Archive for the ‘research’ Category

Lyme Research Project

https://www.lymedisease.org/ldo-launches-mylymedata/

Please consider taking part in the mylymedata project – a large-scale study of chronic Lyme Disease, as it’s been over 15 years since the NIH has funded a treatment trial for chronic Lyme.

The MyLymeData registry allows patients to pool their health information through a secure website. “Big data” projects use advanced technology to gather and analyze huge amounts of patient data, which can assist researchers in studying disease patterns and answering important questions such as Why do some people recover from Lyme disease, while others remain ill?

“Patients have more at stake in the diagnosis and treatment of Lyme disease than anyone else involved in their healthcare,” says Lorraine Johnson, JD, MBA, Chief Executive Officer of LymeDisease.org. “Analyzing large amounts of data can provide insight into how the disease progresses and how effective certain treatments are.”

Big data projects look at the actual care ordinary patients are prescribed by their treating physicians. “This is real-world research. We need to find out what treatments are the most effective in actual clinical practice and what factors affect treatment response,” says Dr. Raphael Stricker, a Lyme disease specialist in San Francisco.

In addition to analyzing disease patterns, MyLymeData hopes to attract researchers interested in launching clinical trials. Patient privacy is critical. To ensure data is protected and secure, LymeDisease.org has partnered with PatientCrossroads, the leading provider of patient registries for the National Institutes of Health.

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Category:

Activism, Lyme, research, Uncategorized

Nobel Prize awarded to Doctors Who Discovered Artemisinin and Ivermectin

http://articles.mercola.com/sites/articles/archive/2015/10/31/parasite-fighting-therapies.aspx?e_cid=20151031Z1_DNL_art_2&utm_source=dnl&utm_medium=email&utm_content=art2&utm_campaign=20151031Z1&et_cid=DM89176&et_rid=1195196480

Caythanhhaohoavang-nguyenlieuchinhdechietxuatArtemisinin

The 2015 Nobel Prize in Physiology or Medicine has been jointly awarded to Drs. Youyou Tu, William C. Campbell, and Satoshi Omura for their discoveries of Artemisinin and Avermectin, natural substances that treat parasitic diseases.

Campbell from Duke University and Omura of Kitasato University in Japan are sharing half of the $960,000 Nobel Prize award to develop Avermectin which has greatly reduced lymphatic filariasis which causes chronic swelling and “elephantiasis,” and river blindness – both caused by parasitic worms. The purified version was named Avermectin and was later developed into the anti-parasitic drug Ivermectin which is used in both animals and humans to treat a variety of parasites.

Youyou Tu, a pharmacologist turned to traditional Chinese herbal medicine when chloroquine’s effectiveness was waning with malaria on the rise. She had to go back to the ancient literature to successfully extract the active component from Artemisia annua. Artemisinin is able to rapidly kill malaria parasites at an early stage of development and is highly effective in both animals and humans. When used in combination therapy, Artemisinin is estimated to reduce malaria deaths by more than 20 percent overall and more than 30 percent in children which amounts to more than 100,000 lives saved each year in Africa alone.

Dr. Klinghardt addresses parasitic infections first in his MISIDS patients by giving them wormwood (Artemisinin), phospholipids, vitamin C, and various herbs.

Also, eating raw garlic that has been smashed first to activate the beneficial properties and raw pumpkin seeds may also help. Maintaining a health GI is paramount and using fermented foods and taking high-quality pro and prebiotics may help to prevent and eradicate parasitic infections.

Category:

Herbs, research, Uncategorized

Response to the Proposed Monoclonal Antibody Injection to Prevent Lyme Disease

https://www.change.org/p/the-us-senate-calling-for-a-congressional-investigation-of-the-cdc-idsa-and-aldf/u/13944776?tk=-q6Qjp9U5xBsfKfijcGzoHsOghM6B0xXtori7lxgItI&utm_source=petition_update&utm_medium=email

Carl Tuttle, a Lyme activist from New Hampshire, has written a letter to Dr. Klempner regarding the safety of the monoclonal antibody injection proposed to prevent Lyme Disease.

  1. There is no safety window to protect against infection. According to Dr. Burgdorfer who stated in 1999 that about 5-10% of ticks that are carrying Lyme have a systemic infection and have the disease already in their salivary glands and can transmit infection immediately.
  2.  There is no protection from blood transmission due to blood transfusion.
  3. It can not protect against transmission by feces, urine, or tick-excretes.
  4. It will not protect sexual transmission.
  5. It will not protect from congenital transmission. 28 Peer-Reviewed Studies http://home.comcast.net/~runagain/Congenital%20Transmission%20of%20Lyme.doc

Category:

Activism, Lyme, research, Uncategorized, vaccines

Another Unknown Illness Spread by Ticks

http://www.telegraph.co.uk/news/health/news/11953087/New-illness-spread-by-ticks-found-similar-to-Lyme-disease.html

A nymph stage blacklegged tick on a leaf Infected nymphs transmit most cases of Lyme disease...AKPYYC A nymph stage blacklegged tick on a leaf Infected nymphs transmit most cases of Lyme disease

A nymph stage blacklegged tick

Scientists have found an illness similar to Lyme which is resistant to many antibiotics. The unnamed disease is carried by the bacteria Borrelia miyamotoi which has been found to be present in 3 out of 954 ticks in southern England. While there are no reports of illness in the UK, there have been 18 diagnoses in the United States in 2013.

There is concern that this unnamed illness could be mistaken for the flu or viruses as it causes relapsing fevers. If people do not receive prompt treatment symptoms become far more serious and pervasive.

Borrelia miyamotoi was identified 20 years ago in Japan but was not known to cause disease until 2011 when Durland Fish, Emeritus Professor at Yale School of Public Health said, “We stumbled across it at our laboratory in our colony of ticks. We reported it, but we could not get any funding. I happened to be at a conference in Cyprus where there were posters about an infection in Russia. I met the guy who was dealing with it and we exchanged notes.” He is hopeful a new antibiotic will be found for the disease.

Doctors have successfully treated the Borrelia miyamotoi illness with stronger varieties of antibiotics.

Category:

Lyme, research, Uncategorized

New Research to Prevent Lyme Disease

http://www.nbcnews.com/health/health-news/lyme-disease-treatment-would-prevent-infection-researchers-say-n441946

Dr. Mark Klempner of the University of Masachusetts’ nonprofit vaccine development arm, MassBiologics, states that they are working on a monoclonal antibody that specifically targets Lyme-causing bacteria that purports the highest level of immunity.

Using genetically engineered mice with human immune system genes, they immunized the mice using Borrelia bacteria and then collected the antibodies the mice produced. They identified four to be potent against multiple strains of Borrelia, the Lyme disease causing bacteria.

When testing the antibodies produced, a single injection protected them from a large dose of Borrelia even after several infected ticks bit the mice.

And while U.S. Biologic is working on a vaccine for mice, produced in pellets resembling kibble, Klemner states emphatically that their monoclonal antibody is not a vaccine, instead it stimulates the immune system to ward off infection.

Monoclonal antibody drugs have been used for various diseases including cancer. It is similar in approach to gamma globulin shots that were used to try and prevent tuberculosis and hepatitis.

The company is hopeful to start testing in humans next year.

Category:

Lyme, research, Uncategorized, vaccines