History, Therapeutic Mechanisms & Safety of Chlorine Dioxide

February 14, 2025

https://pierrekorymedicalmusings.com/p/the-history-and-therapeutic-mechanisms?

The History and Therapeutic Mechanisms Of Chlorine Dioxide

Chlorine dioxide was discovered over 200 years ago. It’s use has steadily expanded into many industries and therapeutic applications despite a near global regulatory blockade on clinical research.

Pierre Kory, MD, MPA
Jan 26, 2025

I believe that my writings on chlorine dioxide are the most important (and the most dangerous) work I have yet done on Substack. Although several experts have written extensively on this topic previously (here, here, and here), this similar effort of mine simply results from my wish to become as knowledgeable as possible about this critically important therapeutic (there is no better way to do so than personally researching and writing about a topic).

This is the 3rd in my ongoing series of posts. In the first two I presented the political context in which chlorine dioxide has been attacked during Covid (“Trump’s Bleach Conference”) and in the 2nd post I detailed the success achieved by Bolivia’s national chlorine dioxide program against Covid.

In this post I will review its discovery, chemical properties, industrial applications, and therapeutic mechanisms. Upcoming posts will cover the history of the attacks faced by the pioneering researchers and practitioners, followed by a review of the safety studies of oral ingestion and a compilation of studies showing efficacy in a number of diseases. Be sure to subscribe so as not to miss out on these critical upcoming posts.

Ultimately, what me and my growing network of clinical and scientific experts of this therapeutic compound want to achieve, is for the FDA (and the copycat regulatory agencies worldwide) to lift its restrictions on performing clinical research trials of chlorine dioxide in human diseases. If anyone from MAHA is reading this right now (and I know some are), please add chlorine dioxide (and DMSO) to the list of therapies currently being suppressed by the FDA that need to be reversed (RFK Jr listed more than a dozen other such therapies in the below recent tweet).  

Overall, studies and treatment experiences reveal that treatment with chlorine dioxide:

  1. is broadly antimicrobial against nearly all infectious pathogens
  2. reduces inflammation
  3. prevents scarring
  4. aids in wound healing
  5. is non-toxic when orally ingested (in appropriate concentrations)
  6. reduces oral plaque
  7. treats oral atrophic candidiasis
  8. is a potent deodorizer
  9. has in-vitro anti-cancer cell effects, stimulates an in-vivo anti-cancer cell immune response and is also effective when injected intra-tumorally, or via a combination of oral, enema, and IV administration.

This combination of properties is not found in any other compound. The therapeutic uses for chlorine dioxide are endless. (See link for article as well as for the reasons it’s different than bleach)

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https://pierrekorymedicalmusings.com/p/the-safety-of-orally-ingested-chlorine?

The Safety Of Orally Ingested Chlorine Dioxide At Commonly Used Treatment Doses

Contrary to the edicts of regulatory agencies worldwide that chlorine dioxide is “bleach,” “bleach-like,” or a “poison,” numerous studies show the safety of oral ingestion at treatment doses.

Pierre Kory, MD, MPA
Jan 30, 2025

Disclaimer:

Due to the history of persecutions and attacks on researchers and practitioners of chlorine dioxide as a therapy, I have to emphasize that in these posts, my intent is not to recommend treatment via oral ingestion of chlorine dioxide because;

  • It is not FDA approved for oral ingestion to treat any disease
  • It is not approved as an orally ingested therapy by any other regulatory agency in the world.
  • It is not classified as a food supplement.

Further, no chlorine dioxide formulation product on the market either meets or has been evaluated in terms of quality and safety for oral ingestion and thus do not meet Good Manufacturing Practice (GMP standards. Also, even if the over the counter products are relatively safe, it is doubtful that people know how to correctly make or store the resulting solution. For instance, it must be mixed with distilled water and be kept out of sunlight in amber glass or plastic bottles (never metal!). Further, (when exposed to sunlight there is a chance that chlorine can be produced, something that can introduce the potential for harm).

Thus, it would be illegal and irresponsible for me to recommend treatment via oral ingestion with it, despite the fact that numerous over-the-counter products for mucosal or skin applications have been allowed on the market (oral, nasal, sinus, and skin).

What is weird is that although it would be illegal for me or anyone to treat Covid with it, a law was passed in Bolivia in early Covid (over the strenuous objections of the regulatory health agencies) which allowed for the widespread manufacture and distribution of chlorine dioxide to be taken by oral ingestion by the military and universities there (albeit under controlled and standardized processes). Millions of Bolivians thus were treated with oral ingested chlorine dioxide for Covid. This effort, I believe, is the reason Bolivia’s outcomes in Covid were the best in South America, something I covered in a prior post on chlorine dioxide here.

From ChemicalSafetyFacts.org: Nearly 500 years ago, Swiss physician and chemist Paracelsus expressed the basic principle of toxicology: “All things are poison and nothing is without poison; only the dose makes a thing not a poison.” This is often condensed to: “The dose makes the poison.” It means that a substance that contains toxic properties can cause harm only if it occurs in a high enough concentration.  (See link for article)

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**Comment**

Kory points out that ‘authorities’ don’t recommend oral CDS due to toxicity and danger, but they never clearly indicate either the dose or administration route for this supposed toxicity.  Since it is regularly used globally for water purification, humans routinely ingest CDS.

The EPA has registered CDS as a “pesticide” [i.e. antimicrobial] due to its ability to eliminate microorganisms such as bacteria, viruses, and parasites from surface water, thereby rendering it safe to drink(EPA, 2006)

Kory then goes through all the hoops to show the doses used in treatment protocols are far less than what has been established to produce adverse effects in chronic ingestion and nowhere near the levels used in industrial applications.  It’s also less lethal than caffeine.  He explains the differences between Mineral Miracle Solution (MMS) and Chlorine Dioxide Solution (CDS) as well as chlorine, chloride, chlorate and chlorite. Dr. Klacker mo longer recommends the two-component CD (also known as MMS) due to adverse effects like diarrhea or vomiting, more acidic pH level, and sodium chlorite which can cause secondary reactions in the stomach.  CDS (ClO2) us a gas dissolved in water which is neutral pH and does not contain chlorite salts.

There are dozens of papers extolling the benefits and safety of topical CDS for wound management and microbial control.  A guidebook also states a mouthwash with CDS managed chronic candidiasis.  Due to the organisms the make up our microbiome generating significant amounts of reactive oxygen species (ROS), we are protected from the oxidizing effects of CDS, but it is strong enough to kill pathogens.

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