Madison Area Lyme Support Group

By Peter A. McCullough, MD, MPH

The Spanish Influenza pandemic was over with in two years 1918-1919. There was an insignificant attempt at mass vaccination and largely the outbreak ran its course affecting one third of the world’s population.

With SARS-CoV-2 being engineered in the Wuhan Institute of Virology intentionally as a human biologic threat coupled with with a global, planned mass vaccination campaign by the Bio-Pharmaceutical Complex, the COVID-19 pandemic is extending into its fourth year.

The CDC Nowcast system indicates as of December 23, 2023, that 44% of the Omicron subvariants are JN.1

Yang et al recently published observations that JN.1 has a unique mutation in the receptor binding domain of the Spike protein making it an immune escape artist.

“In summary, JN.1, by inheriting BA.2.86’s antigenic diversity and acquisition of L455S, rapidly achieved extensive resistance across receptor binding domain class 1, 2, and 3 antibodies, and showed higher immune evasion compared with BA.2.86 and other resistant strains like HV.1 and JD.1·1, at the expense of reduced human ACE2 binding. This evolutionary pattern, similar to the previous transition from BA.2.75 to CH.1.1 and XBB, highlights the importance of closely monitoring strains with high human ACE2 binding affinity and distinct antigenicity, like BA.2.86 and BA.2.75, despite their unremarkable immune evasion capabilities. Such strains could survive and transmit at low levels since their antigenic difference would allow them to target distinct populations compared with dominant strains and have the potential to quickly accumulate highly immune-evasive mutations at the cost of human ACE2 binding capabilities.”

The JN.1 subvariant which is likely to breakthrough natural and vaccine immunity with ease, is all the more reason to be armed and ready…..  (See link for article)

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**Comment**

According to this, JN.1 patients are presenting two the two distinct symptoms of headache and diarrhea.  The other symptoms are very similar to previous Omicron variants and include fever, fatigue, sore throat, and even runny nose, congestion, muscle aches, and other GI issues like nausea and loss of appetite.

I recently had another bout of something.  What was unique this time was vocal box involvement giving me Laryngitis.  This eventually moved into my chest causing severe coughing.  This drug on and on until I finally requested antibiotics (clindamycin) which set me straight again.  I also used Dr. Levvy’s food grade hydrogen peroxide nebulizer treatment as well as ivermectin, vitamin C, and the usual immune helps.

I found this interesting:  https://www.theepochtimes.com/health/potential-covid-induced-vocal-cord-paralysis-in-adolescents  The case of a 15-year old presented within is severe and I did not have difficulty swallowing or shortness of breath but this patient also had a history of asthma and anxiety. Adults have also had vocal fold paralysis or weakness with COVID as well, and the paralysis can be temporary or permanent.

So it appears this vocal chord involvement is now being seen more.