Letter to the Editor/Petition

Oh, this is good.  Get the popcorn.

https://www.change.org/p/the-us-senate-calling-for-a-congressional-investigation-of-the-cdc-idsa-and-aldf/u/18499865?tk=HQJY_dTAdQhqzqoRTwpPEZ1G2bD9xSdDPNZuEPm2VJk&utm_source=petition_update&utm_medium=email

Letter to the Editor: The American Journal of Medicine

Carl Tuttle
Hudson, NH

NOV 17, 2016 — Per the recent publication in the Journal of The American Medical Association it would appear that Gary Wormser of New York Medical College is suffering from delusions of grandeur.

Nov 14, 2016

Elsevier Inc.
1600 John F. Kennedy Boulevard, Suite 1800
Philadelphia, PA 19103-2899
Attn: Joseph S. Alpert, MD Editor-in-Chief, The American Journal of Medicine

Dear Dr. Alpert

Lyme disease is capable of producing sudden death with no warning signs; [1,2,3] heart damage requiring transplant, [4] paralysis with seizures, [5] and persistent infection after antibiotic treatment [6,7,8,9,10] along with congenital transmission [11] and ability to create wheelchair bound patients. [12]

The last time we recognized a disease with this potential to cause serious harm, (Zika) the CDC wanted 1.8 billion for research. [13]

In contrast, Wormser believes Lyme disease is little more than a nuisance disease (like strep throat) curable with a one-size-fits-all treatment approach and any complaints after treatment are simply the aches and pains of daily living.

Wormser’s escapade in controlling the narrative [14] has been well funded and backed by the CDC.
Wormser has played a pivotal role in the collusion to deny a life-altering infection [15,16,17] which has been misclassified as a simple nuisance disease for over three decades. The focus has been to discredit the severely disabled [18] as opposed to finding a cure for this antibiotic resistant/tolerant superbug. [19,20,21,22]

Now Wormser nominates himself for a Nobel Prize and the The American Journal of Medicine publishes his nonsense?

If you haven’t signed the petition, please read about it and sign here:

https://www.change.org/p/the-us-senate-calling-for-a-congressional-investigation-of-the-cdc-idsa-and-aldf

REFERENCES

1. Cardiac Tropism of Borrelia burgdorferi: An Autopsy Study of Sudden
Cardiac Death Associated with Lyme Carditis. (March 2016)
http://ajp.amjpathol.org/article/S0002-9440(16)00099-7/abstract

Excerpt:

“Fatal Lyme carditis caused by the spirochete Borrelia burgdorferi rarely is identified. Here, we describe the pathologic, immunohistochemical, and molecular findings of five case patients.”

2. CDC Case Study #1: Three Sudden Cardiac Deaths Associated with Lyme Carditis: http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6249a1.htm?s_cid=mm6249a1_w

3. CDC Case Study #2: A case report of a 17-year old male with fatal Lyme carditis
http://www.cardiovascularpathology.com/article/S1054-8807(15)00025-3/abstract?rss=yes

4. Professor Neil Spector: Duke physician uses near-death experience to encourage patient self-advocacy
http://www.dukechronicle.com/articles/2015/05/28/duke-physician-uses-near-death-experience-encourage-patient-self-advocacy#.VYlYnxtViko
Dr Neil Spector from Duke University required a heart transplant after his Lyme disease went undiagnosed for four years.

5. Nashua Mom in the ‘Lyme Light’ on Katie Couric Show
http://patch.com/new-hampshire/nashua/nashua-mom-talks-chronic-lyme-on-katie-couric-show
Fifth-grade teacher Kelly Downing was paralyzed from the neck down and interviewed by Katie Couric.

6. Application of Nanotrap technology for high sensitivity measurement of urinary outer surface protein A carboxyl-terminus domain in early stage Lyme borreliosis.
http://translational-medicine.biomedcentral.com/articles/10.1186/s12967-015-0701-z
41 of 100 patients under surveillance for persistent LB in an endemic area were positive for urinary OspA protein after antibiotic treatment.

7. Culture evidence of Lyme disease in antibiotic treated patients living in the Southeast.
http://danielcameronmd.com/culture-evidence-of-lyme-disease-in-antibiotic-treated-patients-living-in-the-southeast/
Rudenko and colleagues reported culture confirmation of chronic Lyme disease in 24 patients in North Carolina, Florida, and Georgia. All had undergone previous antibiotic treatment.

8. DNA sequencing diagnosis of off-season spirochetemia with low bacterial density in Borrelia burgdorferi and Borrelia miyamotoi infections.
https://www.ncbi.nlm.nih.gov/pubmed/24968274

Faulty/misleading antibody tests landed a sixteen year old male in a psychiatric ward when his lab results did not meet the CDC’s strict criteria for positive results. His Western blot had only four of the required five IgG bands. Subsequent DNA sequencing identified a spirochetemia in this patient’s blood so his psychiatric issues were a result of neurologic Lyme disease misdiagnosed by antiquated/misleading serology. This patient was previously treated with antibiotics.

9. Granulomatous hepatitis associated with chronic Borrelia burgdorferi infection: a case report
http://www.labome.org/research/Granulomatous-hepatitis-associated-with-chronic-Borrelia-burgdorferi-infection-a-case-report.html
The patient had active, systemic Borrelia burgdorferi infection and consequent Lyme hepatitis, despite antibiotic therapy.

10. Scotty Shelton and Persistent Infection in Saginaw MN
https://www.change.org/p/the-us-senate-calling-for-a-congressional-investigation-of-the-cdc-idsa-and-aldf/u/11685820
“Scotty’s brain (cerebral cortex) was positive for Borrelia burgdorferi and Borrelia myamotoi, his testicle is positive for Bb. We are now testing other tissues. Seven years of antibiotics and 3.5 years of natural treatments (along with antibiotics) and he was highly highly positive.”

11. Congenital Transmission of Lyme/TBD
(See attachment-28 references)
DropBox file: https://www.dropbox.com/s/z10em0szgpm8bll/Congenital%20Transmission%20of%20Lyme%202015.doc?dl=0

12. Wheelchair-Bound Girl Calls Blessing By Pope Francis ‘Most Precious Moment Of My Life’http://newyork.cbslocal.com/2015/09/24/pope-francis-blesses-girl-in-wheelchair/
NEW YORK (CBSNewYork) — A 12-year-old girl who has been confined to a wheelchair since being diagnosed with Lyme disease said meeting Pope Francis as he arrived in New York Thursday was “the most precious moment of my life.”

13. $1.8 billion to fight Zika: CDC moves to highest alert level
https://www.washingtonpost.com/news/post-politics/wp/2016/02/08/obama-to-ask-congress-for-1-8-billion-to-combat-zika-virus/

14. Scientific misconduct or criminal offense?
https://www.change.org/p/the-us-senate-calling-for-a-congressional-investigation-of-the-cdc-idsa-and-aldf/u/14006106

Dr Gary Wormser of New York Medical College is using taxpayer dollars to support his career long bias against persistent infection while designing studies excluding the sickest of the patient population focusing on the acute stage of disease after early treatment.
The deceptive results of his study is then assumed to apply to the entire patient population giving the impression that Lyme is a simple nuisance disease and patients who are severely disabled are somehow delusional.

15. Amy Tan: SLyme Disease: How A Speck Changed My Life Forever
http://www.humanthology.com/lyme-disease/2014/9/15/slyme-disease-how-a-speck-changed-my-life-forever

16. Averil Lavine: Avril Lavigne Opens Up About Her Health Crisis: ‘I Was Bedridden for 5 Months’
http://www.people.com/article/avril-lavigne-lyme-disease-bedridden

17. Yolanda Foster: Yolanda Foster on Lyme Disease: I’ve Lost Ability to Read, Write, Watch TV
http://www.usmagazine.com/celebrity-news/news/yolanda-foster-on-lyme-disease-ive-lost-ability-to-read-write-2015191

18. Antiscience and ethical concerns associated with advocacy of Lyme disease
Prof Gary P Wormser, MD coauthor
http://www.thelancet.com/journals/laninf/article/PIIS1473-3099(11)70034-2/abstract?rss=yes

19. A Drug Combination Screen Identifies Drugs Active against Amoxicillin-Induced Round Bodies of In Vitro Borrelia burgdorferi Persisters from an FDA Drug Library
http://journal.frontiersin.org/article/10.3389/fmicb.2016.00743/full
Johns Hopkins researchers recently identified Borrelia as an antibiotic resistant/tolerant superbug capable of developing round body forms after antibiotic exposure.

Quotes from Dr. Ying Zhang, professor at the Department of Molecular Microbiology and Immunology at the Johns Hopkins Bloomberg School of Public Health:

-What has tuberculosis and Borrelia burgdorferi in common? In the late stage of the disease occurs persistent (tolerant) bacteria, which essentially means that the bacteria lasts and lasts and lasts. They protect themselves against antibiotics and are difficult to treat.

– Both Borrelia burgdorferi and tuberculosis is relatively easy to cure in the early stages, even with the use of one antibiotic. In the late stage it is impossible to cure the disease with the same type of treatment in the acute phase, said Dr. Ying Zhang when he visited the year NorVect conference.

20. Researchers’ discovery may explain difficulty in treating Lyme disease
http://www.northeastern.edu/news/2015/06/researchers-discovery-may-explain-difficulty-in-treating-lyme-disease/

Excerpt:

“Northeastern University researchers have found that the bacterium that causes Lyme disease forms dormant persister cells, which are known to evade antibiotics.”

21. Evidence of in vivo existence of Borrelia biofilm in borrelial lymphocytomas
UNH Discovers Biofilm in Those Affected by Lyme Disease

Excerpt:
“An article by a UNH research team led by Professor Eva Sapi is the first to show that the microorganisms that cause Lyme disease are resistant to treatment due to what’s called a biofilm. A biofilm – which has a protective layer of “slime” – allows the organisms to hide away from antibiotics at the microscopic level.”

22. Notes and Observations on Cell Wall Deficient Forms. By Tom Grier
http://www.lymeneteurope.org/info/cell-wall-deficient-bacteria
This area of microbiology has long been neglected, and we are now paying a price for that neglect. Dr. Mattman’s work suggests that cell wall deficient forms are prevalent, and pathogenic.