Archive for the ‘vaccines’ Category

The Lyme Vaccine & Russian Roulette

https://www.change.org/p/1120418/u/22849266?utm_medium=email&utm_source=petition_update&utm_campaign=350132&sfmc_tk=GM

The Lyme vaccine and RUSSIAN ROULETTE

Carl Tuttle
Hudson, NH
JUN 7, 2018 — There has been a recent increase in news articles regarding Lyme disease vaccines. A number of attempts to get the editors to correct the disinformation have failed to produce full disclosure.

It is believed that a rush to create a Lyme disease vaccine led to the mishandling of the disease. Current antibody tests for Lyme disease were manipulated in 1994 at the Dearborn Conference so as to facilitate vaccine development. The two most important indicators of infection were stripped out of serology tests so that the vaccinated would test seronegative. The vast majority of truly infected patients cannot obtain a timely diagnosis leading to a missed opportunity for successful short term treatment.

The vaccine known as LYMErix was supposed to expose the immune system to the outer surface protein A (OspA) of the spirochete responsible for causing Lyme disease but for some patients, it caused the same crippling effects of the disease itself as reported in the class action lawsuit:

https://www.dropbox.com/s/sodqs3pdeeesktf/Sheller%20Lymerix.pdf?dl=0

Excerpt from the lawsuit:

“The people who have contacted us were, prior to vaccination with LYMErix, healthy, active and energetic. Indeed, the very reason they sought the LYMErix vaccine was their desire to preserve their healthy, active lifestyle. However, what they experienced was a dramatic degradation of their health and quality of life. As will be described below, these previously healthy individuals are now afflicted with painful, at times debilitating arthritic symptoms, including joint pain and swelling, as well as extremely severe Lyme-disease-like symptoms which have persisted to this day.”

Below is the link to the Final Judgement and Approval of the class action against SmithKline Beecham as a settlement was awarded to these individuals.

JUDGEMENT, FINAL ORDER AND DECREE GRANTING FINAL APPROVAL OF THE CLASS ACTION SETTLEMENT:

https://www.lymediseaseassociation.org/images/NewDirectory/Government/Vaccines/2003_Vaccine_Judgement_Final_Sttle_Apprvl..pdf

The Principle Investigators of the two previous Lyme vaccines: Allen C. Steere for SmithKline Beecham’s LymeRix and Gary Wormser for Connaught’s vaccine (which never made it to market) have conceptualized a disease that would enable vaccine development. The one-size-fits-all Lyme treatment guideline (lead author: Gary Wormser) matches the conceptualized disease. This is a flagrant conflict of interest.

Post-treatment Lyme disease syndrome is simply a fabricated medical condition disguising treatment failure.

The fraudulent handling of Lyme disease has now been exposed through a recent racketeering lawsuit against the academics that have controlled the Lyme disease narrative for the past thirty years including Wormser and Steere.

You can read the court document here: https://www.courthousenews.com/wp-content/uploads/2017/11/LymeDisease.pdf

A chronic relapsing seronegative disease does not fit the vaccine model so chronic Lyme which is completely devastating to the patient is not recognized and there is no treatment. The disabled Lyme patient is left to fend for himself because treating this class of patient became too expensive as outlined in the racketeering lawsuit. There is a growing community of horribly disabled patients whose disability has gone unrecognized for three decades.

Here’s yet another victim:

Nicole Malachowski: Unfit for Duty from Debilitating Tick-Borne Disease
http://cdmrp.army.mil/cwg/stories/2018/nicole_malachowski_profile

“Her medical retirement, however, was premature. At only 43 years old, she was deemed unfit for duty due to neurological damage from tick-borne illness.”

_____________________________

The latest vaccine from French drug manufacturer Valneva is another OspA vaccine similar to LYMErix so the possibility exists that the class of patient who experienced the debilitating effects of LYMErix could end up with the same results. There was no attempt to uncover why LYMErix disabled the patient as described in the class action. Until we fully understand how Lyme disease disables its victim aren’t we playing Russian roulette with people’s health?

Please distribute this petition update far and wide through social media as the public needs to know the truth and will not obtain this information through fake news outlets.
The following letters to the editors failed to produce full disclosure:

#1 PRECISSION VACCINATIONS

——— Original Message ———-
From: Carl Tuttle
To: DonaldHackett@gmail.com, Don@PrecisionVax.com
Cc: Karen@PrecisionVax.com, DReiter@PrecisionVaccinations.com, sitka@outlook.com
Date: May 29, 2018 at 10:03 AM
Subject: Morris County Is New Jersey’s Hot-Spot for Lyme Disease

Morris County Is New Jersey’s Hot-Spot for Lyme Disease
https://www.precisionvaccinations.com/valneva-lyme-disease-vaccine-candidate-vla15-designed-increase-antibodies-prevent-borrelia-migrating

-Valneva Lyme disease vaccine candidate VLA15 is designed to increase antibodies that prevent Borrelia from migrating from ticks to humans

-John Halperin, MD, medical director of Atlantic Neuroscience Institute said, “Ticks have to stay attached for 24 to 48 hours before you’re at serious risk of Lyme disease.”

May 29, 2018

To; PrecisionVaccinations
Attn: Don Ward Hackett, Managing Editor

Dear Mr. Hackett,

There are multiple issues with your recent article regarding New Jersey’s Hot-Spot for Lyme disease.

Valneva’s vaccine is based on the failed OspA vaccine known as LYMErix which was withdrawn from the market by the manufacturer not for poor sales as reported in the media but for the severe and debilitating adverse reactions it produced.

Excerpt from the class action lawsuit: (See attached court document)

“The people who have contacted us were, prior to vaccination with LYMErix, healthy, active and energetic. Indeed, the very reason they sought the LYMErix vaccine was their desire to preserve their healthy, active lifestyle. However, what they experienced was a dramatic degradation of their health and quality of life. As will be described below, these previously healthy individuals are now afflicted with painful, at times debilitating arthritic symptoms, including joint pain and swelling, as well as extremely severe Lyme-disease-like symptoms which have persisted to this day.”

______________________________________

Regarding John Halperin’s statement: “Ticks have to stay attached for 24 to 48 hours before you’re at serious risk of Lyme disease.”

This statement is a continuation of the disinformation campaign which is part of a long running racketeering scheme identified in the Shrader & Associates RICO lawsuit. It should be noted that John Halperin, MD is one of the defendants named in this lawsuit.

You can read the court document here: https://www.courthousenews.com/wp-content/uploads/2017/11/LymeDisease.pdf

Please see the following information regarding transmission times:

1. Clinical evidence for rapid transmission of Lyme disease
following a tickbite

Eleanor D. Hynote, Phyllis C. Mervine, Raphael B. Stricker
Diagnostic Microbiology and Infectious Disease, online
before print, November 20, 2011.

http://dx.doi.org/10.1016/j.diagmicrobio.2011.10.003

Abstract

Lyme disease transmission to humans by Ixodes ticks is
thought to require at least 36–48 h of tick attachment. We
describe 3 cases in which transmission of Borrelia
burgdorferi, the spirochetal agent of Lyme disease, appears
to have occurred in less than 24 h based on the degree of
tick engorgement, clinical signs of acute infection, and
immunologic evidence of acute Lyme disease.

Health care providers and individuals exposed to ticks
should be aware that transmission of Lyme disease may occur
more rapidly than animal models suggest. A diagnosis of Lyme
disease should not be ruled out based on a short tick
attachment time in a subject with clinical evidence of B.
burgdorferi infection.

2. How Long Does A Tick Need To Be Attached To Transmit Lyme Disease?
https://sites.google.com/site/marylandlyme/ticks/how-long-to-transmit

Michael Cook reports- “The claims that removal of ticks within 24 hours or 48 hours of attachment will effectively prevent LB are not supported by the published data, and the minimum tick attachment time for transmission of LB in humans has never been established.”

___________________

From the PrecisionVaccinations.com website:

“If our audiences cannot trust us to get the small things right, how can they trust us on the big things?”

Precision Vaccination’s article requires the truth not more disinformation.

Sincerely,

Carl Tuttle
Lyme Endemic Hudson, NH 03051 (USA)

______________________________

#2 THE BOSTON GLOBE:

——— Original Message ———-
From: Carl Tuttle
To: letter@globe.com
Cc: oped@globe.com
Date: June 4, 2018 at 1:31 PM
Subject: How Mass. could disrupt Lyme disease research

How Mass. could disrupt Lyme disease research
https://www.bostonglobe.com/opinion/editorials/2018/06/01/how-mass-could-disrupt-lyme-disease-research/3QuoqWUcwp0SEHegejCxDK/amp.html?event=event25&__twitter_impression=true

“The need for three shots in a single year, feared links to arthritis, and the spread of unfounded anti-vaccine conspiracy theories have most likely left a permanent taint on the idea of a vaccine for the long term, researchers believe.”

June 4, 2018

Letters to the Editor
The Boston Globe
PO Box 55819
Boston, MA 02205

To the Editor,

In reference to the statement above; “unfounded anti-vaccine conspiracy theories” the first Lyme disease vaccine known as LYMErix was withdrawn from the market by the manufacturer not for poor sales as reported in the media but for the severe and debilitating adverse reactions it produced.

Excerpt from the class action lawsuit: (See attached court document)

“The people who have contacted us were, prior to vaccination with LYMErix, healthy, active and energetic. Indeed, the very reason they sought the LYMErix vaccine was their desire to preserve their healthy, active lifestyle. However, what they experienced was a dramatic degradation of their health and quality of life. As will be described below, these previously healthy individuals are now afflicted with painful, at times debilitating arthritic symptoms, including joint pain and swelling, as well as extremely severe Lyme-disease-like symptoms which have persisted to this day.”

Below is the link to the Final Judgement and Approval of the class action against SmithKline Beecham as a settlement was awarded to these individuals.

JUDGEMENT, FINAL ORDER AND DECREE GRANTING FINAL APPROVAL OF THE CLASS ACTION SETTLEMENT:
https://www.lymediseaseassociation.org/images/NewDirectory/Government/Vaccines/2003_Vaccine_Judgement_Final_Sttle_Apprvl..pdf

Whoever wrote the Editorial in the Boston Globe certainly didn’t get their facts straight and a correction should be published.

Carl Tuttle
Lyme Endemic Hudson, NH

Dear Mr. Bernstein,

I received the standard response from my letter to the editor but I think you will agree that my letter identifies serious concerns with the first Lyme vaccine and should be shared with the public.

You might want to inquire where the source of the information published in the Globe originated from in that editorial.

Sincerely,

-Carl Tuttle
Hudson, NH

___________________________________

#3 CAUDWELL LYMECO CHARITY:

My view on the development of a Lyme disease vaccine
By John Caudwell, Chairman of Caudwell LymeCo Charity
https://caudwelllyme.com/2018/06/05/my-view-on-the-development-of-a-lyme-disease-vaccine/comment-page-1/#comment-730

Carl Tuttle
June 5, 2018 at 12:44 pm

Your comment is awaiting moderation.

The first Lyme disease vaccine known as LYMErix was withdrawn from the market by the manufacturer not for poor sales as reported in the media but for the severe and debilitating adverse reactions it produced. Valneva’s vaccine is based on the same OspA concept that was used in LYMErix.

Excerpt from the class action lawsuit:

“The people who have contacted us were, prior to vaccination with LYMErix, healthy, active and energetic. Indeed, the very reason they sought the LYMErix vaccine was their desire to preserve their healthy, active lifestyle. However, what they experienced was a dramatic degradation of their health and quality of life. As will be described below, these previously healthy individuals are now afflicted with painful, at times debilitating arthritic symptoms, including joint pain and swelling, as well as extremely severe Lyme-disease-like symptoms which have persisted to this day.”

Below is the link to the Final Judgement and Approval of the class action against SmithKline Beecham as a settlement was awarded to these individuals.

JUDGEMENT, FINAL ORDER AND DECREE GRANTING FINAL APPROVAL OF THE CLASS ACTION SETTLEMENT:
https://www.lymediseaseassociation.org/images/NewDirectory/Government/Vaccines/2003_Vaccine_Judgement_Final_Sttle_Apprvl..pdf

Carl Tuttle
Lyme Endemic Hudson, NH USA
________________________________________

#4 ZME SCIENCE

———- Original Message ———-
From: Carl Tuttle
To: andrei@zmescience.com
Date: June 6, 2018 at 1:27 PM
Subject: Lyme Disease vaccine set to become available soon, as first trials successfully passed

Lyme Disease vaccine set to become available soon, as first trials successfully passed
BY MIHAI ANDREI
https://www.zmescience.com/medicine/lyme-disease-vaccine-28052018/

Dear Mihai,

Valneva’s vaccine is based on the failed OspA vaccine known as LYMErix which was withdrawn from the market by the manufacturer not for poor sales as reported in the media but for the severe and debilitating adverse reactions it produced.

Excerpt from the class action lawsuit: (See attached court document)

“The people who have contacted us were, prior to vaccination with LYMErix, healthy, active and energetic. Indeed, the very reason they sought the LYMErix vaccine was their desire to preserve their healthy, active lifestyle. However, what they experienced was a dramatic degradation of their health and quality of life. As will be described below, these previously healthy individuals are now afflicted with painful, at times debilitating arthritic symptoms, including joint pain and swelling, as well as extremely severe Lyme-disease-like symptoms which have persisted to this day.”

______________________________________

Below is the link to the Final Judgement and Approval of the class action against SmithKline Beecham as a settlement was awarded to these individuals.

JUDGEMENT, FINAL ORDER AND DECREE GRANTING FINAL APPROVAL OF THE CLASS ACTION SETTLEMENT:
https://www.lymediseaseassociation.org/images/NewDirectory/Government/Vaccines/2003_Vaccine_Judgement_Final_Sttle_Apprvl..pdf

Regarding the mishandling of Lyme disease, a crime has been identified and submitted to the court system here in the United States. There is ample evidence showing that the CDC participated in this scheme through tax payer dollars financing the dishonest science aligning themselves with the defendants.

You can read the court document here: https://www.courthousenews.com/wp-content/uploads/2017/11/LymeDisease.pdf

Will you publish this important information or will you hide it from the reader?

Sincerely,

Carl Tuttle
Lyme Endemic Hudson, NH 03051 (USA)
_________________

**Comment**

For more on the Lyme vaccine:  https://madisonarealymesupportgroup.com/2018/06/06/valneva-seeking-partner-for-350m-lyme-disease-vaccine-effort-prepping-for-phase-2/  (Please read my comment after the article.  This is far from a benign vaccine.  It has caused outright harm – even death)

Tuttle is doing a huge service in Lyme-land but WE ALL need to be doing this.

The misinformation just keeps spewing out of the media like the Pied Piper and WE must correct them.  The world needs to know:

There’s so much that is unknown yet the “authorities” and the media regurgitates ancient, dusty information that was biased to begin with.

 

Valneva Seeking Partner for $350M Lyme Disease Vaccine Effort – Prepping for Phase 2

https://www.fiercepharma.com/vaccines/valneva-investing-350m-lyme-disease-vaccine-ready-for-phase-2-h2-2018

Valneva seeking partner for $350M Lyme disease vaccine effort, prepping for phase 2

**Comment after article**
If you haven’t read Weintrub’s book, do. It’s quite an eye-opener and still highly relevant today even though it was written in 2008. But, a lot has happened since both the 1998 Lyme vaccine and Weintraub’s 2008 book that declares the Lyme vaccine caused “rare” adverse events.
https://madisonarealymesupportgroup.com/2018/04/16/vl15-lyme-vaccine-another-fraud/ THIS VACCINE CAUSED 229 DEATHS, INCLUDING 43 SUICIDES

https://madisonarealymesupportgroup.com/2018/01/28/the-secret-x-files-the-untold-history-of-the-lymerix-vaccine/

https://madisonarealymesupportgroup.com/2017/07/01/pbs-lyme-vaccine/  Did you know that the LYMERIX vaccine caused 640 emergency room visits, 34 life threatening reactions, 77 hospitalizations, 198 disabilities, and 6 deaths? In a vile cesspool of conflicts of interest are university patent holders, drug companies, and the FDA itself as another patent holder. It generated 40 million dollars before it was yanked. (2008, Drymon)
As you can see in Dr. Lapenta’s article, the death toll raised to 229. Besides, death and suicide, please see:
http://www.yourlawyer.com/topics/overview/lymerix One doctor stated that 21 patients developed severe arthritis after receiving the LYMERIX vaccine.
http://www.lymediseaseassociation.org/index.php/about-lyme/controversy/vaccine/261-lymerix-meeting “Given that Dr. Marks lead the clinical trials for Lymerix’s competitor, the OspA vaccine produced and then abandoned by Aventis Pasteur, his conclusions mean a lot. “In my opinion,” he told FDA officials, “there is sufficient evidence that Lymerix is causally related to severe rheumatologic, neurologic, autoimmune, and other adverse events in some individuals. This evidence is such as to warrant a significantly heightened degree of warnings and possible limitations or removal from marketing of Lymerix.”

Dr. Stricker states:
Another Lyme OspA Vaccine Whitewash
The meta-analysis by Zhao and colleagues comes to the conclusion that “the OspA vaccine against Lyme disease is safe and its immunogenicity and efficacy have been verified.” The authors arrive at this sunny conclusion by excluding 99.6% of published articles that demonstrate potential problems with the OspA vaccine. Furthermore, the authors ignore peer-reviewed studies, FDA regulatory meetings and legal proceedings that point to major problems with OspA vaccine safety (1-3). This whitewash bodes ill for future Lyme vaccine candidates because it fosters disregard for vaccine safety among Lyme vaccine manufacturers and mistrust among potential Lyme vaccines.

https://madisonarealymesupportgroup.com/2018/04/28/new-lyme-vaccine-pushed-same-vaccine-corruption-revealed/
Weintraub’s article states that when considering vaccines one has to weigh the risk of the vaccine against the possible adverse reactions – which is true; however, we need to first start with being honest about the number of people with adverse reactions. In doing this, two things are important to keep in mind: 1) All numbers on ALL issues regarding Lyme/MSIDS are notoriously low. 2) ALL numbers on ALL issues regarding vaccines are notoriously low and downplayed.

Since 2008, more has come out about the ability of vaccines to reactivate latent infections: https://madisonarealymesupportgroup.com/2016/04/24/gardasil-and-bartonella/
https://madisonarealymesupportgroup.com/2017/12/02/scottish-doctor-gives-insight-on-lyme-msids/
This is an extremely important point to acknowledge as mainstream medicine STILL hasn’t even accepted the fact Lyme/MSIDS patients are often infected with far more than Lyme (Borrelia) to begin with. The current news that vaccines can activate even latent infections muddies and troubles the waters further and frankly spells doom to Lyme/MSIDS patients.

Personally, every single Lyme/MSIDS patient I know who has undergone vaccination has relapsed. That’s kind of a big deal.

This issue of problems with vaccines has exploded in recent years with new discoveries of contamination: https://madisonarealymesupportgroup.com/2017/10/15/vaccines-and-retroviruses-a-whistleblower-reveals-what-the-government-is-hiding/
https://madisonarealymesupportgroup.com/2018/04/28/italian-lab-shut-down-about-to-testify-about-vaccine-contamination-damage/
This contamination could very well be contributing to disease epidemics, including Lyme/MSIDS: https://madisonarealymesupportgroup.com/2018/03/01/vaccines-could-contribute-to-disease-epidemics-due-to-retrovirus-contamination/
The first-ever study involving a truly unvaccinated population suggests that: fully vaccinated children may be trading the prevention of certain acute illnesses (chicken pox, pertussis) for more chronic illnesses and neurodevelopmental disorders like ADHD and Autism. The scientists also found that children born prematurely, who were vaccinated, were 6.6 times more likely to have a neurodevelopmental disorder. https://madisonarealymesupportgroup.com/2017/05/18/first-peer-reviewed-study-of-vaccinated-vs-unvaccinated-children/
The involvement of heavy metals in vaccines: https://madisonarealymesupportgroup.com/2017/09/19/autism-aluminum-adjuvant-link-corroborated/
https://madisonarealymesupportgroup.com/2018/04/09/a-tale-of-3-metals-the-fate-of-western-civilization-what-we-can-do-about-it/
Lyme/MSIDS patients are finding that similarly to autistic children, they improve once they have chelated for heavy metals. Where are these metals coming from?

 

 

 

Immunoexcitotoxicity as the Central Mechanism of Etiopathology & Treatment of Autism Spectrum Disorders: A Possible Role of Fluoride & Aluminum

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909100/

Surg Neurol Int. 2018; 9: 74.

Published online 2018 Apr 9. doi:  10.4103/sni.sni_407_17
PMCID: PMC5909100
PMID: 29721353

Immunoexcitotoxicity as the central mechanism of etiopathology and treatment of autism spectrum disorders: A possible role of fluoride and aluminum

Abstract
Our review suggests that most autism spectrum disorder (ASD) risk factors are connected, either directly or indirectly, to immunoexcitotoxicity. Chronic brain inflammation is known to enhance the sensitivity of glutamate receptors and interfere with glutamate removal from the extraneuronal space, where it can trigger excitotoxicity over a prolonged period. Neuroscience studies have clearly shown that sequential systemic immune stimulation can activate the brain’s immune system, microglia, and astrocytes, and that with initial immune stimulation, there occurs CNS microglial priming.

Children are exposed to such sequential immune stimulation via a growing number of environmental excitotoxins, vaccines, and persistent viral infections. We demonstrate that fluoride and aluminum (Al3+) can exacerbate the pathological problems by worsening excitotoxicity and inflammation. While Al3+ appears among the key suspicious factors of ASD, fluoride is rarely recognized as a causative culprit. A long-term burden of these ubiquitous toxins has several health effects with a striking resemblance to the symptoms of ASD. In addition, their synergistic action in molecules of aluminofluoride complexes can affect cell signaling, neurodevelopment, and CNS functions at several times lower concentrations than either Al3+ or fluoride acting alone. Our review opens the door to a number of new treatment modes that naturally reduce excitotoxicity and microglial priming.

Table 2. Prevention & amelioration of ASD symptoms

SNI-9-74-g014

Excerpt from conclusion:

Evidence is presented that the abundance of fluoride added to the water worldwide and the widespread availability of aluminum particularly to infants and young children through aluminum containing vaccinations, singly or together as aluminofluoride can be potent factors in producing the condition of immunoexcitotoxicity that leads to the pathological changes seen in ASD. The vaccination program should be evaluated to reduce the excessive stimulation of immature immune system and to replace Al3+-adjuvants.

______________

For more:  https://madisonarealymesupportgroup.com/2017/10/26/clinical-trial-shows-most-kids-with-autism-are-not-born-with-it/

https://madisonarealymesupportgroup.com/2017/09/19/autism-aluminum-adjuvant-link-corroborated/

https://madisonarealymesupportgroup.com/2018/04/09/a-tale-of-3-metals-the-fate-of-western-civilization-what-we-can-do-about-it/

https://madisonarealymesupportgroup.com/2018/05/14/important-background-on-lyme-vaccine-controversy/  But, a lot has happened since both the 1998 Lyme vaccine and Weintraub’s 2008 book that declares the Lyme vaccine caused “rare” adverse events.
https://madisonarealymesupportgroup.com/2018/04/16/vl15-lyme-vaccine-another-fraud/ THIS VACCINE CAUSED 229 DEATHS, INCLUDING 43 SUICIDES
https://madisonarealymesupportgroup.com/2018/01/28/the-secret-x-files-the-untold-history-of-the-lymerix-vaccine/
https://madisonarealymesupportgroup.com/2018/04/16/vl15-lyme-vaccine-another-fraud/
https://madisonarealymesupportgroup.com/2017/07/01/pbs-lyme-vaccine/ Even in 2008, Drymon reported: Did you know that the LYMERIX vaccine caused 640 emergency room visits, 34 life threatening reactions, 77 hospitalizations, 198 disabilities, and 6 deaths? In a vile cesspool of conflicts of interest are university patent holders, drug companies, and the FDA itself as another patent holder. It generated 40 million dollars before it was yanked. (2008, Drymon)
As you can see in Dr. Lapenta’s article, the death toll raised to 229. Besides, death and suicide, please see:
http://www.yourlawyer.com/topics/overview/lymerix One doctor stated that 21 patients developed severe arthritis after receiving the LYMERIX vaccine.
http://www.lymediseaseassociation.org/index.php/about-lyme/controversy/vaccine/261-lymerix-meeting “Given that Dr. Marks lead the clinical trials for Lymerix’s competitor, the OspA vaccine produced and then abandoned by Aventis Pasteur, his conclusions mean a lot. “In my opinion,” he told FDA officials, “there is sufficient evidence that Lymerix is causally related to severe rheumatologic, neurologic, autoimmune, and other adverse events in some individuals. This evidence is such as to warrant a significantly heightened degree of warnings and possible limitations or removal from marketing of Lymerix.”

Dr. Stricker states:
Another Lyme OspA Vaccine Whitewash
The meta-analysis by Zhao and colleagues comes to the conclusion that “the OspA vaccine against Lyme disease is safe and its immunogenicity and efficacy have been verified.” The authors arrive at this sunny conclusion by excluding 99.6% of published articles that demonstrate potential problems with the OspA vaccine. Furthermore, the authors ignore peer-reviewed studies, FDA regulatory meetings and legal proceedings that point to major problems with OspA vaccine safety (1-3). This whitewash bodes ill for future Lyme vaccine candidates because it fosters disregard for vaccine safety among Lyme vaccine manufacturers and mistrust among potential Lyme vaccines.

 

 

 

LD on the Rise – An Expert Explains Why & I Give Rebuttal

I put my **comments** within article.

https://www.ucsf.edu/news/2018/05/410401/lyme-disease-rise-expert-explains-why

Lyme Disease is On the Rise – An Expert Explains Why

By Nina Bai on May 16, 2018

May marks the beginning of the summer season when black-legged ticks that spread Lyme disease are more prevalent – even in California.

Earlier this month, the U.S. Centers for Disease Control and Prevention (CDC) reported that cases of tickborne diseases had more than doubled from 2004 to 2016, from 22,000 to 48,000, and that Lyme disease accounted for 82 percent of tickborne diseases.

Moreover, due to underreporting, the actual number of Lyme disease cases is estimated to be significantly higher – likely more than 350,000 in 2016.

 

chiu-charles_1

Charles Chiu, MD, PhD

We talked to infectious disease expert Charles Chiu, MD, PhD, about the rise in Lyme disease cases, better diagnostic tests on the horizon and what you need to know to protect yourself from infection. Chiu is an associate professor of laboratory medicine and medicine and director of the UCSF-Abbott Viral Diagnostics and Discovery Center.

How common is Lyme disease in California? And why have rates been increasing?

In terms of reported cases, there are about 80 to 100 a year in the state. Residents in or travelers to the northwestern coastal counties – Trinity, Humboldt, and Mendocino – are at highest risk. But because of underreporting, the actual number of Lyme disease cases likely exceeds 1,000 cases a year, simply because most cases of Lyme disease are not reported.

**Comment**  “Exceeds 1,000 cases a year” could mean anything.  California has not been considered an endemic state for decades with patients suffering miserably.  For a great read on why:  https://madisonarealymesupportgroup.com/2018/05/19/infected-ticks-in-california-its-complicated/

There are several potential reasons why rates have increased in California and nationwide. One is globalization. People travel extensively, and for instance, someone could get infected while on the East Coast and come back with Lyme disease.

Another reason is climate change, in that the geographic range of the tick vector, which is the Ixodes or black-legged tick, has expanded westward from the northeast United States as well as southward year after year. For ticks to be maintained in nature, they need to have what we call an animal reservoir, essentially a mammal such as a squirrel or rodent that can harbor Borrelia burgdorferi – the bacterium in the tick that causes Lyme disease. Therefore, expansion of the animal reservoir is also another reason for increasing Lyme disease rates. On the East Coast, the reservoir is the white-footed mouse. In California, the Western gray squirrel harbors the bacterium. Lizards, while not a reservoir for Borrelia burgdorferi, are common hosts for the black-legged tick in California so increase the risk of infections to humans by maintaining the tick population in the wild.

**Comment**  Nope.  According to independent tick expert and researcher, John Scott, climate change has zippo to do with increased infection rates and in fact is part of a nefarious plot to keep monies going toward climate change issues that won’t help sick patients in the least.  Ticks are marvelous ecoadaptors and will be the last species on earth – except for cockroaches & the IRS:  https://madisonarealymesupportgroup.com/2017/08/14/canadian-tick-expert-climate-change-is-not-behind-lyme-disease/

How is Lyme disease transmitted, and is it contagious between humans?

Borrelia burgdorferi causes asymptomatic infection in these small mammal reservoirs. When the ticks feed on mammals carrying Borrelia burgdorferi, these ticks get infected. They can then transmit the infection to humans.

However, humans are considered a dead-end host because the efficiency of transmitting the bacterium to other humans is extremely low. The period during which you can find the bacterium in blood is very brief, generally a few days at most, and blood-borne transmission of Borrelia burgdorferi, such as by transfusion, has never been reported. Borrelia burgdorferi is also not excreted in other body fluids such as sweat, urine, saliva, or respiratory secretions. Lyme disease is therefore not considered contagious.

**Comment**  This is the type of circular reasoning we’ve been dealing with for 40 years.  It was declared in Arkansas that Lyme “wasn’t there” because there weren’t any reports when a mother took her kids to the doctor with every symptom of Lyme known to man.  She wouldn’t let it go and finally they admit that NOW due to this case, Lyme IS in Arkansas:  https://madisonarealymesupportgroup.com/2016/09/24/arkansas-kids-denied-lyme-treatment/.

Also, regarding excretion in bodily fluids, he’s just flat-out wrong.

https://madisonarealymesupportgroup.com/2017/02/24/pcos-lyme-my-story/Bb has been found in semen and vaginal secretions & via milk.  While it’s true they haven’t “conclusively” proven transmission, there has been little research, but many couples claiming to have been infected by their spouse.  To just proclaim it isn’t spread via STD is extremely foolish.

http://www.researchfraud.com/fetal-lyme-borreliosis/

http://www.lymerick.net/Transmission-Bb-contact.htm  Bb found all over the place in animal studies.

http://www.samento.com.ec/sciencelib/4lyme/Townsendhowens.html  Researchers at the University of Wisconsin have reported that dairy cattle can be infected with Bb, hence milk could be contaminated. Bb can also be transmitted to lab animals by oral intake such as food.

https://madisonarealymesupportgroup.com/2018/02/06/lyme-in-the-southern-hemisphere-sexual-transmission/

Compared to other infections, is Lyme disease more difficult to detect and diagnose?

It does appear that Lyme disease is harder to diagnose, and it’s because the Borrelia burgdorferi very rapidly leaves the blood and disseminates into the lymph nodes and into tissues. As a result, blood tests for early Lyme disease have low sensitivity.

Why is it important to accurately diagnose Lyme disease?

Timely and accurate diagnosis of Lyme disease can help prevent potential complications, which include encephalitis, a brain infection; myocarditis, a heart infection; or endocarditis, a heart valve infection.

Is it true that it takes at least 24 hours for a tick to transmit Lyme disease to you?

Yes, this is true. The CDC recommends that patients who notice the tick and remove it within 24 hours do not need antibiotic prophylaxis with doxycycline to prevent Lyme disease transmission. The tick typically needs to be on you, basically sucking your blood and attached to you for 36 to 48 hours, during which the Borrelia burgdorferi migrates from the tick gut to its salivary glands, before it can transmit the Lyme pathogen.

**Comment**  Nope again. For a great read on transmission time:  https://madisonarealymesupportgroup.com/2017/04/14/transmission-time-for-lymemsids-infection/  Only one study done on mice and NO studies on minimum transmission time.  NONE!  Quit stating this as a fact!  In the link you will see a little girl got bit by a tick and within about 6 hours COULDN’T  WALK OR TALK.

So it’s definitely important to find the ticks early and get them off you.

Yes, I recommend that after you go hiking or camping or are otherwise potentially exposed to ticks, that you always do a tick check. The ticks that are most likely to transmit the bacterium are young nymphal ticks. They’re about the size of a poppy seed, so they’re extremely small.

Ticks do not jump or fly. What they do is called “questing,” which means that they wait at the ends of grass or foliage and when you brush by, they’ll immediately latch onto your leg or onto your clothing. But you really need to conduct a tick check all over your body because you won’t necessarily get bitten by the tick where the grass contracted your leg. Ticks can crawl to your armpit or groin and bite there, for instance.

**Comment**  No ticks can’t jump or technically fly but they can drop down from trees.  Birds and rodents land on trees and leave ticks behind. Where do those ticks go?  They can also blow in the air due to strong winds, a lawnmower and/or leaf blower.  They’ve also been found on rocks, underneath picnic tables/benches, and even in caves: https://madisonarealymesupportgroup.com/2017/03/13/ticks-found-on-rocks/  and   https://madisonarealymesupportgroup.com/2017/10/27/israeli-kids-get-lyme-disease-from-ticks-in-caves/ and  https://madisonarealymesupportgroup.com/2018/04/23/tick-borne-relapsing-fever-found-in-austin-texas-caves/

A friend told me ticks blew into their swimming pool from nearby overhanging trees.  I personally had a farmer blow ticks onto my basement screens from his lawnmower.  Some made their way into my house and were crawling on the walls.  Researchers need to quit sounding so “all knowing” and admit there’s much we don’t know.  This TV News anchor got bit at a garden party on a deck with overhanging trees:  https://madisonarealymesupportgroup.com/2017/07/13/tv-anchor-speaks-out-about-lyme-disease/

What percentage of black-legged ticks carry Lyme?

It can be fairly high, anywhere from 2 percent to 15 percent among nymphal ticks in California, depending on the geographic location and season.

**Comment**  A lot more work needs to be done here before just spewing out numbers that sound insignificant.  Let’s put it this way – all it takes is one tick bite to side line you and even kill you.  Take each tick and each bite as seriously as a heart attack.

  • Ticks in California
    The western black-legged tick has been found in 56 of the 58 counties in California.
  • It is common in the humid north coastal areas and on the western slope of the Sierra Nevada range.
  • Ticks prefer cool, moist areas and can be found on wild grasses and low vegetation in both urban and rural areas.
  • Adult ticks climb to the tip of vegetation along trails and wait for a host to brush against them.
  • Nymphs are found in low, moist vegetation such as leaf litter and on logs.
  • Adults are most active from fall through early spring and the nymphs are active primarily in the spring and early summer months.
    Source: California Department of Public Health
How accurate are the current diagnostic tests for Lyme disease? And why do many cases remain undiagnosed?

The current approved testing for Lyme disease is a two-tier serologic test that looks for the generation of antibodies in response to the infection.

But the key limitation of the serologic test in early Lyme disease is that typically an infected individual may take several weeks before he or she is able to mount an antibody response. Therefore, in early Lyme disease, the test sensitivity is only about 30 to 40 percent.

Now after a person generates antibodies after three to four weeks, then the two-tiered serologic test tends to be very sensitive and is good for determining whether a patient was infected.

**Comment**  According to one of the most experienced LLMD’s in Wisconsin, some of the sickest patients NEVER test positive with two-tiered testing and due to the genetic variations, strains, etc., no test will ever be able to pick up all these pathogens infecting us.  Lyme/MSIDS is a clinical diagnosis and doctors need to wake up and become educated on this world-wide scourge.  They can start here:  https://madisonarealymesupportgroup.com/2017/09/05/empirical-validation-of-the-horowitz-questionnaire-for-suspected-lyme-disease/ and

https://madisonarealymesupportgroup.com/2018/06/06/lyme-education-for-healthcare-professionals/ and

https://madisonarealymesupportgroup.com/2018/02/19/calling-all-doctors-please-become-educated-regarding-tick-borne-illness-heres-how/

The take-home message is that we do not have an accurate test for early Lyme disease, and this is why the diagnosis is generally made clinically by a physician and also why there is so much underreporting.

**Comment** None of the testing for Lyme/MSIDS is good.  None.

If a patient presents with fever, a bull’s-eye rash, and during tick season with tick exposure, this, according to CDC criteria, is enough to make a diagnosis of Lyme disease. Part of the reason why laboratory testing isn’t an essential criterion for the diagnosis of Lyme disease is that we simply don’t have a test that is conclusive.

**Comment** There are so many who do NOT present with these symptoms it’s not even funny.  Again, become educated on symptoms and quit relying on outdated and unscientific information.

Your lab is working on better diagnostics for Lyme disease. How is your new test different?

The big area of clinical need is the ability to diagnose early Lyme disease before you can reliably detect it by antibody testing. Usually that window is zero to one month following the tick bite.

About two years ago, we did RNA sequencing of blood samples from patients with Lyme disease to look at the human host response. We looked at the pattern of gene expression in patients following infection, comparing the gene signature of Lyme disease to that for control patients. And we found that Lyme disease, interestingly enough, has a very distinct pattern of human gene expression in response to the infection.

We used this data in a follow-up study – which is currently unpublished – to develop a test with more than 90 percent accuracy in diagnosing early Lyme disease in patients presenting have a fever and rash, generally seven to 10 days after the tick bite.

It’s really a completely new category of diagnostic tests made possible because of advances in sequencing over the past several years.

What is currently the best standard of care for treatment of Lyme disease?

The standard of care for early uncomplicated Lyme disease recommended by the CDC is 10 to 21 days of doxycycline, which is an oral antibiotic that you take twice a day. Patients admitted to the hospital with severe complications of disseminated Lyme disease, such as meningitis or endocarditis, typically receive a two- to four-week course of an intravenous antibiotic such as ceftriaxone.

**Comment**  The question was what is the “best” standard of care?  This is like asking to demonstrate brain surgery in 3-easy lessons.  There is no best standard of care.  This complex illness presents differently on nearly everyone and the exact same drugs will NOT work for some.  People are infected with different things.  Lyme is just the rock star we know by name.  There are many other pathogens involved.  This is NOT a one pathogen one drug illness.  It’s a hodgepodge of things all working together synergistically.  Again, clinical diagnosis, and clinical treatment based on the individual should be the best standard of care.  Anyone saying otherwise is selling something.  The CDC has its head in the sand.

If you get Lyme disease once, can you get it again?

Yes, you can, because protective antibody immunity can wane after several years and you may also be infected by a different strain of Borrelia burgdorferi.

There’s a Lyme disease vaccine for dogs, why isn’t there one for humans?

There actually was a vaccine called LYMErix that was approved by the FDA in 1998. But four years later, it was withdrawn from the market. At the time, there were questions involving the safety of the vaccine, concerns raised by anti-vaccine groups, cost, burdensome vaccination schedule (three doses a year), uncertainty regarding efficacy and need for boosters, and low public demand.

**Comment**  These concerns were not raised by “Anti-vaxxers,” but by patients and doctors over legitimate, documented blow-back the vaccine directly caused. https://madisonarealymesupportgroup.com/2018/04/16/vl15-lyme-vaccine-another-fraud/ THIS VACCINE CAUSED 229 DEATHS, INCLUDING 43 SUICIDES

https://madisonarealymesupportgroup.com/2017/01/26/lyme-vaccine-to-be-tested-on-humans/  The biological mechanism hypothesis was that the outer surface protein A (OspA), which was the antigenic component of the LYMErix vaccine, induced autoimmunity in genetically susceptible individuals, including high levels of autoantibody to OspA in their synovial fluid.

Dr. Stricker states:
Another Lyme OspA Vaccine Whitewash
The meta-analysis by Zhao and colleagues comes to the conclusion that “the OspA vaccine against Lyme disease is safe and its immunogenicity and efficacy have been verified.” The authors arrive at this sunny conclusion by excluding 99.6% of published articles that demonstrate potential problems with the OspA vaccine.  Furthermore, the authors ignore peer-reviewed studies, FDA regulatory meetings and legal proceedings that point to major problems with OspA vaccine safety (1-3). This whitewash bodes ill for future Lyme vaccine candidates because it fosters disregard for vaccine safety among Lyme vaccine manufacturers and mistrust among potential Lyme vaccinees.

https://madisonarealymesupportgroup.com/2018/01/28/the-secret-x-files-the-untold-history-of-the-lymerix-vaccine/
https://madisonarealymesupportgroup.com/2018/04/16/vl15-lyme-vaccine-another-fraud/  Since 2008, more has come out about the ability of vaccines to reactivate latent infections: https://madisonarealymesupportgroup.com/2016/04/24/gardasil-and-bartonella/
https://madisonarealymesupportgroup.com/2017/12/02/scottish-doctor-gives-insight-on-lyme-msids/
This is an extremely important point to acknowledge as mainstream medicine STILL hasn’t even accepted the fact Lyme/MSIDS patients are often infected with far more than Lyme (Borrelia) to begin with. The current news that vaccines can activate even latent infections muddies and troubles the waters further and frankly spells doom to Lyme/MSIDS patients.  Personally, every single Lyme/MSIDS patient I know who has undergone vaccination has relapsed. That’s kind of a big deal.
This issue of problems with vaccines has exploded in recent years with new discoveries of contamination: https://madisonarealymesupportgroup.com/2017/10/15/vaccines-and-retroviruses-a-whistleblower-reveals-what-the-government-is-hiding/

I think that there are now some efforts underway to bring back either this vaccine or other vaccines onto the market, especially given the rise of Lyme disease. This is a disease that infects more than 300,000 people a year, so it’s certainly something for which a vaccine would be really helpful.

**Comment**  RUN AWAY, RUN FAR AWAY!  

Why do some patients with Lyme disease show persistent symptoms, even after being treated for the disease with antibiotics?

A small percentage of patients with Lyme disease – depending on the study, 5 to 15 percent – exhibit persistent symptoms after treatment, which can include chronic fatigue, muscle and joint pain, headaches, episodes of “dizziness” or blackouts, cognitive difficulties and/or arthritis. After six months, given significant impairment in quality of life, these patients may be diagnosed with PTLDS (post-treatment Lyme disease syndrome).

We don’t know the cause of PTLDS, or why some patients develop this. Some hypotheses are that the Borrelia burgdorferi bacterium causes persistent infection somewhere in the body or that the symptoms are due to an aberrant immune response to Lyme infection, such as autoimmune disease.

**Comment**  This 5-15% is a number that has been pulled out of thin air.  Everyone I work with has chronic symptoms:  https://madisonarealymesupportgroup.com/2018/02/24/one-million-predicted-to-get-lyme-in-2018-in-the-u-s/   Davidsson writes in his conclusion:
“I am convinced that the history books in the future will describe controversy that exists today regarding chronic Lyme disease as one of the most shameful affairs in medicine.”

As for this persistence “hypothesis,” there’s over 700-peer reviewed studies showing borrelia persistence:  http://www.ilads.org/ilads_news/wp-content/uploads/2015/09/EvidenceofPersistence-V2.pdf

https://madisonarealymesupportgroup.com/2018/04/13/chronic-lyme-post-mortem-study-needed-to-end-the-lyme-wars/

What do you see as the next step in Lyme disease research?

Part of the reason why we haven’t been seeing clinical trials, vaccines, or drugs for Lyme disease is that we don’t have an accurate diagnostic test, and we would have no way of monitoring, for instance, effectiveness of a prospective vaccine or drug therapy in a clinical trial. We really need the diagnostic test to guide our potential treatments or prevention methods for the bacterium. I think it’s really going to be the development of better diagnostics that will drive potential therapies forward.

A second critical next step is identifying why is it that a proportion of patients with Lyme disease exhibit persistent symptoms that can last for months to years. We need to identify both the cause of PTLDS and identify potential treatments.

 

 

 

An Open Letter to the U.S. Media: What You Need to Know to Report Ethically in Science & Medicine

https://jameslyonsweiler.com/2018/05/28/an-open-letter-to-the-us-media-what-you-need-to-know-to-report-ethically-in-science-and-medicine/

May 28, 2018

By James Lyons Weiler

AS STEEPED IN THE PRIMARY BIOMEDICAL LITERATURE as my life is, I deeply appreciate the press when it covers advances, discoveries, controversies and new studies in science and medicine.

There are three types of such news articles, reflecting three types of reporters.
  • The first “articles”, Level C articles, are verbatim regurgitation of press releases from companies and universities. The quotes from researchers are faithfully reproduced, but there is no effort on the part of the reporter. They propagate proffered quotes included to help the public with interpretation or significance of the study. These articles, however, are not the result of critical analysis on the part of the news source, no attempt to place the report of the study into the context of current events, and no cross-reference to similar studies with similar or differing results. To me, these outlets are primarily a valuable source of information that studies exist. By definition, Level C articles contain information and carry forward the agenda of the organization issuing the press release.
  • The second type of article is an order of magnitude more valuable to readers, but actually does not require much additional work. In contrast to Level C articles, Level B articles do contain evidence of critical – and perhaps independent – analysis of the study. It will likely contain a list of limitations of the study. For example, it may mention if it had no control group, the fact that it is a survey study, or merely a retrospective study, which falls far short of a prospective randomized clinical trial. Level B articles likely include quotes obtained from direct interview of scientists. The best Level B articles will include quotes from scientists who are not involved in the study, and will include information on possible conflicts of interest reported by those who conducted the study. Level B articles will relate the findings to current events, and cross-reference the findings of the current study to other past studies to set the new findings in the context of the state of the science or current medical practice.
  • Level A Articles:  Truly investigative reporting on biomedical research the US is difficult to find. In part, Direct-to-Consumer Marketing compromises the integrity of news outlets. This is not a criticism, merely an observation. Just as politicians must accept donations from corporations or have no chance to win an election, news corporations must answer to their corporate sponsors.

No topic is more taboo among major US media outlets than vaccine risk. It took an announcement from from Robert DeNiro that the Tribeca film festival would screen the documentary “Vaxxed” for major news stations to discuss the claims of the film – which included direct evidence from a CDC scientist stating that results were excluded from studies linking vaccines to autism – and even then, the news coverage was nothing like it was in the 1980s.

The CBS investigative program 60 Minutes did not do an investigative inquiry – even though CBS had reported that the study in question “Disproves” the vaccine/autism link. The reporter, the Edward E. Murrow Award-winning journalist Sharyl Attkisson, to her credit, did re-interview the first author on the study, Dr. Frank DeStefano after news of William Thompson’s allegations surfaced. In that interview, DeStefano admitted a “possibility” that vaccines may cause autism in a genetically susceptible subgroup of individuals. Attkisson, who was no longer employed by CBS News, published the bombshell interview on her own website – but other news sources did not dare to broach the topic.

Some readers may recall that Tucker Carlson did host guest Robert F. Kennedy, Jr. on the topic on Fox News in prime time. This remarkable event occurred in a setting in which leadership at Fox News had changed. I asked why it took so long for Fox News to cover the issues – and Kennedy told me: “Roger Ailes told me he would fire any of his hosts who had me on to talk about vaccine safety”. There is no reason to doubt Kennedy: recall that Mish Michaels was fired by WGBH in Boston due to revealing her vaccine risk awareness prior to them hiring her.

I am a guest contributor for Kennedy’s organization, World Mercury Project, from time to time, but Kennedy’s org and I do not share any financial relationship. I celebrate Kennedy and Attkisson’s integrity and bravery in the face of hostility toward objective discussions and reporting on vaccine risk and injury.

We need more Sharyl Attkissons; we need more Level A articles, with original text that demonstrates a reporter’s capacity for independent thought, a lack of agenda, critical and contextual analyses, both for society and on the state of science and medical practice – regardless of the threats of loss of revenue to the news outlet.

Reporters who feel that they are not allowed to report objectively on vaccines or any other medical product for fear of loss of advertising revenue are individually complicit in each and every individual case of harm that might occur when patients unwittingly accept a medical procedure or a prescription from an unsafe product. The funds in their bank accounts from their paychecks amount to blood money for their silence, and their integrity is compromised. The first defense will, of course be rationalization – everyone does it, I’ll lose my job, I’ll never be hired by any other media news outlet. None of those realities absolve complicity.

I would encourage such individuals to slowly improve their reporting, a month at a time. Consider adding brief information on societal context first, then scientific/medical context, then independent interviews.

Reporting on vaccines after waking up to the thousands of studies that have followed the Wakefield study will be difficult. The realities are that the many studies cited by CDC and AAP

  1.  only studied one vaccine;
  2. were nearly all underpowered (not large enough to find a positive association if one existed);
  3. were filled with conflicts of interest;
  4. have been called out for fraud; and, most importantly,
  5. are not the only studies on the question, and that some studies have, in fact, found association. Clearly, nearly the entire media has swallowed the oft-repeated party lines on vaccine risk, and they thereby perpetuate myths that will lead to vaccine injury in some people.

If you are a reporter, imagine publishing a news article that a drug is safe for use, but in reality, 2% of individuals driving across will be seriously injured or die. Now 10%. Now 20%. At what point do you step out of the safety zone and risk your career? At what point do you show integrity? Now think about vaccines. If you feel a different amount of anxiety when considering reporting on vaccine risk, you are compromised.

To regain your integrity, which comes from within, shoot for Level A articles each and every time. Stand up to managers. When all this fails, contact Sharyl Attkisson and inquire how you can help build a media company. Check out her news program, Full Measure. I’m sure she would be happy to consider articles on topics in biomedicine and science. (contact: fullmeasurenews@gmail.com).