Frequency of Borrelia Burgdorferi Western Blot & LTT Positivity Among Multiple Sclerosis Patients From Turkey

Barbaros Çetin*

Dokuz Eylul University, Faculty of Science, Department of Biology, Izmir, Turkey.

Article Received on 29/01/2019 Article Revised on 19/02/2019 Article Accepted on 12/03/2019

*Corresponding Author: Dr. Barbaros Çetin


In Turkey, Borrelia burgdorferi infections are not well known among physicians and almost completely overlooked. On the other hand, a small number of seropositivity studies (%3.3-%73) show that Borrelia burgdorferi is common in Turkey. There is no diagnostic biological marker in multiple sclerosis (MS). Only several clinical criteria used for diagnosis. These criteria are also compatible with other diseases. Lyme disease is currently among them.

In the chronic phase of Lyme, demyelination can form and this can be confused with MS. In this study 126 patients, between ages 17 and 66, with a definite diagnosis of multiple sclerosis was evaluated, and were found to be found positive Borrelia burgdorferi western blot and LTT test results 108 (%85.72). Only 18 (%14.28) patients have negative test results.

The results show that LYME disease is very common in Turkey and LYME patients with neurological symptoms are misdiagnosed with multiple sclerosis.



Important excerpt from study:

Spirochetes in MS” (Buzzard, E.F.), published in the famous Lancet magazine in 1911, revealed the presence of Lyme spirochetes in the brains of MS patients. Over a period of more than a century, more than 50 international scientific papers proving the MS-Lyme relationship have been published in prestigious medical journals.[16-111]

Please look at the date for that…...1911, yet, how many doctors are considering Lyme/MSIDS in those patients thought to have MS?

I will answer that question – very, very few. 


Courtesy, Tom Grier 

For an informative article on the subject of cell-wall deficient forms (CWD) and other neurological diseases:

Dr. Lida Mattman, was a protégé of Gabriel Stiener who was the first to establish that MS was associated with a spirochete.

Grier states that this area of microbiology has long been neglected, and that we are now paying a price for that neglect. Mattman’s work suggests that cell wall deficient forms are prevalent, pathogenic, and may be behind sarcoidosis, Crohn’s disease, coronary thrombosis, Kaposi’s sarcoma, endocarditis, and MS.

Mattman explains her simple lab technique here:  Transcript included. 

According to Grier, Mattman said she frequently isolates L-forms from Lyme patients with aseptic meningitis and endocarditis, but that traditional culture media is virtually worthless, as are traditional heat fixed blood smears. Instead, she creates a live wet mount using the patients blood or bully coat. The blood sample is placed on a wet slide with acrodine orange dye to stain the nucleic acids. Then a monoclonal antibody fluorescent stain that is specific for Borrelia burgdorferi is added and is examined under a microscope. Grier states most labs are clueless about cell wall deficient forms and that we will not have answers until more labs agree to test for CWD forms.






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