of key vitamins and minerals.

Gluten-Free Diet

Only a small percentage of people have Celiac or a true intolerance to gluten, a protein in wheat (and wheat varieties and derivatives like farro and spelt), rye, barley, triticale, malt, brewer’s yeast, and wheat starch. But many more people have a sensitivity to gluten, and nixing it from their diet can relieve symptoms such as GI distress, brain fog, and joint pain.

You might be missing: Folate and fiber

Smart fixes: Falling short on B vitamins and fiber is really only a concern if you don’t eat a lot of vegetables and you’re entirely grain-free (meaning you don’t eat gluten-free grains like brown rice, quinoa, and amaranth), explains Clarke. If that’s you, time to load up on leafy greens for folate, and beans and produce like raspberries, apples, and pears for fiber. Note that many gluten-free packaged products such as breads and cereals are not fortified with folic acid (the synthetic version of folate), so don’t count on those to meet your folate needs unless the label says otherwise.

Elimination Diet

These diets can vary depending on your individual needs, but it involves eliminating all foods that are suspected of disrupting digestive function and health due to allergies, sensitivities, chronic illness, or an otherwise impaired immune system. That can entail nixing all grains (there may be some exceptions, such as white rice), seeds, dairy, eggs, legumes, tree nuts, nightshade and cruciferous vegetables, and most meat (aside from chicken and fish).

You might be missing: Calcium, folate, vitamin D, omega-3 fatty acids, fiber, and enough calories in general

Smart fixes: Remember that most non-dairy milks are fortified with calcium, so choose one that is (check the label) and that works with your plan, such as oat or rice milk. Your folate is likely low because you’re not eating fortified foods or some of the top vegetable sources such as black-eyed peas (legumes) and broccoli (cruciferous), so focus on the high-folate produce you can have such as asparagus, white rice, and avocado. Look to vegetables and fruits on your “yes” list to help pump up your fiber intake as well.

Vegan Diet

Veganism is characterized by no animal products, including all meat, fish, eggs, and dairy. It’s a rapidly growing trend: While only about 6% of Americans are vegan according to one 2017 survey, that’s exponentially higher than the estimated 1% of vegans in 2014.

You might be missing: B12, iron, and protein

Smart fixes: The only reliable vegan source of B12 is fortified foods (non-dairy milks and some tofu, soy, and cereal products), so if you’re not eating fortified foods a few times a day, you should take a B12 supplement, says Clarke.

Iron from non-heme (non-animal) sources is not as easily absorbed by the body. It’s easy to get enough from sources like legumes, blackstrap molasses, nuts, seeds, dried fruits, whole grains, and even dark chocolate, just be sure to pair it with a little vitamin C (strawberries, kiwi, oranges), which aids in iron absorption, says Clarke.

When it comes to protein, most Americans (including vegans) get more than they need, which is 10-20% of their daily calories, says Clarke. But if you suspect you’re falling short, aim to have two or more complementary proteins at every meal—pairing incomplete proteins such as whole wheat, rice, beans, lentils, and peanuts will provide all the essential amino acids you need.

As for vitamin D and omega-3s, two 3-4 ounce servings of salmon a week should be enough to hit your levels, but you might still consider taking a vitamin D supplement—even the healthiest people have trouble getting enough D, says Clarke. And if you’re struggling to meet your caloric needs, lean on high-fat avocado and oils on your approved list (avocado, canola, grapeseed, and olive oils are usually allowed): One gram of fat delivers 9 calories, compared to only 4 calories in a gram of carbohydrate or protein.


As always, talk with your healthcare practitioner if you have any concerns about nutritional deficiencies or starting a new diet or supplement. Have other questions or suggestions about filling in nutritional gaps? Share them with us on Facebook.

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**Comment**

Food is important for everyone, but the Lyme/MSIDS patient needs to take it extremely seriously.  This article points out some possible holes in various diets.  Please work with a good nutritionist and figure out your personal imbalances.  It will help you greatly in your journey.

For more:  https://madisonarealymesupportgroup.com/2017/11/24/feel-helplessly-predestined-for-disease-listen-to-this/  Cyndi O’Meara is a nutritionist, film maker – ‘What’s With Wheat?’, best-selling author, international speaker and founder of Changing Habits.  She gives simple and practical steps to change your health.

https://madisonarealymesupportgroup.com/2017/05/20/minding-your-mitochondria/  Diagnosed with MS, Dr. Terry Wahls received the best standard medicine had to offer. After declining to the point of being in a wheel chair, she took matters into her own hands and learned how to properly fuel her body. Using the lessons she learned at the subcellular level, she used diet to cure her MS and get out of her wheelchair.

https://madisonarealymesupportgroup.com/2018/02/02/leaky-gut-free-guide/

https://madisonarealymesupportgroup.com/2018/01/03/the-invisible-universe-of-the-human-microbiome-msm/  Great video explaining how 70-80% of our immune system is in our gut and the importance of eliminating sugar.  I add info about how MSM, a safe, inexpensive supplement can help heal leaky gut.

https://madisonarealymesupportgroup.com/2016/05/25/nutritional-video/  Excellent video that explains many nutritional myths we’ve grown up with including – fat is bad. It also points out a few things that are helpful for weight loss, since many MSIDS patients gain weight while in treatment. It also discusses digestive enzymes with ingredients I cover in the article about systemic enzymes: https://madisonarealymesupportgroup.wordpress.com/2016/04/22/systemic-enzymes/

 

Upcoming SIBO Webinar

SIBO – The Silent Driver of Neuro-inflammation, Anxiety and Pain

with Dr. Brett Wisniewski, Bs, D.C., DACBN, DABCI

Thursday February 8th at 10 AM PST
Can’t be there live? No worries, when you register you will be sent a link to the recording.
CLICK HERE to REGISTER:  https://mpamedia.webex.com/mw3200/mywebex/default.do?nomenu=true&siteurl=mpamedia&service=6&rnd=0.9108669679642906&main_url=https%3A%2F%2Fmpamedia.webex.com%2Fec3200%2Feventcenter%2Fevent%2FeventAction.do%3FtheAction%3Ddetail%26%26%26EMK%3D4832534b00000004b50ca6a53a98c614c571e162e3f4fafbf6164857bcbd979fa703d9850ed84520%26siteurl%3Dmpamedia%26confViewID%3D83882475460263138%26SourceId%3D111%26encryptTicket%3DSDJTSwAAAASHnBEUt5p3G9I7owmWiL2YfBrmzwZC7A6WptOGLU13xg2%26

Topics will Include

  • Relationship of GI Dysbiosis to Mental Health
  • The Role of Biofilms and LPS in Systemic
  • Inflammation
  • Endotoxins and Pain
  • Using Botanical Medicine in SIBO
  • Nutritional Supplementation and Diet for
  • SIBO

Need Help with Protocols?

Biocidin.com

For additional information, please contact Carla Rubie at carla@mpamedia.com

 

 

 

 

 

PDF of Dr. Sue Massie’s Webinar on Lyme/MSIDS

https://madisonarealymesupportgroup.com/2017/11/16/free-webinar-on-lyme-dr-sue-massie/ and https://madisonarealymesupportgroup.com/2017/11/30/dr-sue-massie-lyme-webinar/

Back in November, I posed info for a webinar by Dr. Sue Massie, also infected, on Lyme/MSIDS (in above link).  It was excellent and about an hour and a half long with helpful information.  I just stumbled upon her pdf that accompanies the webinar:  https://tdinj.com/wp-content/uploads/2017/12/Sue-Massie-Lyme-The-Great-Imitator.pdf

Leaky Gut – Free Guide

https://info.dralexrinehart.com/articles/understanding-leaky-gut-autoimmunity-and-beyond?

by Dr. Alex Rinehart

Understanding Leaky Gut, Autoimmunity, and Beyond

leaky gut.jpg

Leaky gut is when the intestines absorb bacteria, toxins, and undigested food into the bloodstream.

Once in the bloodstream, these materials trigger inflammation and abnormal immune responses.

Leaky gut has been linked to a number of health problems like Crohn’s disease, irritable bowel syndrome, depression, chronic fatigue syndrome, and virtually every autoimmune disease.

If you suffer with any of those conditions, a good treatment plan must address leaky gut.

Pioneering researcher and medical doctor Dr. Alessio Fasano published a landmark paper in 2012 detailing the the integral link between leaky gut and autoimmune disease.

The paper boldly suggests that autoimmune disease cannot exist without leaky gut.

Normally, a primary job of the intestines is to block the absorption of larger material. It becomes “leaky” by absorbing bigger proteins than it should allow in the blood.

Once in the bloodstream, these materials invite immune reactions. Along the way, the body starts mistaking healthy tissues as enemies too.

This “autoimmunity” can target any tissue in the body.

  • The thyroid? Hashimoto’s or Graves’ thyroiditis.
  • The joints? Rheumatoid arthritis.
  • The gut? Celiac disease or Ulcerative colitis.
  • The pancreas? Type I Diabetes
  • Connective tissue? Scleroderma
  • Red blood cells? Hemolytic anemia

So while autoimmune diseases are characterized by the types of tissues the body is attacking – these attacks start by leaky gut.

This means that an autoimmune thyroid condition is not a thyroid problem. Rheumatoid arthritis is not a joint problem. Autoimmunity to ANY tissue is not a problem with that tissue

Autoimmunity is an IMMUNE problem mediated by GUT HEALTH. To manage autoimmune disease successfully – fix leaky gut.

How to Manage Leaky Gut

Some genetic factors like HLA-DQ2 or HLA-DQ8 can increase your risk for leaky gut; yet, ultimately those who carry leaky gut markers are just more easily triggered by lifestyle factors.

Lifestyle factors for leaky gut include.

  • Stress
  • Food intolerance (wheat, dairy, corn, etc)
  • Sugar
  • Alcohol
  • Drugs (especially NSAIDs and PPIs)
  • Infections (bacterial, yeast, fungal, viral and parasitic).
  • Imbalance of Gut Flora, Small Intestinal Bowel Overgrowth/Small Intestinal Fungal Overgrowth
  • Other triggers like radiation exposure, poor sleep, vitamin and mineral deficiencies, and overexercise.

To heal leaky gut, simply follow the bullets above like a roadmap.

Manage stress, limit alcohol and sugar, eat a diverse, nutrient-dense, and low-allergy diet, sleep selfishly, and protect those friendly microbes in your gut!

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**Comment**

Go to link at beginning of article for your Free Guide:  The 5 Most Overlooked Consequences of a Broken Gut

 

For More:  https://madisonarealymesupportgroup.com/2018/01/03/the-invisible-universe-of-the-human-microbiome-msm/