Tick-borne encephalitis (TBE) is a virus transmitted by ticks, which affects the central nervous system and is typically found in Europe and Asia. TBE is best-known to cause meningitis, meningoencephalitis, and meningoencephalomyelitis. There is no treatment for TBE, but the disease is preventable through vaccinations.

In an effort to better understand the role of the immune responses in the clinical course and post-treatment outcome of tick-borne encephalitis, Bogovič  and colleagues “assessed 24 cytokines and chemokines associated with innate and adaptive (T and B cell) immune responses.”

The study entitled Inflammatory Immune Responses in Patients with Tick-Borne Encephalitis: Dynamics and Association with the Outcome of the Disease compared the levels of inflammatory mediators during acute illness and later at follow-up time points

“to evaluate whether immune responses at each time point were associated with the outcome of the disease.”¹

1 in 3 patients with chronic symptoms

The authors found that “at least 30% of patients develop a post-encephalitic syndrome (PES), and approximately 5% are affected by permanent pareses.”

These patients report having

persistent symptoms such as fatigue, arthralgias and myalgias, headache, dizziness, sleep disorders, emotional lability, memory and concentration disorders, etc., termed PES.”

Post-encephalitic syndrome may be due to “inappropriate activation of host immune responses following [tick-borne encephalitis virus] infection,” the authors suggest.

Furthermore, this “immune response may take months to years to return to homeostasis.”

A new study finds 1 in 3 patients with tick-borne encephalitis develops chronic symptoms. CLICK TO TWEET

“These findings provide new insights into the immunopathogenesis of TBE [tick-borne encephalitis] and implicate inflammatory immune responses with post-encephalitic syndrome years after the initial infection,” the authors conclude.

Tick-borne encephalitis and Lyme disease

  • A black-legged (Ixodes spp) tick can transmit infectious pathogens causing both TBE and Lyme disease.
  • Although there is no antiviral treatment for TBE, antibiotics can be used to treat Lyme disease and many of the co-infections.
  • There is currently a vaccine for tick-borne encephalitis. But the vaccine to prevent Lyme disease and co-infections was voluntarily taken off the market in 2002.

Individuals with tick-borne encephalitis can also be infected with Borrelia burgdorferi. In one study, “62 (9.1%) [patients] had proven co-infection with borreliae and 240 (35.1%) had possible co-infection,” writes Velušcek.² Meanwhile, proven borrelial co-infections have been reported even higher (13.5% and 16.7%) in other studies, writes. Velušcek.

  1. Bogovič P, Lusa L, Korva M, Lotrič-Furlan S, Resman-Rus K, Pavletič M, Avšič-Županc T, Strle K, Strle F. Inflammatory Immune Responses in Patients with Tick-Borne Encephalitis: Dynamics and Association with the Outcome of the Disease. Microorganisms. 2019 Oct 31;7(11).
  2. Velušček M, Blagus R, Cerar Kišek T, Ružić-Sabljić E, Avšič-Županc T, F Bajrović F, Stupica D. Antibiotic Use and Long-Term Outcome in Patients with Tick-Borne Encephalitis and Co-Infection with Borrelia Burgdorferi Sensu Lato in Central Europe. A Retrospective Cohort Study. J Clin Med. 2019 Oct 20;8(10).



I find it interesting that regarding tick-borne encephalitis virus, there is no pharmaceutical treatment, yet people are tripping all over themselves for a treatment for COVID-19 which also is supposedly a virus.  A virus is a virus is a virus.  Why is COVID-19 any different?  (Perhaps it’s a big money maker?)

Of course, Lyme literate doctors utilize many natural options for viruses with success in bolstering the immune system, unlike the highly sought after pharmaceutical options represented for COVID-19, which incidentally make huge profits:

Things like high dose vitamin C, zinc, monolaurin, vitamin D, fish oil, and ozone, have been utilized successfully not only for tick-borne viral infections but for COVID-19 as well:

This article points out the obvious ‘elephant in the room’ that those with metabolic disease struggle with COVID-19 more severely:  The obvious answer here is dietary and lifestyle choices.  This issue would be true for anyone struggling with chronic illness. Anything that drives inflammation should be dealt with first and fore-most, yet authorities would rather put a band-aid on it and reap massive profits by insisting on a prescription drug.