https://www.ncbi.nlm.nih.gov/pubmed/30556097/

2019 Jun;119(2):207-214. doi: 10.1007/s13760-018-01067-2. Epub 2018 Dec 17.

Active neuroborreliosis or inflammation: are the diagnostic guidelines at stake?

Abstract

Neuroborreliosis can induce a variety of neurological syndromes: e.g., cranial neuritis, plexitis, radiculitis, meningitis, cerebellitis, … We report on five cases of patients with a diagnosis of neuroborreliosis based on clinical symptoms, serologic tests and MR imaging results. However, neither of them fulfils the diagnostic criteria for definite neuroborreliosis. Are the diagnostic criteria still valid or is there a need to revise them? Is our diagnosis correct? Are these cases post-Lyme auto-immune neuronal inflammation, and not due to still active spirochetal infection? Do we need to consider immunosuppressive therapy instead of third-generation cephalosporins?

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**Comment**

All I know is plenty of research has indicated persistent infection:  Peer-Reviewed Evidence of Persistence of Lyme:MSIDS copy

Also, not mentioned is the possible presence of other infections:  https://madisonarealymesupportgroup.com/2018/10/30/study-shows-lyme-msids-patients-infected-with-many-pathogens-and-explains-why-we-are-so-sick/

Of course, the problem is that testing for ALL the coinfections that often come with Lyme is abysmal….

Will someone please do this very needed work?  https://madisonarealymesupportgroup.com/2018/04/13/chronic-lyme-post-mortem-study-needed-to-end-the-lyme-wars/

Don’t you think this question of persistence has been asked for long enough?