Background: 10-20% of individuals diagnosed with Lyme disease develop chronic symptoms after antibiotic treatment.
Methods: A convenience sample of adults with self- reported, persistent post-Lyme treatment symptoms seeking treatment at the Lifespan Lyme Disease Center in Rhode Island completed a demographic and medical survey, the Patient Reported Outcomes Measurement Information System (PROMIS)-29 v2.0, and other short-form PROMIS measures of cognitive function, sleep disturbance, and fatigue.
Results: Compared to average standardized scale scores (T=50; SD=10), participants had mild impairments in physical (T=41) and social (T=42) functioning, mild symptoms of depression (T=56), anxiety (T=60), and sleep disturbance (T=57), and moderate pain interference (T=62), and fatigue (T=65). Participants reported greater symptoms than some other clinical samples including those with cancer and chronic pain. Post-hoc analyses revealed that women reported higher levels of fatigue than men.
Conclusions: People with persistent post-Lyme treatment symptoms report debilitating symptoms and functional impairments which must be considered in clinical care.
Once again the false percentage of 10-20% is being continually regurgitated and only serves to downplay the seriousness of this issue, and research monies are doled out to issues affecting the most people. A microbiologist has exposed the false, misleading percentages here. The 10-20% that are recognized are patients diagnosed and treated early. There is a much larger group (30-40%) that remains unrecognized due to being diagnosed and treated late. Combine the two groups and you have a whopping 60% OR MORE who go on to suffer debilitating symptoms. I can’t overstate the importance of this common flaw.