Chronic Lyme Disease: An Evidence-Based Definition by the ILADS Working Group

International Lyme and Associated Diseases Society.
Antibiotics 2019, 8(4), 269; (registering DOI)
Received: 8 October 2019 / Revised: 9 December 2019 / Accepted: 11 December 2019 / Published: 16 December 2019
(This article belongs to the Special Issue Antibiotics Resistance of Borrelia)
Objective: Chronic Lyme disease has been a poorly defined term and often dismissed as a fictitious entity. In this paper, the International Lyme and Associated Diseases Society (ILADS) provides its evidence-based definition of chronic Lyme disease. Definition: ILADS defines chronic Lyme disease (CLD) as a multisystem illness with a wide range of symptoms and/or signs that are either continuously or intermittently present for a minimum of six months. The illness is the result of an active and ongoing infection by any of several pathogenic members of the Borrelia burgdorferi sensu lato complex (Bbsl). The infection has variable latency periods and signs and symptoms may wax, wane and migrate. CLD has two subcategories, CLD, untreated (CLD-U) and CLD, previously treated (CLD-PT). The latter requires that CLD manifestations persist or recur following treatment and are present continuously or in a relapsing/remitting pattern for a duration of six months or more.
Methods: Systematic review of over 250 peer reviewed papers in the international literature to characterize the clinical spectrum of CLD-U and CLD-PT.
Conclusion: This evidence-based definition of chronic Lyme disease clarifies the term’s meaning and the literature review validates that chronic and ongoing Bbsl infections can result in chronic disease. Use of this CLD definition will promote a better understanding of the infection and facilitate future research of this infection.
Shor, S.; Green, C.; Szantyr, B.; Phillips, S.; Liegner, K.; Burrascano, J., Jr.; Bransfield, R.; Maloney, E.L. Chronic Lyme Disease: An Evidence-Based Definition by the ILADS Working Group. Antibiotics 2019, 8, 269.
Please give this to each and every doctor and nurse you know.  This is not conjecture.
Thousands of people are walking around with chronic Lyme disease and it’s not going away.

Peer-Reviewed Evidence of Persistence of Lyme:MSIDS copy  Over 700 peer-reviewed articles showing pathogen persistence.

It’s also congenital (spread from mother to baby):

Dr. Lida Mattman, an expert on the cell wall deficient form of borrelia believes Lyme can be transmitted in many ways – including sexually:


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