Vinyard Gazette: Scientists Study Martha’s Vineyard to Get to Root of Chronic Lyme
Carl TuttleHudson, NH, United States
Jul 13, 2026
God forbid we find better antimicrobials for treating Lyme disease because that would give the public an excuse not to take the Lyme vaccine soon to be released!!!
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From: CARL TUTTLE <runagain@comcast.net>
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Cc: linden.hu@tufts.edu <linden.hu@tufts.edu>; cseguin@partners.org <cseguin@partners.org>; jayanta.bhattacharya@nih.hhs.gov <jayanta.bhattacharya@nih.hhs.gov>; Stephanie.Haridopolos@hhs.gov <stephanie.haridopolos@hhs.gov>; kalachakra108@aol.com <kalachakra108@aol.com>; kbliegnermd@optonline.net <kbliegnermd@optonline.net>
Sent: Tuesday, June 30, 2026 at 02:26:37 PM EDT
Subject: Vinyard Gazette: Scientists Study Martha’s Vineyard to Get to Root of Chronic Lyme
Vinyard Gazette
Scientists Study Martha’s Vineyard to Get to Root of Chronic Lyme
https://vineyardgazette.com/news/2026/06/28/scientists-study-marthas-vineyard-get-root-chronic-lyme
By Ethan Genter June 28, 2026
Excerpt:
“We don’t really have any idea,” said Dr. Linden Hu, an infectious disease specialist at Tufts who is helping lead the research. “We had the same hypotheses we had 30 years ago with no clear .
“People are recruited when they have the tell-tale rash – one of the earliest signs of Lyme disease.”
Vineyard Gazette
Edgartown, MA
Attn: Ethan Genter, News Editor
Dear Ethan,
Please see the following eleven articles published in the peer-reviewed literature on dapsone combination therapy for Lyme disease and the MSIDS model. Does Dr. Hu really not know about them, or dismisses Dr. Horowitz’ results because it’s not based on a randomized trial? It is interesting that Tufts received millions of dollars of research money from the NIH and Horowitz couldn’t get a 250k grant approved for a randomized, multicenter trial. More on that found here:
Dr. Jay Bhattacharya; Fund Dr. Richard Horowitz’ R34 NIH grant on Dapsone treatment for Lyme disease
https://www.change.org/p/the-us-senate-calling-for-a-congressional-investigation-of-the-cdc-idsa-and-aldf/u/34365550
As for Hu’s research, it is focusing on the acute or early stage of the disease while patients who are the sickest went years or decades before obtaining a diagnosis ignoring the late-stage Lyme epidemic seen all across this nation. What academic discipline would Hu encounter if he focused on better antimicrobials???
11 Dapsone Articles on The Effective Treatment of Chronic LD & Associated Co-infections Including Bartonella: As of April 2026
Horowitz, R. Improving biomarkers of inflammation including phosphorylated tau in a patient with chronic Lyme disease/post-treatment Lyme disease syndrome using dapsone combination therapy: A case study and literature review. Journal of Alzheimer’s Disease Reports. April 27, 2026. DOI: 10.1177/25424823261445434 https://journals.sagepub.com/…/10.1177/25424823261445434
Horowitz, R.I.; Fallon, J.; Freeman, P.R. Combining Double-Dose and High-Dose Pulsed Dapsone Combination Therapy for Chronic Lyme Disease/Post-Treatment Lyme Disease Syndrome and Co-Infections, Including Bartonella: A Report of 3 Cases and a Literature Review. Microorganisms 2024, 12, 909. https://doi.org/10.3390/microorganisms12050909
Horowitz, R.I.; Fallon, J.; Freeman, P.R. Comparison of the Efficacy of Longer versus Shorter Pulsed High Dose Dapsone Combination Therapy in the Treatment of Chronic Lyme Disease/Post Treatment Lyme Disease Syndrome with Bartonellosis and Associated Coinfections. Microorganisms 2023, 11, 2301. https://doi.org/10.3390/microorganisms11092301
Horowitz RI, Freeman PR. Efficacy of Short-Term High Dose Pulsed Dapsone Combination Therapy in the Treatment of Chronic Lyme Disease/Post-Treatment Lyme Disease Syndrome (PTLDS) and Associated Co-Infections: A Report of Three Cases and Literature Review. Antibiotics. 2022; 11(7):912. https://doi.org/10.3390/antibiotics11070912
https://www.mdpi.com/2079-6382/11/7/912/htm
Horowitz, R.I.; Freeman, P.R. Efficacy of Double-Dose Dapsone Combination Therapy in the Treatment of Chronic Lyme Disease/Post-Treatment Lyme Disease Syndrome (PTLDS) and Associated Co-infections: A Report of Three Cases and Retrospective Chart Review. Antibiotics 2020, 9, 725. https://doi.org/10.3390/antibiotics9110725
Horowitz, R.I., Murali, K., Gaur, G. et al. Effect of dapsone alone and in combination with intracellular antibiotics against the biofilm form of B. burgdorferi. BMC Res Notes 13, 455 (2020). https://doi.org/10.1186/s13104-020-05298-6
https://bmcresnotes.biomedcentral.com/…/s13104-020
Horowitz, R.I.; Freeman, P.R. Precision Medicine: retrospective chart review and data analysis of 200 patients on dapsone combination therapy for chronic Lyme disease/post-treatment Lyme disease syndrome: part 1. International Journal of General Medicine 2019:12 101–119
https://www.dovepress.com/precision-medicine
https://www.ncbi.nlm.nih.gov/pubmed/30863136
https://www.ncbi.nlm.nih.gov/pubmed/30863136
Horowitz, R.I.; Freeman, P.R. Precision Medicine: The Role of the MSIDS Model in Defining, Diagnosing, and Treating Chronic Lyme Disease/Post Treatment Lyme Disease Syndrome and Other Chronic Illness: Part 2. Healthcare 2018, 6, 129.
https://www.ncbi.nlm.nih.gov/pubmed/30400667
Horowitz RI, Freeman PR (2016) Are Mycobacterium Drugs Effective for Treatment Resistant Lyme Disease, Tick-Borne Co-Infections, and Autoimmune Disease?. JSM Arthritis 1(2): 1008.
Horowitz RI, Freeman PR (2016) The Use of Dapsone as a Novel “Persister” Drug in the Treatment of Chronic Lyme Disease/Post Treatment Lyme Disease Syndrome. J Clin Exp Dermatol Res 7: 345. doi:10.4172/2155-9554.1000345
Tardo AC, McDaniel CE and Embers ME (2023). Superior efficacy of combination antibiotic therapy versus monotherapy in a mouse model of Lyme disease. Front. Microbiol. 14:1293300. doi: 10.3389/fmicb.2023.1293300
https://www.frontiersin.org/…/fmicb.2023.1293300/full
Dapsone documentary 2024:
https://drtalks.com/…/discover-healing-18-dapsone…/
Dapsone documentary 2025:
https://drtalks.com/…/dapsone-documentary-9-stories-of
Dr. H Podcast with Dr Alain Mass and Dr Charlie Bizilj on The Success of Dapsone Combination Therapy in the Treatment of Chronic Lyme Disease. May 21, 2025
https://us06web.zoom.us/…/TSVaYe6azIti
Passcode: &0yqten0
Dr. Horowitz has a new book and website, which has the 2000+ scientific references in Ending Chronic Illness listed on the site for review.
https://cangetbetter.com/
Respectfully Submitted,
Carl Tuttle
Independent Researcher
Hudson, NH
Cc:
-Dr. Linden Hu, Professor of Immunology at Tufts Medical School
-Claire Seguin, DNP, President and Chief Operating Officer of Martha’s Vineyard Hospital
-Bill Eville, Editor Vinyard Gazette
-Stephanie E. Haridopolos, MD, DABFM Principal Deputy Assistant Secretary for Health
-Jay Bhattacharya, Director of the National Institutes of Health
-Dr. Richard Horowitz, MD Board certified internist in private practice in Hyde Park, New York
-Dr. Kenneth B. Liegner Board Certified Internist with additional training in Pathology and Critical Care Medicine, practicing in Pawling, New York.
Paralyzed by Lyme, they were helped with combo treatments (please read!!!)
https://www.change.org/p/the-us-senate-calling-for-a-congressional-investigation-of-the-cdc-idsa-and-aldf/u/31772769
Madison Area Lyme Support Group 