Archive for the ‘Viruses’ Category

Pathogenic Priming Nearly Six Years Out

https://popularrationalism.substack.com/p/pathogenic-priming-nearly-six-years?

Pathogenic Priming Nearly Six Years Out: What Do We Know?

The question in 2026 is no longer whether pathogenic priming is biologically plausible. The question is: What do we do about it?

In April 2020, “Pathogenic priming likely contributes to serious and critical illness and mortality in COVID‑19 via autoimmunity” introduced a specific concept, backed by data, that repeated exposure to immunogenic viral epitopes that share homology with human proteins would likely prime the immune system toward pathogenic autoimmunity, with consequences that extend beyond acute infection to multi‑system disease and long‑term morbidity.

That paper, funded by the public via IPAK, did not merely assert that “molecular mimicry is possible.” It catalogued predicted autoreactive homology between SARS‑CoV‑2 epitopes and human proteins across immune‑relevant pathways, showed that only one immunogenic epitope lacked human homology, and explicitly warned that exposure by infection or injection carried foreseeable autoimmune risk if those homologous regions were used uncritically in antigen design.¹

Nearly six years later, the literature citing that work no longer sits at the level of conjecture. It contains experimental demonstrations of antibody cross‑reactivity, functional autoantibodies with physiological effects, validated biomarker panels that discriminate post‑acute sequelae of COVID‑19 (PASC), post‑vaccination prolonged‑symptom cohorts with defined autoantibody signatures, tissue‑level immune injury documented at autopsy, and population‑scale shifts in autoimmune disease incidence. The question in 2026 is no longer whether pathogenic priming is biologically plausible. The question is which parts of the causal chain have been empirically observed, which endpoints are now measurable, and where precision still fails.

This article synthesizes that record using the PubMed‑indexed citation corpus associated with the original 2020 paper, frozen as of January 2026, and focuses on what has been observed, not merely predicted.  (See link for article)

____________

**Comment**

Weiler and others warned us about pathogenic priming repeatedly.

And here is Weiler’s paper which provides an assessment of potential for human pathogenesis via autoimmunity via exposure, via infection or injection.  Potential has now become reality with measurable evidence.

Now the goal should be to find therapies to alleviate or reverse this autoimmunity caused by exposure to unsafe epitopes.

The evidence is clear.  Important quote:

Pretending otherwise is no longer scientifically defensible. ~ James Lyons Weiler

For more:

 

 

 

20 Year Architecture Behind Pandemics As a Business Model With Bill Gates at the Center

https://sayerji.substack.com/p/breaking-the-epstein-files-illuminate

BREAKING: The Epstein Files Illuminate a 20-Year Architecture Behind Pandemics as a Business Model—With Bill Gates at the Center of the Network

Inside the JPMorgan–Gates–Epstein Pipeline: Donor-Advised Funds, Vaccine Finance, and the Architecture of Pre-Positioned Profit
The latest DOJ batch of Epstein files reveal that by the time the world encountered COVID-19, the financial, philanthropic, and institutional machinery to manage—and profit from—a pandemic was already firmly in place.

While the Epstein files have reignited scrutiny around specific relationships, their deeper significance lies in how they intersect with a much longer and largely unexamined timeline. Public records, institutional initiatives, and financial instruments indicate that the conceptual foundations of pandemic preparedness as a managed financial and security category began to take shape in the late 1990s and early 2000s, as philanthropic capital, global health governance, and risk finance increasingly converged. Following the 2008 financial crisis, this framework rapidly accelerated—expanding through reinsurance markets, parametric triggers, donor-advised funding structures, and global simulations—years before COVID-19 made the architecture visible to the public.

What This Investigation Examines—and What It Does Not

This investigation is not concerned with the origins of COVID-19 itself. Rather, it examines what was already in place before it arrived. Drawing on internal emails, financial agreements, text messages, and planning documents—particularly from the 2011–2019 period, when many of these systems moved from conceptual to operational—the record shows that pandemics and vaccines were already being treated as standing financial and strategic categories. Investment vehicles, donor-advised fund structures, simulation programs, and reinsurance products were not improvised in response to crisis; they were refined and expanded within an architecture whose foundations predate the COVID-19 era by more than a decade. Exercises such as Event 201 make clear that coronavirus pandemics were not hypothetical abstractions, but explicitly modeled scenarios—integrated into financial, philanthropic, and policy planning well before COVID-19 emerged.

Executive Summary

  • Vaccines as capital strategy: Internal JPMorgan emails from 2011 show Jeffrey Epstein advising the bank’s most senior executives on how to pitch a Gates-anchored donor-advised fund, insisting the presentation include the phrase “additional money for vaccines” and directing the creation of an “offshore arm — especially for vaccines.”
  • Pandemics as a funding vertical: A 2017 email thread between Epstein, Gates, and Boris Nikolic names “pandemic” as a “key area” for donor-advised fund structures—three years before COVID-19.
  • Pandemic simulation as career currency: A January 2017 iMessage thread from Epstein’s phone shows an associate listing “pandemics (just did pandemic simulation)” as a professional credential—while simultaneously discussing career placement into Gates’ private office, Boris Nikolic’s Biomatics Capital, Merck’s vaccine team, and Swiss Re’s pandemic reinsurance products.
  • Crisis as investable asset: A Gates Foundation briefing describes the Global Health Investment Fund as an “impact investment” vehicle targeting five-to-seven percent returns on drugs and vaccines, backed by a sixty percent principal guarantee.
  • Simulation as technical deliverable: A 2017 internal scope document from bgC3, Gates’ private office, lists “strain pandemic simulation” alongside neurotechnology and national defense applications.
  • The pandemic preparedness network: A 2015 Gates Foundation letter confirms pandemic preparedness coordination with the International Peace Institute—led by Terje Rød-Larsen, a documented Epstein dinner guest—while Epstein separately feeds Rød-Larsen Gates’s public pandemic messaging.

(See link for article)

_____________

**Comment**

It’s all right here folks, in bright purple crayon.

For  more:

 

 

White House Keeps Ties to WHO Flu System, CA Joins WHO Global Outbreak Network & Study Shows Most People Have Immune Defenses Against H5N1

https://jonfleetwood.substack.com/p/trump-admin-keeps-ties-to-who-influenza?

Trump Admin Keeps Ties to WHO Influenza System as U.S. Funds Bird Flu Gain-of-Function and Mass Vaccine Programs

Despite claiming to have withdrawn from the international organization.

Despite claiming to have formally withdrawn from the World Health Organization (WHO), the Trump administration has confirmed it is still in active discussions with the agency about participating in next year’s global influenza vaccine strain-selection process—at the same time the U.S. government is funding influenza bird flu gain-of-function research and a $500 million influenza vaccine initiative.

On January 22, the U.S. Department of Health and Human Services (HHS) announced that the United States had completed its withdrawal from the WHO, apparently ending all funding, recalling U.S. personnel, and terminating participation in WHO committees, governance bodies, and technical working groups.

During the same briefing, administration officials acknowledged that influenza remains an open channel for engagement.

Per CNN’s Thursday report:

“HHS left the door open to some continued collaboration, however. Asked if the US would participate in an upcoming WHO-led meeting to decide the composition of next year’s flu vaccines, the administration said conversations about that are still ongoing.”

The statement was made during a call with reporters following the withdrawal announcement.

This places influenza in a separate policy category—one where U.S. withdrawal exists on paper, but coordination with the same international decision system continues.

It raises questions about who is actually setting U.S. influenza policy, and why the one disease tied to global strain forecasting, pandemic modeling, and mass countermeasure production remains exempt from the break. (See link for article)

Important quote:

….despite the publicized WHO withdrawal, the United States remains functionally embedded in the WHO-centered influenza system—where global strain selection, federally funded virus engineering, and government-backed vaccine platforms converge inside the same international pandemic planning architecture.

And more bad news….

California Becomes First State to Join WHO’s Global Outbreak Response Network After US Exit

Important excerpt:

Newsom, who confirmed in October that he’s considering a 2028 presidential bid, revealed the new collaboration after meeting with WHO Director-General Dr. Tedros Adhanom Ghebreyesus at the World Economic Forum in Switzerland.

It will be interesting to learn where California’s money to fund this ‘network,’ comes from since $111 MILLION in U.S. mandatory annual dues and $570 MILLION in “voluntary contributions” has come to an end.

https://jonfleetwood.substack.com/p/most-people-already-have-immune-defenses?

Most People Already Have Immune Defenses Against H5N1 Bird Flu: Journal ‘Immunity’

94% had H5 antibodies, 100% showed neutralization despite no exposure to virus.

A new peer-reviewed study published last week in the journal Immunity reports that the vast majority of people already carry antibodies capable of neutralizing the cattle-linked purported H5N1 bird flu virus, despite having no known exposure to H5N1 and being classified as immunologically naïve.

The findings challenge the widespread assumption that humans are broadly unprotected against H5N1—an assumption that has underpinned recent pandemic warnings tied to the virus’s spread in U.S. dairy cattle.

It also challenges the justification for government-led gain-of-function bird flu experiments and mass vaccine development programs built on the premise that humans have little to no existing immunity, including the Trump administration’s $500 million “next-generation, gold-standard” bird flu vaccine effort.

Study Finds Antibodies in Nearly All Unexposed Individuals

Researchers analyzed blood samples from 66 individuals in Germany with no known exposure to H5N1.

Using multiple laboratory tests, the study found that 94% had detectable IgG antibodies that bind to the H5 hemagglutinin protein, while 100% showed measurable neutralizing activity against the cattle-associated H5N1 strain A/Texas/37/2024 in a sensitive neutralization system.  (See link for article)

______________

Important excerpt:

While the study does not address transmission dynamics, it clearly demonstrates that baseline human immunity to H5N1 already exists—raising questions about whether current levels of alarm, experimentation, and preemptive intervention are scientifically justified.

Our government has been funding, to the tune of $500 million, for a ‘next generation’ pandemic vaccine project (BPL-1357 and BPL-24910), as well as gain-of-function bird flu viruses.

Both jabs claim to protect against bird flu, the very virus the government has been mutating in the lab with Bill Gates. Source

Government MO: create a problem, then provide the answer and solution that they will profit from.

Seems nothing has been learned from COVID; another gain-of-function experiment the government funded with taxpayer dollars that they profited from.

For more:

Gates has his fingers in so many pies it’s hard to keep them all straight:

      • infectious diseases yielding lucrative government contracts
      • vaccines – ignoring vaccine safety, encouraging pregnant women to get the fast-tracked, experimental COVID gene therapy, and promoting censorship on vaccine debate   Source
      • family planning
      • agriculture
      • climate change
      • food ‘security’
      • GMO research including ‘terminator seed’ projects, synthetic meat startups, and releasing GMO insects
      • the media – from BBC, NPR, The NY Times, The Atlantic, The Guardian, and much more to ‘fact’ checkers who silence online dissent.

Lyme Disease Co-Infections: What You Need to Know

https://danielcameronmd.com/coinfections-backup/

Lyme Disease Loneliness
Jan31

Lyme Disease Co-infections: What You Need to Know

Lyme disease co-infections occur when a single tick bite transmits multiple pathogens. Up to 40% of Lyme patients in some regions also carry Babesia, Bartonella, Anaplasmosis, or Ehrlichia—yet these infections are frequently missed.

When co-infections go unrecognized, patients don’t fully recover. Standard Lyme treatment won’t clear a parasite like Babesia or intracellular bacteria like Anaplasmosis. Understanding lyme disease co-infections is essential for anyone who isn’t getting better despite treatment.


Why Co-infections Matter

Ticks don’t carry just one pathogen—they can harbor several at once. A single bite can transmit:

  1. Bacteria — Borrelia (Lyme), Anaplasma, Ehrlichia, Bartonella
  2. Parasites — Babesia species
  3. Viruses — Powassan, others

Co-infections typically make symptoms more severe, treatment more complicated, and recovery longer. Patients with multiple infections often experience symptoms that don’t fit neatly into one diagnosis—which leads to confusion, misdiagnosis, and delayed care.

If you’ve been treated for Lyme disease but still feel sick, a co-infection may be the reason.


Babesia

Babesia is a malaria-like parasite that infects red blood cells. It’s the most common Lyme disease co-infection in the Northeast and Midwest, with up to 40% of Lyme patients in some areas also testing positive.

Key symptoms:

  1. Drenching night sweats
  2. Air hunger (shortness of breath with normal oxygen)
  3. Profound fatigue beyond typical Lyme exhaustion
  4. Cycling fevers and chills

Why it’s missed: Standard Lyme antibiotics don’t work against Babesia. Patients improve on doxycycline, then relapse—because the parasite was never treated.

Treatment: Requires antiparasitic medications (typically atovaquone + azithromycin), not standard Lyme antibiotics.

Babesia Resources

→ Babesia and Lyme: What Patients Need to Know — Comprehensive guide with 57 articles covering symptoms, testing, treatment, and more.


Bartonella

Bartonella species cause several human diseases, most famously “cat scratch fever.” While traditionally associated with flea bites and cat scratches, Bartonella has been found in ticks—including black-legged ticks that transmit Lyme.

Key symptoms:

  1. Streak-like rash (in some patients)
  2. Swollen lymph nodes
  3. Neuropsychiatric symptoms — anxiety, irritability, rage
  4. Fatigue, headaches, fever

Why it’s missed: Testing is unreliable, and many physicians don’t consider tick-borne Bartonella. Psychiatric symptoms may be attributed to stress or mental illness rather than infection.

Related Reading: Bartonella

  1. Case Reports: Bartonella Associated with Psychiatric Symptoms
  2. ALS and MS Suspected in Woman Later Diagnosed with Bartonella and Lyme
  3. Babesia Bartonella: Neuropsychiatric Symptoms in Children

Anaplasmosis

Anaplasmosis (formerly Human Granulocytic Ehrlichiosis) is caused by the bacterium Anaplasma phagocytophilum. It’s transmitted by the same black-legged tick that carries Lyme disease.

Key symptoms:

  1. High fever, chills
  2. Severe headache
  3. Muscle aches
  4. Fatigue, malaise

Why it’s missed: Symptoms overlap with Lyme and other flu-like illnesses. Without specific testing, Anaplasmosis is often overlooked—especially when Lyme is already diagnosed.

Treatment: Responds to doxycycline, the same antibiotic used for Lyme. However, treatment duration and monitoring may differ when co-infection is present.

Related Reading: Anaplasmosis
  1. Babesia Anaplasmosis: Cognitive Impairment in Co-infection
  2. Tick Bite Multiple Co-infections: One Bite, Many Pathogens

Ehrlichia

Ehrlichiosis is caused primarily by Ehrlichia chaffeensis and transmitted by the Lone Star tick. It attacks white blood cells, potentially causing severe illness if untreated.

Key symptoms:

  1. Fever, headache
  2. Fatigue, muscle aches
  3. Nausea, vomiting
  4. Confusion (in severe cases)

Why it’s missed: Similar presentation to Anaplasmosis and other tick-borne diseases. Geographic distribution differs—Ehrlichiosis is more common in the Southeast and South-Central U.S.

Treatment: Doxycycline is the treatment of choice. Delayed treatment can lead to hospitalization.


Other Tick-Borne Infections

The list of tick-borne diseases continues to grow:

  1. STARI (Southern Tick-Associated Rash Illness) — EM-like rash from Lone Star tick, causative agent unknown
  2. Rocky Mountain Spotted Fever — Severe, potentially fatal if untreated
  3. Powassan Virus — Rare but serious neurological infection
  4. Borrelia miyamotoi — Relapsing fever-like illness
  5. Rickettsiosis — Various spotted fever group infections

When to Suspect Co-infections

Consider lyme disease co-infections if:

  1. Symptoms are unusually severe
  2. You’re not improving with standard Lyme treatment
  3. You relapse after completing antibiotics
  4. Night sweats, air hunger, or high fevers are prominent
  5. Neuropsychiatric symptoms don’t fit the typical Lyme pattern

Co-infections don’t always show up on tests. Clinical judgment—based on symptoms, exposure history, and treatment response—often guides diagnosis.


Frequently Asked Questions

Can you get multiple infections from one tick bite?

Yes. A single tick can carry several pathogens simultaneously, transmitting them all in one bite. This is why co-infections are so common in Lyme patients.

Why don’t standard Lyme antibiotics work for all co-infections?

Lyme disease is bacterial, but Babesia is a parasite—it requires antiparasitic medications. Bartonella may need different antibiotics than those used for Lyme. Each pathogen requires targeted treatment.

How are co-infections diagnosed?

Testing exists for most co-infections, but sensitivity varies. Blood smears, PCR, and antibody tests each have limitations. Clinical diagnosis based on symptoms is often necessary.

Do co-infections make Lyme disease worse?

Yes. Studies show that patients with co-infections experience more severe symptoms, longer illness duration, and slower recovery than those with Lyme alone.

What if I’ve been treated for Lyme but still feel sick?

Undiagnosed co-infection is one of the most common reasons for persistent symptoms after Lyme treatment. Evaluation for Babesia, Bartonella, and other pathogens should be considered.


Related Resources

  1. Babesia and Lyme: What Patients Need to Know — Complete Babesia hub
  2. Lyme Disease Symptoms
  3. Post-Treatment Lyme Disease Syndrome (PTLDS)
  4. Autonomic Dysfunction in Lyme Disease
  5. Lyme Disease Misconceptions

If you’re struggling with persistent symptoms despite Lyme treatment, co-infections may be part of the picture. Identifying and treating all tick-borne pathogens is often the key to recovery.

For more:

Deadly Hospital Protocols Caused Nearly Half a Million Excess Deaths in 2020

Deadly Hospital Protocols Caused Almost 20% Excess Deaths in 2020

By John Beaudoin

In this 10 minute video, John Beaudoin explains CDC mortality data from 2018 – 2023. The largest increase in death happened between 2019 and 2020 – nearly a 20% increase in mortality before the gene therapy injection rollout.

Almost none of these deaths were caused by Covid but by deadly hospital treatment protocols that Covid patients were subjected to. These protocols were issued as guidelines by the NIH and heavily incentivized by the federal health agencies with lavish reimbursements and extravagant bonus payments.

The system that made these hospital murders they declared ‘COVID deaths’ possible, is still in place today.

Ken McCarthy‘s book, ‘What the Nurses Saw: An Investigation into Systemic Medical Murders That Took Place in Hospital During the COVID Panic and the Nurses Who Fought Back to Save Their Patients,’ gives a first hand accounts by nurses that stated they didn’t see a SINGLE patient die from COVID.

Instead of effective treatments like vitamin C, D, HCQ, ivermectin, and steroids for cytokine cascades they were given Remdesivir which is ineffective, and previously pulled for high death rates, and were intubated, which caused 70% of COVID deaths alone.

“Specifically in the US, they incentivized a protocol which virtually guaranteed that people that came to the hospital with respiratory problems were going to die. Not everyone died, but over a million people died in US hospitals.

And he adds: “It was systematized and it was incentivized by the federal government of the United States.” ~ Ken McCarthy

Then in 2021 when 70% of the population received toxic gene therapy injections, excess mortality went up more, but it’s virtually impossible to parse out how much was due to hospital protocols or how much was from the COVID gene therapy shots due to the CDC’s inaccurate coding of death certificates.

The CDC systematically misclassified COVID as the underlying cause of death (UCod) even when a different condition was listed.

And the code issued by the WHO in January 2021 to be used exclusively for COVID ‘vaccine’ caused death wasn’t used at all by the CDC.  

This is how health officials got away with proclaiming there was not a single COVID ‘vaccine’ death.

The only reason some COVID ‘vaccine’ deaths are even coded is due to some brave doctors who dared to list the nmRNA shots as the cause of death on the death certificate.

Further mudding the waters, such deaths are coded with Y59.0., which is meant to be used for adverse events of viral vaccines, which the mRNA vaccines are not, so death by the mRNA Covid-19 vaccines were thrown in with viral vaccines, making it impossible to distinguish whether death was caused by a viral vaccine or an mRNA gene therapy injection.

Please see this video: The Uncounted COVID-19 Vaccine Injuries 

“More people died in excess from pneumonia in the third wave of Covid than in the first or the second. How does that make any sense? Because they wrecked their immune systems with a vaccine that goes into your bone marrow and your lymph and destroys your ability to create appropriate white cells that will attack a disease. It reprograms your immune system to fight something that doesn’t even exist anymore in society, an old variant of COVID.” ~ John Beaudoin

No wonder nobody wants to talk about this. This cannot be buried. People must know.  Those responsible must be held accountable.

If not, way more people are going to be killed next time.

It’s important to note that infant deaths to vaccines are NEVER listed on death certificates because a specific ICD code doesn’t exist.  They’ve been misclassifying vaccine deaths as SIDS (Sudden Infant Death Syndrome) for decades.  The CDC lists 131 causes of childhood deaths but omits vaccines.

Another way the CDC obfuscates vaccine data is by classifying 95% of measles cases as ‘unvaccinated or unknown’ two fundamentally different categories.

Truth be told, measles cases with unknown vaccination status may in fact be vaccinated.

The CDC purposely merges unknown cases with unvaccinated ones maximizing the association between measles cases and non-vaccination while obscuring uncertainty in the data.  It purposely does not apply the same logic in reverse – merging ‘unknown cases with vaccinated cases maximizing the association between measles cases and vaccination, which very well could be true.

This allows them to smugly reinforce a predetermined narrative.

The MMR vaccine contains a live measles virus that was created through a laboratory process U.S. military biodefense experts state “could be considered, by current definitions, gain-of-function research.”  Peer-reviewed studies further document vaccine-strain replication and shedding, measles-like illness following vaccination, and frequent inability to distinguish vaccine-strain illness from wild measles in symptomatic cases.

For more: