Version 1. . 2019; 8: F1000 Faculty Rev-763.
Published online 2019 May 31. doi: 10.12688/f1000research.18379.1
PMCID: PMC6545822
PMID: 31214329

Recent discoveries and advancements in research on the Lyme disease spirochete Borrelia burgdorferi

Christa Winslow, Writing – Original Draft Preparation1 and Jenifer Coburn, Writing – Review & Editinga,1,2


This review highlights some of the highest-profile developments and advancements in the research on Borrelia burgdorferi, the Lyme disease spirochete, that have emerged in the last two years. Particular emphasis is placed on the controversy surrounding genus nomenclature, antigenic variation at the vlsE locus, genes involved in infectivity and virulence, membrane characteristics of B. burgdorferi, and developments in experimental approaches.



Research hailing from Milwaukee, WI.